DCC mediated attractive signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DCCDCC:NTN1NTN1NTN1:DCC oligomerNTN1:DCC oligomer:PTK2FAKATPNetrin-1:DCC oligomer:pFADK1ADPNetrin1:DCC oligomer:pPTK2:Fyn/srcMyrG-p-Y419-SRC,MyrG-p-Y420-FYNNetrin-1:pDCC dimer:pFAK:Src/FynNCK1Netrin-1:pDCC oligomer:pFAK:Fyn:NCK1DOCK1,TRIONetrin:DCC oligomer:pFAK:Fyn:Nck-1:Rho GEFs DOCK/TrioGTPActive Cdc42 bound to Netrin:DCC complexGDPCDC42:GDPRAC1:GDPActive Rac1 bound to Netrin-1-DCC complexNTN1:DCC:NCK1:CDC42:GTP:Active N-WASP:PIP2WASLPIP2Netrin-1:DCC:pFyn:Nck:Rac1-GTP:AblimABLIM
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025