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RHO GTPases Activate NADPH Oxidases

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Rac1-GTPNOX2 complex:RAC1:GTPNOX2 complexTPNHO2.-H+O2TPNNOX2 complexNOX2 complex:RAC2:GTPRAC2:GTPO2O2.-NOX1 ComplexNOX1 complex:RAC1:GTPNOX3 ComplexNOX3 complex:RAC1:GTPPIADPATPPI3PNCF1:NCF2:NCF4p-S-345-NCF1:NCF2:NCF4Pin1PIN1:p-S-345-NCF1:NCF2:NCF4PIN1:p-S-6S-NCF1:NCF2:NCF4S100A8:S100A9:AA:Ca2+NOX2 complex:S100A8:S100A9:Ca2+
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P68404 Protein kinase C beta type
  • Pkcb
  • Prkcb
  • Prkcb1
 view
Q02956 Protein kinase C zeta type
  • Pkcz
  • Prkcz
 view
Q61093 NADPH oxidase 2
  • Cgd
  • Cybb
 view
Q672J9 NADPH oxidase 3
  • Nox3
 view
Q8CIZ9 NADPH oxidase 1
  • Nox1
 view
Q8VD65 Phosphoinositide 3-kinase regulatory subunit 4
  • Pik3r4
  • Vps15
 view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025