GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **128** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
N-glycan trimming and elongation in the cis-Golgi	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q54IX1	gnt3	Dictyostelium discoideum
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	Q54CH4 Q54PP9 Q54PQ0 Q54PQ1 Q55EU0	DDB_G0268754 DDB_G0284391 DDB_G0284393 DDB_G0284395 DDB_G0292918	Dictyostelium discoideum	G70323CJ
Toll Like Receptor 4 (TLR4) Cascade	UPF0522 protein A UPF0522 protein B UPF0522 protein C	Q54JE7 Q54JE8 Q55BA2	DDB_G0271242 DDB_G0288095 DDB_G0288097	Dictyostelium discoideum
Antimicrobial peptides	Transglycosylase SLT domain-containing protein UPF0522 protein C	Q54XV8 Q55BA2	DDB_G0271242 DDB_G0278563	Dictyostelium discoideum	G49108TO
ECM proteoglycans	Substrate-adhesion molecule	Q8I7T3	sadA	Dictyostelium discoideum
Fibronectin matrix formation	Substrate-adhesion molecule	Q8I7T3	sadA	Dictyostelium discoideum
Rhesus glycoproteins mediate ammonium transport.	Rhesus-like glycoprotein A Rhesus-like glycoprotein B	Q8I0L6 Q9NIV0	rhgA rhgB	Dictyostelium discoideum
Zinc influx into cells by the SLC39 gene family	Protein zntA Protein zntD	Q55EA1 Q55FL1	zntA zntD	Dictyostelium discoideum
Hyaluronan biosynthesis and export	Protein DDB_G0287365 Transmembrane protein	Q54KF6 Q55D62	DDB_G0270636 DDB_G0287365	Dictyostelium discoideum	G35674CY
IRE1alpha activates chaperones	Probable serine/threonine-protein kinase ireA	Q55GJ2	ireA	Dictyostelium discoideum
DAG and IP3 signaling	Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P54644 Q54IF2	DDB_G0288795 akt dagA pkbA	Dictyostelium discoideum
Response to elevated platelet cytosolic Ca2+	Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P54644 Q54IF2	DDB_G0288795 akt dagA pkbA	Dictyostelium discoideum
PI3K/AKT Signaling	Probable serine/threonine-protein kinase DDB_G0288795 Probable serine/threonine-protein kinase pdkA Protein LST8 homolog Protein pianissimo A RAC family serine/threonine-protein kinase homolog Ras-interacting protein RIP3 Serine/threonine-protein kinase tor Thioesterase domain-containing protein	O77203 P54644 Q54D08 Q54IF2 Q54TW2 Q556W3 Q86C65 Q9Y0C9	DDB_G0273293 DDB_G0288795 DG1117 akt amiA dagA lst8 pdkA pia piaA pkbA rip3 ripA tor	Dictyostelium discoideum
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 Q54CI0 Q55G89	DDB_G0268520 ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum	G03934XO G25577BM G28233ME G51034LA G86419OL
Digestion	Pirin family protein	Q54EK6	DDB_G0291472	Dictyostelium discoideum
Hydrolysis of LPC	Phospholipase B-like protein D	Q54PS7	plbD	Dictyostelium discoideum
Events associated with phagocytolytic activity of PMN cells	Peroxinectin A	Q6TMK4	poxA	Dictyostelium discoideum
Thyroxine biosynthesis	Peroxinectin A Superoxide-generating NADPH oxidase heavy chain subunit A Superoxide-generating NADPH oxidase heavy chain subunit B Superoxide-generating NADPH oxidase heavy chain subunit C	Q54F44 Q6TMK4 Q86GL4 Q9XYS3	noxA noxB noxC poxA	Dictyostelium discoideum
Role of phospholipids in phagocytosis	PA-phosphatase related-family protein DDB_G0271516 PA-phosphatase related-family protein DDB_G0275547 PA-phosphatase related-family protein DDB_G0284367 Phospholipase D A Phospholipase D B Phospholipase D C Phospholipase D Y Phospholipase D Z Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog phospholipase D	P54644 Q54IF2 Q54K50 Q54PR7 Q54Q49 Q54SA1 Q54UK0 Q54WR4 Q54Z25 Q86AF0 Q8MXL9	DDB_G0271516 DDB_G0275547 DDB_G0284155 DDB_G0284367 DDB_G0288795 akt dagA pkbA pld1 pld3 pldA pldB pldC pldY pldZ	Dictyostelium discoideum
Platelet homeostasis	P2X receptor A P2X receptor B P2X receptor C P2X receptor D P2X receptor E	Q54J33 Q54JH4 Q553Y0 Q553Y1 Q86JM7	p2xA p2xB p2xC p2xD p2xE	Dictyostelium discoideum
Synthesis of bile acids and bile salts	Oxysterol-binding protein 11 Oxysterol-binding protein 4 Oxysterol-binding protein 6 Oxysterol-binding protein 8 Putative methylsterol monooxygenase DDB_G0269788 Putative methylsterol monooxygenase DDB_G0270946 Sterol desaturase family protein	Q54ID7 Q54QP6 Q54WK0 Q55D52 Q55D54 Q86HV4 Q86KG4	DDB_G0269788 DDB_G0270946 DDB_G0279611 osbD osbF osbH osbK	Dictyostelium discoideum
Regulation of TLR by endogenous ligand	Non-histone chromosomal protein 6 homolog UPF0522 protein A UPF0522 protein B UPF0522 protein C	Q54JE7 Q54JE8 Q55BA2 Q55C24	DDB_G0271242 DDB_G0288095 DDB_G0288097 nhp6	Dictyostelium discoideum
Nitric oxide stimulates guanylate cyclase	NADPH--cytochrome P450 reductase	Q55CT1	redB	Dictyostelium discoideum
Ion influx/efflux at host-pathogen interface	Metal transporter nramp1 homolog	Q869V1	nramp nramp1 slc11a1	Dictyostelium discoideum
ROS and RNS production in phagocytes	Metal transporter nramp1 homolog NADPH--cytochrome P450 reductase V-ATPase proteolipid subunit C-like domain-containing protein V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit d Vacuolar proton translocating ATPase 100 kDa subunit	O00780 P54641 P54642 P54647 P54648 Q54E04 Q54Z13 Q55AH5 Q55CT1 Q76NU1 Q869V1 Q86A77 Q86AS7 Q8MML6	DDB_G0274141 atp6v1d atp6v1g dvacB nramp nramp1 redB slc11a1 vatA vatB vatC vatD-1 vatD-2 vatE vatF vatH vatM vatP vatg	Dictyostelium discoideum

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