GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **252** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Neurotransmitter receptors and postsynaptic signal transmission	Glycine receptor betaZ subunit (Fragment) Glycine receptor subunit alpha-2 Glycine receptor subunit alphaZ1	F1R8P4 O93430 Q9DES8	[b]Z fj42f03 glra1 glra2 glrb glrb1 glrba glyR beta wu:fj42f03	Danio rerio (zebrafish)
GP1b-IX-V activation signalling	Glycoprotein Ib platelet subunit beta LOC100004428 protein Nyctalopin Phosphatidylinositol 3-kinase regulatory subunit alpha Proto-oncogene tyrosine-protein kinase Src Tsukushi Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like isoform X1 von Willebrand factor	A4QNV9 B0S6V7 B8JLP1 E7F9Z1 Q00P20 Q1JPZ3 Q58A48 Q6P102	LOC100004428 VWF gp1bb hm:zehn0976 lrcc54 nyx pik3r1 si:ch1073-474e24.1 si:dkey-285c2.8 src tsk tsku vasn vasnb vwf wu:fb33b01 wu:fb65b05 ywhabl zgc:73065 zgc:77351	Danio rerio (zebrafish)
Platelet Adhesion to exposed collagen	Glycoprotein Ib platelet subunit beta LOC100004428 protein Nyctalopin Tsukushi von Willebrand factor	A4QNV9 B8JLP1 E7F9Z1 Q00P20 Q58A48	LOC100004428 VWF gp1bb lrcc54 nyx si:ch1073-474e24.1 si:dkey-285c2.8 tsk tsku vasn vasnb vwf	Danio rerio (zebrafish)
HS-GAG degradation	Glypican 2 Glypican 5a Glypican 6a Glypican-1 Glypican-3 Glypican-4 precursor Heparanase Iduronate 2-sulfatase precursor Syndecan 4 Syndecan	A1A5V0 A7MBT1 B3DJ94 F1QCC6 Q0JY12 Q1LVP9 Q66I66 Q6V9Y8 V5NES1 V5NF87	Gpc2 Gpc5a Gpc6a SDC4 cb440 chunp6920 fc47a08 fe05f10 gal3st4 gpc1 gpc2 gpc3 gpc4 gpc4/6 gpc5 gpc5a gpc6 gpc6a gpc6l hpse ids im:6970974 im:7144134 kny knypek sdc2 sdc4 sdc4l si:ch1073-86a3.1 wu:fc47a08 wu:fc47g09 wu:fe05f10 zgc:103676 zgc:158245 zgc:194854	Danio rerio (zebrafish)
Release of Hh-Np from the secreting cell	Glypican 5a Hedgehog protein Palmitoleoyl-protein carboxylesterase notum1a Protein dispatched homolog 2 Signal peptide, CUB and EGF-like domain-containing protein 2 Sonic hedgehog protein Tiggy-winkle hedgehog protein	A3KNS3 C5H5C4 Q5G872 Q6R5J1 Q90419 Q92008 V5NES1	Gpc5a disp2 gpc5 gpc5a hha ihh ihha notum1a scube2 shh shha shhb twhh vhh1 you	Danio rerio (zebrafish)
Activation of the phototransduction cascade	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit gamma Rhodopsin	P35359 Q6PBN9 Q803H5 Q90WX6	GNB1x fb39f01 fk56e06 gnat1 gnb1b gnb1l gng1 gngt1 rho wu:fb39f01 wu:fb98e06 wu:fj09d12 wu:fk53d06 wu:fk56e06 zfo2 zgc:55774 zgc:73318	Danio rerio (zebrafish)
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1a Plexin A3 Plexin-A1 Plexin-A2 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3ab Tyrosine-protein kinase fynb non-specific serine/threonine protein kinase	A0A2R8QPJ6 A8IYK2 B0S5N4 F1RDG9 O57521 Q0PWB7 Q5RG12 Q6BEA0 Q6DG42 Q7ZSZ9 Q8QFX6 Q9W686	cb422 cb820 fynb hsp90a.2 hsp90a2 hsp90aa1.2 hsp90ab1 hsp90b hspc3 kinase limk1 limk1a np-1 nrp1 nrp1a pak2 pak2a plxna1 plxna1b plxna2 plxna3 plxna4 rac1 rac1a sema3ab semaz1b si:dz198m22.1 wu:fb71h01 wu:fd16e02 zgc:55823 zgc:55917 zgc:86934 zgc:91798	Danio rerio (zebrafish)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin b1b RAS-related Ras-like protein Rnd1a Rho GTPase-activating protein 35 Rho-related GTP-binding protein RhoA-C	E7F8G5 F1Q7U0 F1QLR7 Q4V9D8 Q52WX7 Q7T2E8	LOC100004299 arhgap35a c-met cmet fb23a02 met plxnb1b rhoac rnd1a rnd1b rnd1l rras wu:fb23a02 wu:fj98h09 wu:fk50c04 zgc:153089 zgc:92588	Danio rerio (zebrafish)
