Disassembly of the destruction complex and recruitment of AXIN to the membrane

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FRAT1,2FRAT1,2:GSK3betaGSK3BGSK3B:AXIN1WNT:FZD:LRP5/6:DVL:AXIN:GSK3BWNT:FZD:LRP5/6:DVLWNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3BATPADPWNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complexAmer1Ctnnb1ApcPP2AQ8BK63
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025