RHO GTPases activate PKNs

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
H2OPip-T19,S20-MRLC-smooth muscle/non-muscle myosin IISmooth muscle/non-muscle myosin IIRHOA,RHOB,RHOC,RAC1:GTPRHOA,RHOB,RHOC,RAC1:GTP:PKN1-3PKN1-3PDK1:PIP3RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3ATPp-T774-PKN1,p-T816-PKN2,p-T718-PKN3ADPp-T774-PKN1p-T774-PKN1:CDC25CCDC25Cp-S216-CDC25CCPI17p-T38-CPI-17MLCP:p-T38-PPP1R14AMyosin phosphatase14-3-3 dimerp-S216-CDC25C:14-3-3 protein complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025