Dissolution of Fibrin Clot

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HRGhistidine-rich glycoprotein:plasminogenPLGPLATfibrin multimer, crosslinked:tissue plasminogen activator (one-chain)fibrin multimer, crosslinkedfibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogenPlasminfibrin digestion products (plasmin)fibrin multimer, crosslinked:tissue plasminogen activator (two-chain)fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogenfibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1PAI1fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1SERPINF2alpha-2-antiplasmin:plasminuPAPLAU(21-431):PI-PLAURuPARPLG(20-810):HRGHRGPI-PLAUR:PLAU(21-177):PLAU(179-431)PI-PLAUR:PLAU(21-177):PLAU(179-431):SERPINE1PAI-2PI-PLAUR:PLAU(21-177):PLAU(179-431):SERPINE1:SERPINB2PLG(20-810):aprotininBPTIanti-fibrinolyticsPLG(20-810):anti-fibrinolytics
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 11 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P00747 Plasminogen
  • PLG
view
P00749 Urokinase-type plasminogen activator
  • PLAU
view
P00750 Tissue-type plasminogen activator
  • PLAT
view
P04196 Histidine-rich glycoprotein
  • HRG
view
P05120 Plasminogen activator inhibitor 2
  • PAI2
  • PLANH2
  • SERPINB2
view
P05121 Plasminogen activator inhibitor 1
  • PAI1
  • PLANH1
  • SERPINE1
view
P07093 Glia-derived nexin
  • PI7
  • PN1
  • SERPINE2
view
P07355 Annexin A2
  • ANX2
  • ANX2L4
  • ANXA2
  • CAL1H
  • LPC2D
view
P08697 Alpha-2-antiplasmin
  • AAP
  • PLI
  • SERPINF2
view
P35237 Serpin B6
  • PI6
  • PTI
  • SERPINB6
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025