TGF-beta receptor signaling activates SMADs

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-2S-SMAD2,3p-2S-SMAD2,3:SMAD4SMAD4LTBP1, LTBP3LTBP1,LTBP3:TGFB:LAPTGFB:LAPTGFB1:LAP1LTBP4:TGFB1:LAP1Ltbp4LTBP1:TGFB1:LAP1LTBP1:TGFB1:LAP1:LAP1-binding integrinsLAP1 binding-integrinsLAP3-binding integrinsTGF-beta-3:LAP3:LAP3-binding integrinsTGFB3:LAP3Fibrillin-1LTBPs:Fibrillin-1LTBPsPre-TGFB1 complexTGF-beta-1:LAP1Dimeric TGFB1Dimeric TGFB1:TGFBR2 homodimerTGFBR2TGFBR1:FKBP1ATGFB1:TGFBR2:TGFBR1Fkbp1aATPTGFB1:TGFBR2:p-TGFBR1ADPZfyve9TGFB1:p-TGFBR:ZFYVE9:SMAD2/3SMAD2,3TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3TGFB1:p-TGFBR:ZFYVE9TGFBR2:CBLCBLNEDD8-AcM-UBE2MUbe2mQ62312
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025