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MIRAGE
Interferon gamma signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
JAK1,2 inhibitorsIFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitorsIFNGR1:JAK1:INFGR2:JAK2SMAD7 geneSMAD7IFNG:IFNGR complexIFNG dimerIFNG dimer:IFNG inhibitorsIFNG inhibitorsATPIFNG:IFNGR1:JAK1:IFNGR2:p-JAK2ADPIFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2YBX1p-S32,S36-YBX1p-S32,S36-YBX1STAT1-1STAT1 bound to p-IFNGR1p-STAT1(Y701) bound to p-IFNGR1p-STAT1 dimer bound to p-IFNGR1p-STAT1:p-STAT1 dimerp-STAT1 homodimerIFNG-regulated genes with GAS promoter elementsGAF bound to GAS promoter elementCIITAPTAFRIRF 1-9GBPOAS proteinsB2M(21-119)SP100MT2AGILTMHC class II alpha/beta dimerClass I MHC heavy chain (MHC HC)FCGRAIFN-gamma upregulated CAMsPMLIFNG induced TRIMs
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 51 - 52 of 52 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha
  • CAMK2A
  • CAMKA
  • KIAA0968
 view
Q9Y6K5 2'-5'-oligoadenylate synthase 3
  • OAS3
 view
Displaying all 4 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_002323 P05362 Intercellular adhesion molecule 1 view
GL_002347 P13591 Neural cell adhesion molecule 1 view
GL_002758 P01911 HLA class II histocompatibility antigen, DRB1 beta chain view
GL_002832 P01903 HLA class II histocompatibility antigen, DR alpha chain view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025