GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **128** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
ROS and RNS production in phagocytes	Metal transporter nramp1 homolog NADPH--cytochrome P450 reductase V-ATPase proteolipid subunit C-like domain-containing protein V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit d Vacuolar proton translocating ATPase 100 kDa subunit	O00780 P54641 P54642 P54647 P54648 Q54E04 Q54Z13 Q55AH5 Q55CT1 Q76NU1 Q869V1 Q86A77 Q86AS7 Q8MML6	DDB_G0274141 atp6v1d atp6v1g dvacB nramp nramp1 redB slc11a1 vatA vatB vatC vatD-1 vatD-2 vatE vatF vatH vatM vatP vatg	Dictyostelium discoideum
Synthesis of bile acids and bile salts	Oxysterol-binding protein 11 Oxysterol-binding protein 4 Oxysterol-binding protein 6 Oxysterol-binding protein 8 Putative methylsterol monooxygenase DDB_G0269788 Putative methylsterol monooxygenase DDB_G0270946 Sterol desaturase family protein	Q54ID7 Q54QP6 Q54WK0 Q55D52 Q55D54 Q86HV4 Q86KG4	DDB_G0269788 DDB_G0270946 DDB_G0279611 osbD osbF osbH osbK	Dictyostelium discoideum
Platelet homeostasis	P2X receptor A P2X receptor B P2X receptor C P2X receptor D P2X receptor E	Q54J33 Q54JH4 Q553Y0 Q553Y1 Q86JM7	p2xA p2xB p2xC p2xD p2xE	Dictyostelium discoideum
PDE3B signalling	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 Q23917 Q86H13	Pde4 pde2 pde3 regA	Dictyostelium discoideum
Calnexin/calreticulin cycle	Calnexin Calreticulin Protein disulfide-isomerase 2	Q23858 Q54EN4 Q55BA8	cnxA crtA pdi2	Dictyostelium discoideum
Regulation of TLR by endogenous ligand	Non-histone chromosomal protein 6 homolog UPF0522 protein A UPF0522 protein B UPF0522 protein C	Q54JE7 Q54JE8 Q55BA2 Q55C24	DDB_G0271242 DDB_G0288095 DDB_G0288097 nhp6	Dictyostelium discoideum
Ion homeostasis	Calcium-transporting ATPase PAT1 Calcium-transporting ATPase Inositol 1,4,5-trisphosphate receptor-like protein A NADPH--cytochrome P450 reductase	P54678 Q54HG6 Q55CT1 Q9NA13	DDB_G0289473 iplA patA redB	Dictyostelium discoideum
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase G-protein alpha subunit family protein Guanine nucleotide-binding protein alpha-1 subunit Guanine nucleotide-binding protein alpha-12 subunit Guanine nucleotide-binding protein alpha-2 subunit Guanine nucleotide-binding protein alpha-3 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-5 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein alpha-7 subunit Guanine nucleotide-binding protein alpha-8 subunit Guanine nucleotide-binding protein-like alpha-10 subunit Guanine nucleotide-binding protein-like alpha-11 subunit RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P16051 P16894 P34042 P34043 P34044 P34045 P34046 Q02158 Q54KV6 Q54LD1 Q54M81 Q54S99 Q54UG5 Q54VG1 Q54XJ6 Q556I3 Q55E55 Q55EP5 Q8T130	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 Ga3 gbqA gpa10 gpa11 gpa12 gpaA gpaB gpaC gpaD gpaE gpaF gpaG gpaH gpaJ gpaK gpaL pipA plc	Dictyostelium discoideum
Hyaluronan uptake and degradation	Beta-hexosaminidase subunit A1 Beta-hexosaminidase subunit A2 Beta-hexosaminidase subunit B1 Beta-hexosaminidase subunit B2 beta-N-acetylhexosaminidase	P13723 Q54K55 Q54K56 Q54MU9 Q54SC9	hexa1 hexa2 hexb1 hexb2 nagA nagE	Dictyostelium discoideum	G35674CY
Fructose biosynthesis	Aldose reductase B	Q54NZ7	alrB	Dictyostelium discoideum	G58161NS
Interleukin-4 and Interleukin-13 signaling	C2H2-type domain-containing protein Endoplasmin homolog Signal transducer and activator of transcription A Signal transducer and activator of transcription B Signal transducer and activator of transcription C Signal transducer and activator of transcription Uncharacterized protein Uncharacterized protein	O00910 Q54BD4 Q54GL9 Q54WB7 Q55CI5 Q70GP4 Q86I20 Q9NKX1	DDB_G0270046 DDB_G0279767 DDB_G0290073 dstA dstB dstC dstD grp94 stat5 statA statB statC	Dictyostelium discoideum
