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MIRAGE
Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Chaperones calnexin/BiPmonoglucosylated MHC class I HC:Calnexin/BiPmonoglucosylated MHC class I HCB2mMHC HC:B2M:Erp57MHC class I HC:Calnexin/BiP:Erp57TapbpMHC:B2M peptide loading complexBAP31 oligomerTAPCALRATPoligopeptideH2OPioligopeptideADPoligopeptideL-amino acidAntigenic peptide:MHC:B2M peptide loading complexErp57Antigen peptide bound class I MHC:BAP31 oligomerPeptide bound class I MHCSAR1B:GTPSAR1B:GTP:SEC23:SEC24SEC23:SEC24Sec13COPII vesicle with MHC class ISec31aSar1p:GTP:Sec23p:Sec24p:Ag bound MHC class ICOPII vesicle with MHC class ISEC23AGDPSAR1B:GDPAntigen peptide bound class I MHCSEC24GTPAntigen peptide bound class I MHCAntigen peptide bound class I MHC
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 21 - 24 of 24 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q80ZX0 SEC24 homolog B, COPII coat complex component
  • Sec24b
 view
Q8HWB2 Histocompatibility 2, Q region locus 4
  • H2-Gs10
  • H2-Q1
  • H2-Q4
  • H2-gs10
 view
Q9EQH2 Endoplasmic reticulum aminopeptidase 1
  • Appils
  • Arts1
  • Erap1
 view
Q9R233 Tapasin
  • Tapa
  • Tapbp
 view
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000252 P35564 Calnexin view
GL_000271 P14211 Calreticulin view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025