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MIRAGE
Impaired BRCA2 binding to SEM1 (DSS1)
Summary
- Organism
- Homo sapiens (human)
- Reactome
- R-HSA-9763198
- PubChem
- R-HSA-9763198
- Description
-
- This pathway describes BRCA2 cancer mutations that affect the ability of BRCA2 to bind to SEM1 (DSS1), a small protein of 70 amino acids that regulates BRCA2 stability and its nuclear localization (reviewed in Le et al. 2021).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
| UniProt ID | Protein Name | Gene Symbol | Pathway Viewer |
|---|---|---|---|
| P51587 | Breast cancer type 2 susceptibility protein |
|
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