GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **401 - 425** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Detoxification of Reactive Oxygen Species	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Cytochrome c 2.1 Glutathione S-transferase P Glutathione peroxidase 3 Glutathione peroxidase Glutathione reductase, mitochondrial Peroxiredoxin prdx-2 Probable cytochrome c 2.2 Probable glutathione reductase 2 Probable peroxiredoxin prdx-3 Probable thioredoxin-2 Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn] 1, mitochondrial Thioredoxin domain-containing protein Thioredoxin reductase 1 Thioredoxin-1	A0A0K3AUJ9 P10299 P19974 P30635 P31161 P34697 Q09433 Q17424 Q17745 Q21824 Q23240 Q8MXT1 Q8MYL7 Q93204 Q93379 Q95003 Q9U2M7	ctl-3 cyc-2.1 cyc-2.2 gpx-3 gpx-5 gsr-1 gst-1 ndx-4 prdx-2 prdx-3 prdx-6 prx2 sdm-1 sod-1 sod-2 tag-56 trx-1 trx-2 trxr-1 trxr-2	Caenorhabditis elegans
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Cystinosin homolog Excitatory amino acid transporter Mitochondrial carrier protein PET8 Putative sodium-dependent excitatory amino acid transporter glt-3 Putative sodium-dependent excitatory amino acid transporter glt-4 Putative sodium-dependent excitatory amino acid transporter glt-6 Vesicular GABA transporter	O18210 P34579 Q09500 Q10901 Q18934 Q21353 Q21751 Q22682 Q9UAY8	ctns-1 glt-1 glt-3 glt-4 glt-5 glt-6 glt-7 slc-25A26 slc-25a26 unc-47	Caenorhabditis elegans
Transferrin endocytosis and recycling	CUP-5L Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q8T666 Q95X44 Q95YD5 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	cup-5 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
WNT ligand biogenesis and trafficking	Abnormal cell lineage protein 44 GOLD domain-containing protein PX domain-containing protein Protein Wnt-1 Protein Wnt-2 Protein Wnt Protein mom-2 Protein wntless homolog Vacuolar protein sorting-associated protein 26 Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35	G5EG05 O01258 P34888 P34889 Q10459 Q21053 Q21336 Q27886 Q7YWX7 Q86D99 Q9XW41	cwn-1 cwn-2 egl-20 let-553 lin-44 mig-14 mom-2 mom-3 pvl-2 snx-3 tmed-1 vps-26 vps-29 vps-35 wnt-1 wnt-2	Caenorhabditis elegans
Regulation of PTEN localization	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Polyubiquitin-A RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ED20 G5EE01 H2L0K3 P0CG71 P37165 P49632 Q19818 Q7JKC3	daf-18 math-33 nhl-2 nhl-3 tam-1 ubia ubib ubl-1 ubq-1 ubq-2 usp-7	Caenorhabditis elegans
Insulin receptor recycling	Insulin-like receptor Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q95X44 Q95YD5 Q968Y9 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	daf-2 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
Clearance of dopamine	Sodium-dependent dopamine transporter	Q03614	dat-1	Caenorhabditis elegans
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein Inositol 1,4,5-trisphosphate receptor itr-1 Probable voltage-gated potassium channel subunit kvs-4 Rap guanine nucleotide exchange factor 1 Ras-related protein Rap-1 cAMP-dependent protein kinase catalytic subunit	A0A4V0INI0 G5EC00 H2KZQ6 J3K003 P21137 P34578 Q18246 Q20381 Q9XXD1 Q9Y0A1 U4PLR3	dec-4 epac-1 exp-2 itr-1 kin-1 kvs-1 kvs-2 kvs-3 kvs-4 kvs-5 lfe-1 rap-1 shw-1	Caenorhabditis elegans
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Inositol 1,4,5-trisphosphate receptor itr-1 Stromal interaction molecule 1 Transient receptor ion channel domain-containing protein	G5EF60 Q8I6Y9 Q9Y0A1	dec-4 itr-1 lfe-1 stim-1 trp-2	Caenorhabditis elegans
