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Regulation of necroptotic cell death

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-5675482

PubChem

R-HSA-5675482

Description

A regulated balance between cell survival and cell death is essential for normal development and homeostasis of multicellular organisms. Defects in control of this balance may contribute to autoimmune disease, neurodegeneration, ischemia/reperfusion injury, non alcoholic steatohepatitis (NASH) and cancer.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 14 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15294	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	OGT	view
P07900	Heat shock protein HSP 90-alpha	HSP90A HSP90AA1 HSPC1 HSPCA	view
P62979	Ubiquitin-ribosomal protein eS31 fusion protein	RPS27A UBA80 UBCEP1	view
P62987	Ubiquitin-ribosomal protein eL40 fusion protein	UBA52 UBCEP2	view
P98170	E3 ubiquitin-protein ligase XIAP	API3 BIRC4 IAP3 XIAP	view
Q13158	FAS-associated death domain protein	FADD GIG3 MORT1	view
Q13490	Baculoviral IAP repeat-containing protein 2	API1 BIRC2 MIHB RNF48	view
Q13546	Receptor-interacting serine/threonine-protein kinase 1	RIP RIP1 RIPK1	view
Q15628	Tumor necrosis factor receptor type 1-associated DEATH domain protein	TRADD	view
Q16543	Hsp90 co-chaperone Cdc37	CDC37 CDC37A	view

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