Activated NTRK3 signals through PI3K

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NTF3:p-5Y-NTRK3 homodimerNTF3:p-5Y-NTRK3 homodimer:PI3KPIK3CA:PIK3R1NTF3:p-5Y-NTKR3 homodimer:MyrG-SRCMyrG-SRCATPADPNTF3:p-5Y-NTRK3 homodimer:MyrG-p-Y419-SRCIRS1(NTF3:p-5Y-NTRK3 homodimer,NTF3:p-5Y-NTRK3 homodimer:MyrG-p-Y419-SRC):IRS1(NTF3:p-5Y-NTRK3 homodimer,NTF3:p-5Y-NTRK3 homodimer:MyrG-p-Y419-SRC)PIP2PIP3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P12931 Proto-oncogene tyrosine-protein kinase Src
  • SRC
  • SRC1
view
P20783 Neurotrophin-3
  • NTF3
view
P35568 Insulin receptor substrate 1
  • IRS1
view
Q16288 NT-3 growth factor receptor
  • NTRK3
  • TRKC
view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025