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Type II Na+/Pi cotransporters

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-427589

PubChem

R-HSA-427589

Description

The SLC34 family of type II Na+/Pi cotransporters consist of three members; NaPi-IIa (SLC34A1), NaPi-IIb (SLC34A2) and NaPi-IIc (SLC34A3) (Murer H et al, 2004). They are expressed mainly in the kidney and small intestine, located at the apical sites of epithelial cells although other areas of the body express them to a lesser extent. NaPi-IIa and b cotransports divalent Pi (HPO4[2-]) with three Na+ ions (electrogenic transport) whereas NaPi-IIc cotransports divalent Pi with two Na+ ions (electroneutral transport).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 3** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O95436	Sodium-dependent phosphate transport protein 2B	SLC34A2	view
Q06495	Sodium-dependent phosphate transport protein 2A	NPT2 SLC17A2 SLC34A1	view
Q8N130	Sodium-dependent phosphate transport protein 2C	NPT2C NPTIIC SLC34A3	view

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