HDACs deacetylate histones	Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone H3.2 Histone H4 Histone deacetylase 8 Polyamine deacetylase HDAC10 Uncharacterized protein LOC100126107	A3KPR4 A7E2M8 A7MCA8 B3DJF8 F1QCV2 Q4QRF4 Q5BJA5 Q5XJK2 Q6PC60 Q7SXM0 Q7ZTT0 R4GE15	LOC100150038 LOC100329358 LOC100331412 LOC100332229 LOC103908680 LOC108181627 LOC562770 LOC570661 LOC794549 h2af1al h2afx1 h2ax1 hdac10 hdac8 hist2h2l si:ch211-113a14.17 si:ch211-113a14.29 si:ch211-113a14.6 si:ch73-36p18.4 si:dkey-108k21.12 si:dkey-108k21.18 si:dkey-108k21.28 si:dkey-23a13.7 zgc:112234 zgc:113984 zgc:173585 zgc:173587 zgc:194998 zgc:56685	Danio rerio (zebrafish)
RNA Polymerase I Promoter Opening	Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Mbd2 protein Methyl-CpG binding domain protein 1 Methyl-CpG-binding domain protein 3 Mitogen-activated protein kinase Nucleolar transcription factor 1 Uncharacterized protein LOC100126107	A3KPR4 A7E2M8 A7MCA8 B3DJF8 F1QZ83 Q0Z946 Q4QRF4 Q5BJA5 Q5XJK2 Q6PC60 Q6PI20 Q6TGX7 Q71PD7 Q7SZX5 Q7ZTT0 Q7ZTV3 Q7ZVK8 R4GE15	ERK1 LOC100150038 LOC100329358 LOC100331412 LOC100332229 LOC103908680 LOC108181627 LOC562770 LOC570661 LOC794549 MBD3 fi06b09 h2af1al h2afvb h2afvl h2afx1 h2afza h2av h2ax1 h2az2a h2az2b h3-5 h3f3a h3f3b.1 h3f3c h3f3d hist2h2l im:6896397 mapk3 mbd1 mbd1b mbd2 mbd3a si:ch211-113a14.17 si:ch211-113a14.29 si:ch211-113a14.6 si:ch73-36p18.4 si:dkey-108k21.12 si:dkey-108k21.18 si:dkey-108k21.28 si:dkey-23a13.7 si:dz180g5.3 ubtf wu:fa97f06 wu:fa98f07 wu:fi06b09 wu:fi45g12 wu:fj38c10 zERK1 zK13A21.11 zK13A21.17 zgc:111862 zgc:112234 zgc:113984 zgc:173585 zgc:173587 zgc:194998 zgc:56685	Danio rerio (zebrafish)
NoRC negatively regulates rRNA expression	Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Mbd2 protein Methyl-CpG binding domain protein 1 Methyl-CpG-binding domain protein 3 Uncharacterized protein LOC100126107	A3KPR4 A7E2M8 A7MCA8 B3DJF8 Q0Z946 Q4QRF4 Q5BJA5 Q5XJK2 Q6PC60 Q6PI20 Q6TGX7 Q71PD7 Q7SZX5 Q7ZTT0 Q7ZTV3 R4GE15	LOC100150038 LOC100329358 LOC100331412 LOC100332229 LOC103908680 LOC108181627 LOC562770 LOC570661 LOC794549 MBD3 h2af1al h2afvb h2afvl h2afx1 h2afza h2av h2ax1 h2az2a h2az2b h3-5 h3f3a h3f3b.1 h3f3c h3f3d hist2h2l im:6896397 mbd1 mbd1b mbd2 mbd3a si:ch211-113a14.17 si:ch211-113a14.29 si:ch211-113a14.6 si:ch73-36p18.4 si:dkey-108k21.12 si:dkey-108k21.18 si:dkey-108k21.28 si:dkey-23a13.7 wu:fa97f06 wu:fa98f07 wu:fi45g12 zK13A21.11 zK13A21.17 zgc:111862 zgc:112234 zgc:113984 zgc:173585 zgc:173587 zgc:194998 zgc:56685	Danio rerio (zebrafish)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Paired amphipathic helix protein Sin3a Paired amphipathic helix