Response of EIF2AK4 (GCN2) to amino acid deficiency

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATF4 mRNAATF4DDIT3 mRNACHOPATF4:CEBPB,CEBPG,DDIT3:TRIB3 geneTRIB3 geneCEBPB,CEBPG,DDIT3TRIB3CEBPB,CEBPGATF4:CEBPB,CEBPG:ASNS geneASNS geneASNStRNAtRNA:EIF2AK4:GCN1:80S Ribosome:mRNAGCN2:GCN1:80S ribosome:mRNAATPADPtRNA:p-T899-EIF2AK4:GCN1:80S Ribosome:mRNAMPp-S52-EIF2S1:EIF2S2:EIF2S3DDIT3 geneATF4 dimer:p-T69,T71-ATF2 dimer:DDIT3 genep-T69,T71-ATF2ATF3 geneATF4:ATF3 geneATF3CEBPB geneATF4:CEBPB geneLAPIMPACTIMPACT:GCN1:80S ribosome:mRNAGCN1:80S ribosome:mRNA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025