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MIRAGE
Depolymerization of the Nuclear Lamina

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPADPp-S106-LPINLPINPiH2OPhosphatidic acidDAGCa2+DAG:active PKC:Ca+2p-PKCA, p-PKCBp-S395-Lamin dimersEMD/ TMPO/ LEMD3/ LEMD2EMD/TMPO/LEMD3/LEMD2:Lamin filamentsp-S22/23, S395-Lamin dimers
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P17252 Protein kinase C alpha type
  • PKCA
  • PRKACA
  • PRKCA
 view
P20700 Lamin-B1
  • LMN2
  • LMNB
  • LMNB1
 view
P50402 Emerin
  • EDMD
  • EMD
  • STA
 view
Q8NC56 LEM domain-containing protein 2
  • LEMD2
 view
Q9Y2U8 Inner nuclear membrane protein Man1
  • LEMD3
  • MAN1
 view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025