GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **597** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Translesion Synthesis by POLH	DNA polymerase eta FI03607p GEO08380p1 GH17761p LD35209p Nuclear protein localization protein 4 homolog Polyubiquitin Proliferating cell nuclear antigen Protein with SprT-like domain at the N terminus Replication factor A protein 2 Replication factor C 38kD subunit, isoform A Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication protein A 70 kDa DNA-binding subunit Transitional endoplasmic reticulum ATPase TER94 Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG69 P15357 P17917 P35600 P53034 Q24492 Q7KN62 Q9U9Q1 Q9VBP9 Q9VIH1 Q9VKW3 Q9VMD4 Q9VNX1 Q9VTF9 Q9VX15 Q9VXU6 Q9VYW3 Q9W418 R9PY16	153194_at BcDNA:LD06837 BcDNA:RH55360 CG16947-RA CG18282 CR11700 CR32744 D-SSB DNApol-eta DNApolH DRFC DRP-A DmRFC2 DmRFC3 DmRFC5 DmRP-A DmRPA DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG15220 Dmel\CG16947 Dmel\CG32744 Dmel\CG5313 Dmel\CG6258 Dmel\CG8142 Dmel\CG9203 Dmel\CG9273 ESTS:143G11T ESTS:199A6T Gnf1 Npl4 PCNA PCNA1 PolH RFC2 RP-A RPA RPA 30 kDa RPA1 RPA2 RPA3 RPA30 Rchy1 RfC RfC3 RfC38 RfC4 RfC40 Rfc3 Rfc37 Rfc38 RpA-30 RpA2 RpS27A Ssb-30 TER94 UB UB3-D UBI-F80 UFD1L Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Ufd1 Ufd1-like VCP anon-EST:Posey20 anon-sts41 dPoleta dRP-A dRPA2 drad30A fs(1)1182 fs(1)A1182 l(1)G0241 l(2)k13807 l(2)rfc38 mh mus209 n(2)k13807 poly-ub rfc3 rfc38	Drosophila melanogaster (fruit fly)
Termination of translesion DNA synthesis	DNA polymerase epsilon catalytic subunit 1 DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 GEO08380p1 LD35209p Polyubiquitin Proliferating cell nuclear antigen Replication factor A protein 2 Replication factor C 38kD subunit, isoform A Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication protein A 70 kDa DNA-binding subunit ubiquitinyl hydrolase 1	P0CG69 P17917 P35600 P53034 Q24492 Q9U9Q1 Q9V444 Q9VCN1 Q9VIH1 Q9VKW3 Q9VRQ7 Q9VX15 Q9VYW3 Q9W117 Q9W256	153194_at BcDNA:LD06837 BcDNA:RH55360 CG30421-RA CG3872 CG9189 CHRAC CHRAC14 Chrac-14 D-SSB DNApol-epsilon DNApol-epsilon255 DNApol-epsilon58 DNApolE2 DNApolE3 DNApolE4 DRFC DRP-A DUSP31 DmRFC2 DmRFC3 DmRFC5 DmRP-A DmRPA Dmel\CG15220 Dmel\CG30421 Dmel\CG5313 Dmel\CG6258 Dmel\CG8142 Dmel\CG9273 Gnf1 Mes4 NF-Yc PCNA PCNA1 PolE1 PolE2 PolE4 Polepsilon Q9W117 RFC2 RP-A RPA RPA 30 kDa RPA1 RPA2 RPA3 RPA30 RfC RfC3 RfC38 RfC4 RfC40 Rfc3 Rfc37 Rfc38 RpA-30 RpA2 Ssb-30 USP43 Ubi-m Ubi-p63E Usp15 Usp15-31 Usp31 dRP-A dRPA2 l(1)G0241 l(2)k13807 l(2)rfc38 l(3)pl10 l(3)pl10R mary mus209 n(2)k13807 rfc3 rfc38	Drosophila melanogaster (fruit fly)
Formation of the activated receptor complex	Cytokine receptor FI03911p Tyrosine-protein kinase hopscotch Unpaired 2 Unpaired protein	O96525 Q24592 Q59E38 Q9VWE0 Q9VWX2	CG15062 CG15062/CG5963 CG5963 Dmel\CG33542 Dmel\CG5988 HD-160 UPD2 UPD3 Upd Upd-3 Upd-like Upd2 Upd2/Leptin Upd3 cg15062 cg5963 cg5988 dome hop od odsy os sy unpaired upd upd 3 upd-2 upd-3 upd1 upd2 upd3 upd3-RB	Drosophila melanogaster (fruit fly)
