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MIRAGE
HSP90 chaperone cycle for SHRs

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HSP70:ATPHSP40:HSP70:ATP:nascent proteinHSP40:nascent proteinHSP40:HSP70:ADP:nascent proteinPiHSP90:HSP90HSP40sStip1HSP90:STIP1:HSP70:nascent proteinHSP90:ATP:STIP1:HSP70:nascent proteinATPFkbp5HSP90:ATP:FKBP5:STIP1:HSP70:nascent proteinFkbp4HSP90:ATP:FKBP4:STIP1:HSP70:nascent proteinPtges3HSP90:ATP:FKBP4:PTGES3:nascent protein:HSP90:ATP:FKBP5:PTGES3:nascent protein:HSP90:ATP:FKBP4:PTGES3:ARHSP90:ATP:FKBP4:PTGES3:AR:AndrogensAndrogensHSP90:ATP:FKBP4:PTGES3:AR:AR agonistsAR agonistsHSP90:ATP:FKBP4:PTGES3:AR:AR antagonistsAR antagonistsHSP90:ATP:FKBP4:PTGES3:PGRHSP90:ATP:FKBP4:PTGES3:PGR:P4P4PGR agonistsPGR:PGR agonistsPGR:PGR antagonistsPGR antagonistsHSP90:ATP:FKBP4:PTGES3:NR3C1HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligandsNR3C1 ligandsHSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonistsNR3C1 agonistsMR ligandsHSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligandsHSP90:ATP:FKBP4:PTGES3:NR3C2NR3C2:NR3C2 antagonistsNR3C2 antagonistsFlorinef®NR3C2:fludrocortisoneHSP90:ATP:PTGES3:FKBP52:NR3C2:NR3C2 ligandsHSP90:ATP:PTGES3:FKBP52:PGR:P4HSP90:ATP:PTGES3:FKBP52:AR:AndrogensHSP90:ATP:PTGES3:FKBP52:NR3C1:NR3C1 ligandsH2OHSP90:HSP90HSP90 complexesSHR:SHFkbp4PiPtges3ADP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 13 of 13 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q9JHU4 Cytoplasmic dynein 1 heavy chain 1
  • Dhc1
  • Dnch1
  • Dnchc1
  • Dyhc
  • Dync1h1
 view
Q9QYJ0 DnaJ homolog subfamily A member 2
  • Dnaja2
 view
Q9QZB7 Actin-related protein 10
  • Act11
  • Actr10
  • Actr11
  • Arp10
  • Arp11
 view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025