FCGR3A-mediated IL10 synthesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
cAMPPKA tetramer:4xcAMPPKA tetramerPRKACA,PRKACB,PRKACGcAMP:PKA regulatory subunitPKA catalytic subunitsATPp-S133-CREB1CREBADPCa2+Ca2+CALM1CALM1:4xCa2+LPG1G2IgG:LPG1G2IgGIgG:Lma antigens:FCGR3A:CD3 dimersIgG:Lma antigens:FCGR3A:p-CD3 dimersATPADPIgG:Lma antigens:FCGR3A:p-CD3 dimers:SYKSYKIgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYKLma amastigote surfaceIgG:Lma amastigote surfaceIgG:Lma antigensFCGRIIIA:CD3G/CD3Z dimersPLC gamma1,2IgG:Leishmania surface:p-FCGR3As:p-6Y-SYK:PLCGIgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-3Y-PLCGPIP3p-PLCGPIP2DAGH2OIP3ITPR:I(1,4,5)P3 tetramerIP3 receptor homotetramerPPiIL10 genep-S133-CREB1:IL10 geneIL10
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025