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Mannose-P-dolichol utilization defect 1 protein homolog Mannosyltransferase Mannosyltransferase Probable Dol-P-Man Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	B0G0Z6 P0CD61 P90522 Q54QG6 Q54WW9 Q554E2 Q55F69 Q55FZ9 Q7KWM5	alg1 alg12 alg2 alg3 alg6 alg7 alg8 alg9 mntA mpdu1	Dictyostelium discoideum
Recycling of bile acids and salts	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 ABC transporter C family member 10 ABC transporter C family member 12 ABC transporter C family member 3 ABC transporter C family member 5 ABC transporter C family member 8 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54JR2 Q54LE6 Q54P13 Q54RU1 Q54U44 Q55DA7 Q8ST87 Q8T9W1 Q8T9W4 Q9GTN7	abcB2 abcB3 abcB6 abcB7 abcC10 abcC12 abcC3 abcC5 abcC8 tagA tagB tagC tagD	Dictyostelium discoideum
GABA B receptor activation	Metabotropic glutamate receptor-like protein E Metabotropic glutamate receptor-like protein P Metabotropic glutamate receptor-like protein Q	Q54ET0 Q54F54 Q54K09	GluPR grlE grlP grlQ	Dictyostelium discoideum
Effects of PIP2 hydrolysis	Diacylglycerol kinase A Inositol 1,4,5-trisphosphate receptor-like protein A Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P34125 P54644 Q54IF2 Q9NA13	DDB_G0288795 akt dagA dgkA iplA mhcK pkbA	Dictyostelium discoideum
Platelet degranulation	ABC transporter C family member 13 ABC transporter C family member 14 ABC transporter C family member 15 ABC transporter C family member 1 ABC transporter C family member 2 ABC transporter C family member 6 ABC transporter C family member 7 ABC transporter C family member 9 ATPase AAA-type core domain-containing protein Actin-interacting protein 1 Alpha-actinin A Annexin A7 Annexin I BTB domain-containing protein CYFIP-related Rac1 interactor homolog Calmodulin-like protein Calmodulin Calponin-homology (CH) domain-containing protein Calponin-homology (CH) domain-containing protein Calponin-homology (CH) domain-containing protein Chitinase domain-containing protein 1 Cysteine protease Cysteine proteinase 1 EF-hand domain-containing protein Filament-interacting protein Fructose-bisphosphate aldolase GTP-binding protein 1 Gelation factor Interaptin Lysosome membrane protein 2-A Lysosome membrane protein 2-B Lysosome membrane protein 2-C MAGE domain-containing protein Myosin-ID light chain NADH-cytochrome b5 reductase 1 Obg-like ATPase 1 PH domain-containing protein PHD zinc finger-containing protein Peptidase C1A papain C-terminal domain-containing protein Prenylcysteine lyase domain-containing protein Protein transport protein sec1 Putative actin-26 Ras-related protein Rab-32D Saposin A Sec1-like family protein Substrate-adhesion molecule Superoxide dismutase [Cu-Zn] 5 Talin-B Trishanku Tubulin alpha chain Tubulin alpha chain Uncharacterized protein DDB_G0288133 Uncharacterized protein Uncharacterized protein Uncharacterized protein V-SNARE family protein Vesicle transport through interaction with t-SNAREs homolog 1A t-SNARE coiled-coil homology domain-containing protein	O00897 O76329 P02599 P04988 P05095 P13466 P24639 P32255 P54686 Q54CK6 Q54D77 Q54D84 Q54EK2 Q54F16 Q54G42 Q54G70 Q54JD4 Q54K24 Q54K81 Q54KR6 Q54MB6 Q54NC1 Q54NL1 Q54P07 Q54PA3 Q54PW0 Q54Q68 Q54QC8 Q54QM3 Q54R67 Q54RR0 Q54RX2 Q54ST8 Q54TA6 Q54V78 Q54V86 Q54VC1 Q54VJ0 Q54ZW8 Q551W8 Q553C3 Q556T3 Q55CU2 Q55DM8 Q55ET7 Q55FE2 Q55FQ9 Q55FS4 Q75JX5 Q7Z2B8 Q86A67 Q86KD4 Q8I7T3 Q8T2H0 Q8T6H3 Q8T6H8 Q9BKJ9 Q9XYS8	CP1 DDB_G0267974 DDB_G0268156 DDB_G0268758 DDB_G0269600 DDB_G0272218 DDB_G0274385 DDB_G0275765 DDB_G0276317 DDB_G0280565 DDB_G0281889 DDB_G0282287 DDB_G0282859 DDB_G0282977 DDB_G0283859 DDB_G0284679 DDB_G0286055 DDB_G0287201 DDB_G0288133 DDB_G0291191 abcC1 abcC13 abcC14 abcC15 abcC2 abcC6 abcC7 abcC9 abpA abpC abpD act26 actnA actnB aip1 ann7 calA calB camA chid1 cprA cyb5r1 cyri fam49 fba fip-1 fip-2 gtpbp1 lmpA lmpB lmpC mlcD nxnA nxnB rab32D sadA sapA scfd2 sec1 sec1A sodE talB triA tubA vti1 vti1A vti1B wdpA	Dictyostelium discoideum