protein Sin3b Protein arginine N-methyltransferase 6 Runt-related transcription factor Uncharacterized protein LOC100126107	A3KPR4 A5D6S0 A7E2M8 A7MCA8 B3DJF8 Q0Z946 Q1LYM8 Q4QRF4 Q5BJA5 Q5XJK2 Q6NWG4 Q6PC60 Q6PI20 Q71PD7 Q7ZTT0 Q9DGB8 R4GE15	LOC100150038 LOC100329358 LOC100331412 LOC100332229 LOC103908680 LOC108181627 LOC562770 LOC570661 LOC794549 fj63d08 h2af1al h2afvb h2afvl h2afx1 h2afza h2av h2ax1 h2az2a h2az2b h3-5 h3f3a h3f3b.1 h3f3c h3f3d hist2h2l im:6896397 prmt6 runx1 runxa si:ch211-113a14.17 si:ch211-113a14.29 si:ch211-113a14.6 si:ch73-36p18.4 si:dkey-108k21.12 si:dkey-108k21.18 si:dkey-108k21.28 si:dkey-23a13.7 si:dkey-6n6.6 sin3aa sin3b wu:fj63d08 zgc:112234 zgc:113984 zgc:173585 zgc:173587 zgc:194998 zgc:56685	Danio rerio (zebrafish)
Hyaluronan uptake and degradation	Hyaluronidase	Q29RC1	hyal1	Danio rerio (zebrafish)	G35674CY
Signaling by Activin	Inhibin beta A chain Inhibin beta B chain Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor	A1L1T8 B0S7E0 Q8AY15 Q9I9P9 Q9YGU4	ActrIIB actbb actbetaB actr2b actrIIb acvr2b acvr2ba inhbab inhbal inhbb madh2 madh3 madh3a smad2 smad3 smad3a wu:fa99e03 wu:fj97d11 zgc:158348	Danio rerio (zebrafish)
Antimicrobial peptides	Intelectin 1 precursor Intelectin 2 Intelectin 3 Liver-expressed antimicrobial peptide 2 NK lysin-like protein Peptidoglycan recognition protein 1 Peptidoglycan recognition protein 2 RNase 2 RNase 3 Ribonuclease-like 3 Uncharacterized protein LOC767641 isoform X1 lysozyme	A5HAK0 A5HAK1 A5HAK2 B3DGL6 C1IHU9 C1IHV0 F1QYP1 Q08CC6 Q1W1Y2 Q1W1Y3 Q7T3Q1 Q90YS5	INTL1 INTL2 INTL3 LOC793075 PGRP-SC1a im:7150573 intl2 intl3 itln1 itln2 itln3 leap2 lys-C lyz nkl.4 nkld pglyrp2 pglyrp5 pgrp-l rnasel2 rnasel3 rnasel4 si:ch211-139g14.6 si:ch211-194p6.4 si:ch211-202c21.3 si:dkey-113g17.4 si:rp71-40n14.1 wu:fj22b05 zgc:136734 zgc:153267 zgc:194626 zgc:194647	Danio rerio (zebrafish)	G49108TO
Interleukin-38 signaling	Interleukin-1 beta Interleukin-1 receptor accessory protein-like 1-B Mitogen-activated protein kinase 8	B6ZK77 K9K4N1 Q9DGD9	il-1FMA il1fma il1rapl1b jnk1 mapk8 zmp:0000001271	Danio rerio (zebrafish)
Axonal growth inhibition (RHOA activation)	Leucine rich repeat and Ig domain containing 4b isoform X1 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B Myelin-associated glycoprotein Nerve growth factor receptor b Reticulon Reticulon Rho GDP-dissociation inhibitor 1 Rho-related GTP-binding protein RhoA-C	A3KH16 E2DGP8 F1QSA4 Q4G5V0 Q4G5V7 Q66HV9 Q7T2E8 Q802W6	arhgdia fb64c01 im:7136397 lingo1 lingo1b lingo4b mag ngfrb ngfrl rhoac rtn1 rtn1a rtn4b rtn5 rtn6 siglec-4 wu:fa96g11 wu:fb64c01 wu:fc07e07 wu:fq24d12 zgc:113566 zgc:198379 zgc:55554 zgc:73298 zgc:77681 zgc:86778	Danio rerio (zebrafish)
Receptor-type tyrosine-protein phosphatases	Liprin-alpha-1 Receptor-type tyrosine-protein phosphatase F	A4IFW2 A9JR75	ppfia1 ptprf	Danio rerio (zebrafish)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Lysine-specific demethylase 5B-B Transcription factor AP-2 gamma Transcriptional regulator Myc-B	Q5PQZ4 Q6IQX0 Q7ZVS9	fb48g05 fb49c04 jarid1b jarid1bb kdm5bb mycb tfap2c wu:fb48g05 wu:fb49c04 zgc:92088	Danio rerio (zebrafish)
