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Nonhomologous End-Joining (NHEJ)

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-5693571

PubChem

R-MMU-5693571

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 20 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O70445	BRCA1-associated RING domain protein 1	Bard1	view
P10853	Histone H2B type 1-F/J/L	H2b-f H2b-j H2b-l H2b-n H2bc7; H2bc11; H2bc13; H2bc15 Hist1h2bf Hist1h2bj Hist1h2bl Hist1h2bn	view
P62806	Histone H4	H4-12 H4-53 H4c1; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4c11; H4c12; Hist1h4m; H4c14; H4c16 H4f16 Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist2h4 Hist2h4a Hist4h4	view
P70399	TP53-binding protein 1	Tp53bp1 Trp53bp1	view
Q3UI43	BRISC and BRCA1-A complex member 1	Babam1 Merit40 Nba1	view
Q4U2R1	E3 ubiquitin-protein ligase HERC2	Herc2 Jdf2 Kiaa0393 Rjs	view
Q5PSV9	Mediator of DNA damage checkpoint protein 1	Kiaa0170 Mdc1	view
Q5U5Q9	BRCA1-A complex subunit RAP80	Rap80 Rip110 Rxrip110 Uimc1	view
Q61216	Double-strand break repair protein MRE11	Mre11 Mre11a	view
Q64475	Histone H2B type 1-B	H2bc3 Hist1h2bb	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

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