Passive transport by Aquaporins	Aquaporin A Aquaporin C Aquaporin-B Aquaporin	Q54FQ9 Q54V53 Q54WT8 Q9U8P7	DDB_G0290691 aqpA aqpB wacA	Dictyostelium discoideum
Metabolism of Angiotensinogen to Angiotensins	Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Crystal protein cAMP-regulated D2 protein	P18142 P21837 Q54ET7 Q54N21 Q54WD8 Q86L18	D2 DDB_G0276969 DDB_G0279717 DDB_G0285555 DDB_G0291344 cryS	Dictyostelium discoideum
Zinc influx into cells by the SLC39 gene family	Protein zntA Protein zntD	Q55EA1 Q55FL1	zntA zntD	Dictyostelium discoideum
Acyl chain remodelling of PC	Lysoplasmalogenase homolog Membrane bound O-acyl transferase family protein Patatin family protein Phospholipase B-like protein D	Q54PS7 Q54QX6 Q54XX2 Q86H31	DDB_G0278541 DDB_G0283551 plbD tmem86	Dictyostelium discoideum
DAG and IP3 signaling	Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P54644 Q54IF2	DDB_G0288795 akt dagA pkbA	Dictyostelium discoideum
Cellular hexose transport	Calmodulin-binding protein Major facilitator superfamily (MFS) profile domain-containing protein Sugar transporter SWEET1 Sugar transporter family protein Sugar transporter family protein Uncharacterized protein	Q54CM5 Q54JW5 Q54M69 Q54UC8 Q54Z55 Q7KWK4	DDB_G0276801 DDB_G0277773 DDB_G0281155 DDB_G0286151 slc50a1 symA	Dictyostelium discoideum	G58161NS
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 3beta-hydroxysteroid dehydrogenase Cycloartenol synthase Delta(14)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl diphosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase B Isopentenyl-diphosphate Delta-isomerase Mevalonate kinase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Probable acetyl-CoA acetyltransferase Probable lanosterol 14-alpha demethylase Protein arv1 homolog Putative methylsterol monooxygenase DDB_G0269788 Squalene monooxygenase Squalene synthase	P34135 Q1ZXH9 Q54BK1 Q54BK7 Q54DR1 Q54GD9 Q54PP1 Q54TU9 Q54UH9 Q54YQ9 Q55D54 Q55D85 Q86AD9 Q86AG7 Q86HL5 Q9NH02 Q9NH03	DDB_G0269788 DDB_G0271544 DDB_G0281069 DDB_G0281487 Dipi arv1 cas1 cyp51 erg24 fdfT fps ggps1 hgsB hmgA idi ipi mvd mvk sqle	Dictyostelium discoideum
Surfactant metabolism	ABC transporter A family member 2 ABC transporter A family member 3 ABC transporter A family member 4 ABC transporter A family member 5 ABC transporter A family member 6 Adenosine deaminase 2 Cathepsin D Saposin A Saposin B domain-containing protein	O76856 Q54BT5 Q54PT7 Q54Q68 Q553U5 Q555Z5 Q8T6J1 Q8T6J2 Q8T6J5	ADA2 CatD DDB_G0284339 abcA2 abcA3 abcA4 abcA5 abcA6 ctsD sapA	Dictyostelium discoideum
Detoxification of Reactive Oxygen Species	1-Cys peroxiredoxin Catalase-A Cytochrome c Extracellular superoxide dismutase [Cu-Zn] 2 Extracellular superoxide dismutase [Cu-Zn] 3 Glutathione S-transferase domain-containing protein DDB_G0273153/DDB_G0273923 Glutathione reductase Peroxiredoxin-4 Probable copper chaperone for superoxide dismutase Probable superoxide dismutase [Cu-Zn] 6 Putative glutathione S-transferase alpha-1 Putative glutathione S-transferase alpha-2 Putative glutathione S-transferase alpha-3 Putative glutathione S-transferase alpha-4 Putative glutathione S-transferase alpha-5 Putative thioredoxin-4 Superoxide dismutase [Cu-Zn] 4 Superoxide dismutase [Cu-Zn] 5 Superoxide dismutase [Mn], mitochondrial Superoxide-generating NADPH oxidase heavy chain subunit A Superoxide-generating NADPH oxidase heavy chain subunit B Superoxide-generating NADPH oxidase heavy chain subunit C Thioredoxin domain-containing protein Thioredoxin domain-containing protein Thioredoxin-3	O77229 P29447 Q1ZXE0 Q54F44 Q54F73 Q54G70 Q54N76 Q54NX3 Q54QV7 Q54RN1 Q54RQ1 Q54SE2 Q54TU5 Q54TW8 Q54VI4 Q555L5 Q556G3 Q556P3 Q55BJ9 Q55FF3 Q869N1 Q86AU1 Q86GL4 Q8T137 Q9XYS3	DDB_G0273153 DDB_G0282517 DDB_G0284939 cat catA ccs ccsA cytC gsr gsta1 gsta2-1 gsta2-2 gsta3 gsta4 gsta5 noxA noxB noxC prdx4 prdx5 sod2 sodB sodC sodD sodE sodF trx3 trx4 trxC trxD	Dictyostelium discoideum

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