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MIRAGE
HuR (ELAVL1) binds and stabilizes mRNA

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HuRADPATPHuRHuRmRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.HuR with phosphoserine221 and phosphoserine158:mRNA ComplexHuR with phosphoserine221 and phosphoserine318:mRNA ComplexmRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318HuR with Unknown Phosphorylation: mRNA ComplexmRNA Transcript Targeted by HuR with Unknown PhosphorylationTNFSF13HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1SETCANXPO1ANP32AHuR:mRNA complexesTNFSF13HuR:mRNA Complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O14980 Exportin-1
  • CRM1
  • XPO1
 view
O75888 Tumor necrosis factor ligand superfamily member 13
  • APRIL
  • TALL2
  • TNFSF13
  • ZTNF2
 view
P17252 Protein kinase C alpha type
  • PKCA
  • PRKACA
  • PRKCA
 view
P35658 Nuclear pore complex protein Nup214
  • CAIN
  • CAN
  • KIAA0023
  • NUP214
 view
Q01105 Protein SET
  • SET
 view
Q15717 ELAV-like protein 1
  • ELAVL1
  • HUR
 view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025