Linoleic acid (LA) metabolism	ABC transporter domain-containing protein Delta(5) fatty acid desaturase fat-4 Delta(6)-fatty-acid desaturase fat-3 Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Long chain fatty acid elongase 1 Long chain fatty acid elongase 2 Long chain fatty acid elongase 5 Long chain fatty acid elongase 6 Putative fatty acid elongase 3 Putative fatty acid elongase 4	F3Y5R4 G5EEE5 G5EG11 O45730 P49191 Q03574 Q20300 Q20303 Q20904 Q23221 Q9NAC6 Q9XVQ9	des-5 elo-1 elo-2 elo-3 elo-4 elo-5 elo-6 elo-7 elo-8 elo-9 fat-3 fat-4 pmp-4	Caenorhabditis elegans
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit homolog 1 protein	G5EFX6 Q22629	dgn-1 slt-1	Caenorhabditis elegans
Serotonin receptors	Dopamine receptor 2 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein	E7EM37 G5EGH0 P91096 Q22895 Q7JP61 Q86ME6	dop-1 dop-2 dop-2L dop-6 octr-1 ser-4 ser-7	Caenorhabditis elegans
Dopamine receptors	Dopamine receptor 2 Dopamine receptor 3 G-protein coupled receptors family 1 profile domain-containing protein	E7EM37 G5EGH0 Q6RYS9	dop-2 dop-2L dop-3 ser-4	Caenorhabditis elegans
Histamine receptors	Dopamine receptor 2 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Muscarinic acetylcholine receptor gar-3	E7EM37 G5EGH0 O45601 Q9U7D5	dop-2 dop-2L gar-3 ser-4 tag-89	Caenorhabditis elegans
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase family member 2	Q18253	dpf-2	Caenorhabditis elegans
Activation of G protein gated Potassium channels	G protein gamma domain-containing protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1	A0A1C3NSK2 A0A1C3NSN6 G5ECB2 G5ECT6 H2L0Q3 P17343 P52192 P54406 Q20636	eat-11 gbb-1 gbb-2 gbp-2 gpb-1 gpb-2 gpc-1 gpc-2 irk-1 irk-2 irk-3 irk-4	Caenorhabditis elegans
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	G protein gamma domain-containing protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1	A0A1C3NSK2 A0A1C3NSN6 G5ECB2 G5ECT6 H2L0Q3 P17343 P52192 P54406 Q20636	eat-11 gbb-1 gbb-2 gbp-2 gpb-1 gpb-2 gpc-1 gpc-2 irk-1 irk-2 irk-3 irk-4	Caenorhabditis elegans
EPH-Ephrin signaling	Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin receptor 1 Ephrin-4	G5EEE7 O44516 O61460 Q19475 Q9U3M2	efn-2 efn-3 efn-4 mab-26 vab-1 vab-2	Caenorhabditis elegans
Negative regulation of FGFR1 signaling	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Protein let-756 WAP-type 'four-disulfide core	G5EDX1 G5EEF1 P39745 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 kal-1 klo-1 klo-2 let-756 mpk-1 sur-1	Caenorhabditis elegans
FGFR1c ligand binding and activation	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756 WAP-type 'four-disulfide core	G5EDX1 G5EEF1 Q10656 Q11184	egl-15 egl-17 kal-1 let-756	Caenorhabditis elegans
FRS-mediated FGFR1 signaling	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EEF1 P22981 P29355 Q10656 Q11184 Q18758 Q9N5D3 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-341 let-60 let-756 lin-34 sem-5 sos-1	Caenorhabditis elegans
SHC-mediated cascade:FGFR1	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EEF1 P22981 P29355 Q10656 Q11184 Q18758 Q9N5D3 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-341 let-60 let-756 lin-34 sem-5 sos-1	Caenorhabditis elegans
SHC-mediated cascade:FGFR4	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EEF1 P22981 P29355 Q10656 Q11184 Q18758 Q9N5D3 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-341 let-60 let-756 lin-34 sem-5 sos-1	Caenorhabditis elegans
FRS-mediated FGFR4 signaling	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog	G5EEF1 P22981 P29355 Q10656 Q11184 Q18758 Q9N5D3 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-341 let-60 let-756 lin-34 sem-5 sos-1	Caenorhabditis elegans
Negative regulation of FGFR4 signaling	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 P39745 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-756 mpk-1 sur-1	Caenorhabditis elegans

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