Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AR:Androgensp-T774-PKN1:AR:Androgenp-T774-PKN1p-T774-PKN1:AR:Androgenp-T774-PKN1:AR:Androgen:NCOA2NCOA2KLK2,3 Gene:Nucleosome with H3K9me3p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3ADPATPp-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4CKDM4CO2p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H32OGCO2CH2OSUCCAKDM1Ap-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1Ap-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1Ap-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3KLK2,3 genesKLK2,KLK3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 27 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O60341 Lysine-specific histone demethylase 1A
  • AOF2
  • KDM1
  • KDM1A
  • KIAA0601
  • LSD1
view
O60814 Histone H2B type 1-K
  • H2BC12
  • H2BFT
  • HIRIP1
  • HIST1H2BK
view
P04908 Histone H2A type 1-B/E
  • H2AC4
  • H2AC8
  • H2AFA
  • H2AFM
  • HIST1H2AB
  • HIST1H2AE
view
P06899 Histone H2B type 1-J
  • H2BC11
  • H2BFR
  • HIST1H2BJ
view
P07288 Prostate-specific antigen
  • APS
  • KLK3
view
P10275 Androgen receptor
  • AR
  • DHTR
  • NR3C4
view
P16104 Histone H2AX
  • H2AFX
  • H2AX
view
P20151 Kallikrein-2
  • KLK2
view
P23527 Histone H2B type 1-O
  • H2BC17
  • H2BFH
  • H2BFN
  • HIST1H2BO
view
P33778 Histone H2B type 1-B
  • H2BC3
  • H2BFF
  • HIST1H2BB
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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