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MIRAGE
Interleukin-2 signaling

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Il2IL2:IL2RAIl2raJAK1IL2RB:JAK1Il2rbIL2:IL2RA:IL2RB:JAK1JAK3JAK3:JAK3 inhibitorsJAK3 inhibitorsIL2:IL2R trimer:JAK1:JAK3IL2:IL2R trimer:p-JAK1:JAK3ATPADPIL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3Shc1IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHCSTAT5IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHCIL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5p-STAT5IL2:IL2R trimer:p-JAK1:JAK3:SYKSYKIL2:IL2R trimer:p-JAK1:JAK3:p-SYKJAK3:PYK2PTK2BJAK3:p-PYK2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P17108 Interleukin-2
  • Il-2
  • Il2
 view
P26896 Interleukin-2 receptor subunit beta
  • Il2rb
 view
P26897 Interleukin-2 receptor subunit alpha
  • Il2ra
 view
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001667 P17108 Interleukin-2 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025