Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
G-alpha(q)11,14,15,Q:G-beta:G-gammaG-alpha(q) 11,14,15,Q:GTPG-beta:G-gammaPLC beta1,2,3PLC beta1,2,3:G-alpha(q):GTPPIP2DAGIP3H2OFFAR1 ligandsFFAR1:fatty acidFFAR1FFAR1:rosiglitazonerosiglizoleGTPGDPG-alpha(q)11,14,15,Q:GDP:G-beta:G-gamma
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025