GlyCosmos Portal

Submissions

RAC1 GTPase cycle

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-9013149

PubChem

R-MMU-9013149

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 84 in total

1

2

3

4

5

…

Next ›

Last »
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
A2CG49	Kalirin	Kalrn	view
A6X8Z5	Rho GTPase-activating protein 31	Arhgap31 Cdgap Kiaa1204	view
B2RQE8	Rho GTPase-activating protein 42	Arhgap42 Graf3	view
B2RWW0	T-cell activation Rho GTPase-activating protein	Tagap	view
E9Q7D5	Rho guanine nucleotide exchange factor 5	Arhgef5	view
F8VPU2	FERM, ARHGEF and pleckstrin domain-containing protein 1	Farp1	view
F8VQ29	IQ motif containing GTPase activating protein 3	Iqgap3	view
O08579	Emerin	Emd Sta	view
O88643	Serine/threonine-protein kinase PAK 1	Pak1 Paka	view
P09055	Integrin beta-1	Itgb1	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

About Release Notes Help Feedback