RAC1 GTPase cycle

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GTPGDPRAC1:GTPRAC1:GDPH2OPiRAC1:GDP:RAC1 GDIsARHGDIA,ARHGDIBRAC1:GTP:RAC1 effectorsRAC1 effectorsRAC1:GTPRAC1:GTP:RAC1 endoplasmic reticulum effectorsRAC1 endoplasmic reticulum effectors
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 91 - 100 of 123 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q92558 Actin-binding protein WASF1
  • KIAA0269
  • SCAR1
  • WASF1
  • WAVE1
view
Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma
  • PIK3R3
view
Q92619 Rho GTPase-activating protein 45
  • ARHGAP45
  • HMHA1
  • KIAA0223
view
Q96BY6 Dedicator of cytokinesis protein 10
  • DOCK10
  • KIAA0694
  • ZIZ3
view
Q96F07 Cytoplasmic FMR1-interacting protein 2
  • CYFIP2
  • KIAA1168
  • PIR121
view
Q96HP0 Dedicator of cytokinesis protein 6
  • DOCK6
  • KIAA1395
view
Q96N67 Dedicator of cytokinesis protein 7
  • DOCK7
  • KIAA1771
view
Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
  • ARAP1
  • CENTD2
  • KIAA0782
view
Q96QB1 Rho GTPase-activating protein 7
  • ARHGAP7
  • DLC1
  • KIAA1723
  • STARD12
view
Q96RT1 Erbin
  • ERBB2IP
  • ERBIN
  • KIAA1225
  • LAP2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025