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MIRAGE
Downstream signal transduction

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PDGF:Phospho-PDGF receptor dimerPDGF:Phospho-PDGF receptor dimer:PI3KPI3KATPPIP3PIP2ADPPDGF:Phospho-PDGF receptor dimer:PLC-gammaPLCG1PDGF:p-PDGFR dimer:p-PLCgammaP10686PDGF:Phospho-PDGF receptor dimer:MyrG-SRCQ9WUD9PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRCPDGF:Phospho-PDGF receptor dimer:SHP2PTPN11Phospho PDGF beta receptor: PDGF chain B homodimerPhospho-beta receptor homodimer:GAPRasa1PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1GRB2-1:SOS1p21 RAS:GDPp21 RAS:GTPGDPGTPPDGF:phospho-PDGF receptor dimer:STATSTAT family membersCRK, CRKLPDGF:Phospho-PDGF receptor dimer:CrkPDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3GF1M8L9Bcar1NCK1,NCK2PDGF:Phospho-PDGFR receptor dimer:NckGrb7PDGF:Phospho-PDGF receptor dimer:Grb7
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025