Lysosphingolipid and LPA receptors	Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 isoform X1 Lysophosphatidic acid receptor 5a Sphingosine 1-phosphate receptor 1 Sphingosine 1-phosphate receptor 2 Sphingosine 1-phosphate receptor 5	A0PJS0 F1QFF1 K9M3I1 Q6DHQ8 Q6PHE1 Q9DDK4 Q9I8K8	Lpar3 edg1 edg2 edg5 lpar1 lpar2a lpar3 lpar5a lpar6 lpar6l p2ry5 s1pr1 s1pr2 s1pr5b si:dz22b13.1 si:dz46m7.1 wu:fb62d01 zgc:101053 zgc:158362 zgc:66034 zgc:92157	Danio rerio (zebrafish)
Arachidonate production from DAG	Lysophosphatidylserine lipase ABHD12 Monoglyceride lipase sn-1-specific diacylglycerol lipase	E7F0B3 Q08C93 Q7ZWC2	MGLL abhd12 cb909 dagla mgll wu:fc66g01 zgc:56561	Danio rerio (zebrafish)
Zinc influx into cells by the SLC39 gene family	Metal cation symporter ZIP14 Zinc transporter ZIP1 Zinc transporter ZIP6	A0A0G2KQY6 P59889 Q6L8F3	liv1 slc39a1 slc39a14 slc39a6 zip1 zip14 zip6	Danio rerio (zebrafish)
LDL remodeling	Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	A0A0R4IPV5 A0A0R4IVV0	mtp mttp p4hb psmb3 zgc:92596	Danio rerio (zebrafish)
Organic anion transporters	Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial dicarboxylate carrier Mitochondrial glutamate carrier 1 Sialin Slc5a5 protein Sodium-coupled monocarboxylate transporter 1 Solute carrier family 25 (Mitochondrial carrier Solute carrier family 25 member 55b Tricarboxylate transport protein B, mitochondrial Vesicular glutamate transporter 1 Vesicular glutamate transporter 2.1 Vesicular glutamate transporter 3	A3QK31 A4IG60 E7F2B8 F1R4U0 Q08CH2 Q1L8X9 Q3ZMH1 Q5W8I8 Q6DHS4 Q6IQ89 Q7ZTT6 Q7ZWA7	MGC163045 blu cb229 fa07h09 sb:cb229 sb:cb809 si:ch211-200a16.4 slc17a5 slc17a6 slc17a6b slc17a7 slc17a7a slc17a8 slc25a10 slc25a10b slc25a11 slc25a18 slc25a1b slc25a22 slc25a55a slc25a55b slc5a5 slc5a8 slc5a8l smcte vglut1 vglut2.1 vglut2a vglut3 wu:fa07h09 wu:fa12h05 wu:fb72h03 zgc:153077 zgc:56592 zgc:56614 zgc:86898	Danio rerio (zebrafish)
TRP channels	Mucolipin 1.2 (Fragment) Mucolipin-2 Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4-associated protein Short transient receptor potential channel 6 isoform X1 TRPA1 TRPA2 Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily V member 1 Transient receptor potential cation channel subfamily V member 6 isoform X1 Transient receptor potential cation channel, subfamily C, member 4b Transient receptor potential cation channel, subfamily M, member 4a non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0R4IM91 A0A0R4IMY7 B6RTA2 E1U7G1 E7FBN6 F1QN56 F1RCY2 G4WAZ8 Q563W7 Q5UM14 Q5UM15 Q803Y8 Q9IAV5 S5TRY1 U3N9R0	ANKTM1 TRPM4a TRPV1 bZ1P14.9 cb495 ecac mcoln1.2 mcoln1b mcoln2 si:dkey-9e15.2 si:rp71-1p14.9 tap1A tap1a tct trpa1 trpa1a trpa1b trpa1l trpa2 trpc1 trpc4a trpc4apa trpc4b trpc6 trpc6a trpc7b trpm2 trpm4 trpm4a trpm6 trpm7 trpv1 trpv5-6 trpv6 wu:fb15d09 zgc:109818 zgc:55310	Danio rerio (zebrafish)

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