Potential therapeutics for SARS

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FURINFURIN:FURIN inhibitorsFURIN inhibitorsACE2ACE2_HUMANN-glycanchlorpromazineAP2:chlorpromazineAP-2 ComplexBRD4BRD4:fedratinibTG101348BTK inhibitorsBTK:BTK inhibitorsAntigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2CRBNCRBN:IMiDsIMiDsCYSLTR1 antagonistsCYSLTR1:CYSLTR1 antagonistsCYSLTR1FKBP1AFKBP1A:sirolimusAY-22989FKBP1A:tacrolimusFK506FNTB inhibitorsFNTA:FNTB:FTase inhibitorsFNTA:FNTBIMPDH inhibitorsIMPDH tetramers:IMPDH inhibitorsIMPDH tetramersIL1R1 inhibitorsIL1R1:IL1R1 inhibitorsIL1R1IL6RIL6R:IL6R inhibitorsIL6R inhibitorstype 1 interferon analogsIFNAR2:JAK1:STAT2:type 1 interferon analogsIFNAR2:JAK1:STAT2IFNAR2:JAK1:STAT2:JAK1,2 inhibitorsJAK1,2 inhibitorsIFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitorsIFNGR1:JAK1:INFGR2:JAK2JAK3 inhibitorsJAK3:JAK3 inhibitorsJAK3NFE2L2 inducersNFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2KEAP1:NEDD8-CUL3:RBX1:NFE2L2HSP90:ATP:FKBP4:PTGES3:NR3C1HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonistsNR3C1 agonistsRBVNS5B:ribavirinNS5BPDCD1 inhibitorsPDCD1:PDCD1 inhibitorsPD-1AP24534RIPK1:ponatinibRIP1ROCK1,ROCK2ROCK1,ROCK2:ROCKiROCKiS1PR1 agonistsS1PR1:S1PR1 agonistsS1PR1SIGMAR1SIGMAR1:dextromethorphanDEXMU-23000SIGMAR1:fluvoxaminedsDNA:ZBP1:pS-172-TBK1TBK1:amlexanoxAA-673HCQC-ter TLR7 dimer:HCQC-ter TLR7 dimerC-ter TLR9 dimer:HCQC-ter-TLR9 dimercolchicineTUBB:colchicineTUBBIFNAR1:TYK2IFNAR1:TYK2:TYK2 inhibitorsTYK2 inhibitorsVEGFA inhibitorsVEGFA-165 dimer:VEGFA inhibitorsVEGFA-165 dimerHDAC2 inhibitorsHDAC1:2-containing complex:HDAC2 inhibitorsHDAC1:2-containing complexVLA-4ITGA4:ITGB1:natalizumabAN100226COMT inhibitorsCOMT:COMT inhibitorsCOMTATP1A:ATP1B:FXYDATP1A:ATP1B:FXYD:cardiac glycosidescardiac glycosides
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025