Dephosphorylation by PTP61F phosphatases	Cytokine receptor FI03911p Signal transducer and transcription activator Tyrosine-protein kinase hopscotch Unpaired 2 Unpaired protein	O96525 Q24151 Q24592 Q59E38 Q9VWE0 Q9VWX2	CG15062 CG15062/CG5963 CG5963 Dmel\CG33542 Dmel\CG5988 HD-160 MARE Stat Stat92E UPD2 UPD3 Upd Upd-3 Upd-like Upd2 Upd2/Leptin Upd3 cg15062 cg5963 cg5988 dome hop mrL od odsy os sy unpaired upd upd 3 upd-2 upd-3 upd1 upd2 upd3 upd3-RB	Drosophila melanogaster (fruit fly)
Formation of the activated STAT92E dimer and transport to the nucleus	Cytokine receptor FI03911p Signal transducer and transcription activator Tyrosine-protein kinase hopscotch Unpaired 2 Unpaired protein	O96525 Q24151 Q24592 Q59E38 Q9VWE0 Q9VWX2	CG15062 CG15062/CG5963 CG5963 Dmel\CG33542 Dmel\CG5988 HD-160 MARE Stat Stat92E UPD2 UPD3 Upd Upd-3 Upd-like Upd2 Upd2/Leptin Upd3 cg15062 cg5963 cg5988 dome hop mrL od odsy os sy unpaired upd upd 3 upd-2 upd-3 upd1 upd2 upd3 upd3-RB	Drosophila melanogaster (fruit fly)
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glucose transporter type 1 Glutathione S transferase O1 Glutathione S transferase O2, isoform A Glutathione S transferase O3 LD30822p Pyrimidodiazepine synthase cytochrome-b5 reductase	Q8IRI6 Q9V4N3 Q9VH02 Q9VSL2 Q9VSL3 Q9VSL5 Q9VSL6 Q9VWK8	CG6293-RA CG6673-A CG6673-B CG6673A CG6673B Cyt-b5 DmGSTO1 DmGSTO2a DmGSTO2b DmGSTO3 Dmel\CG6293 Dmel\CG6662 Dmel\CG6673 Dmel\CG6776 Dmel\CG7914 GSTO1 GSTO2 GSTO2a GSTO2b GSTO3 Glut1 GstO1 GstO2 GstO3 T14 anon-EST:Posey29 dGstO1 gsto2 se	Drosophila melanogaster (fruit fly)
G alpha (12/13) signalling events	Cysts, isoform C Dopamine/Ecdysteroid receptor, isoform A Dynamin associated protein 160, isoform D Ephexin, isoform D FI17866p1 GH12381p Gbeta5 Guanine nucleotide-binding protein subunit alpha homolog Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma-1 Guanine nucleotide-binding protein subunit gamma-e Guanine nucleotide-binding protein subunit gamma IP13425p LD43457p Pebble, isoform B Plexin-B Protein son of sevenless Protein still life, isoform SIF type 1 Protein vav Ras-like GTP-binding protein Rho1 Rho GTPase activating protein at 1A, isoform E Rho guanine nucleotide exchange factor 2, isoform D Rho guanine nucleotide exchange factor 3, isoform L Rho-associated protein kinase Rho-type guanine nucleotide exchange factor, isoform F Trio, isoform A Tyramine receptor Tyrosine-protein kinase Btk Uncharacterized protein, isoform A Uncharacterized protein, isoform B Uncharacterized protein, isoform B Uncharacterized protein, isoform C Uncharacterized protein, isoform C Uncharacterized protein, isoform C	A0A0B4K6L3 A0A0B4K838 A1ZAN6 A1ZAQ3 A1ZAQ4 A1ZBA1 A8DZ19 M9ND00 M9PBE1 M9PHU0 P08630 P25157 P26308 P26675 P29829 P38040 P48148 P91621 Q7K4E0 Q7KVD1 Q8IQ97 Q9NFZ3 Q9NHV9 Q9V4A7 Q9VBG4 Q9VEG1 Q9VEG2 Q9VVC6 Q9VVJ1 Q9VW85 Q9VXE3 Q9VZD1 Q9W0S2 Q9W3J1 X2JC00	0083/20 0293/09 0368/10 0542/03 0959/14 1372/03 1386/06 38C.40 ARHGEF7 BCR BEST:LD36950 BcDNA:GH03693 BcDNA:GH27361 Btk Btk29A CG10412 CG10416 CG12183 CG1225 CG12432 CG13811 CG13812 CG13881 CG13882 CG13883 CG14060 CG14318 CG15612 CG15613 CG15844 CG17617 CG17960 CG18430 CG30115-RE CG32223 CG3799 CG40453 CG42348 CG42377 CG42378 CG5503 CG7323 CG7397 CG8557 CG9208 CHED-related CTR DAP-160 DAP160 DROK DRhk DRhoGEF DRhoGEF2 DRok DTrio Dap160 Dap160/intersectin DmCG16766 DmCG7431 DmDopEcR DmTAR2 Dmel\CG10043 Dmel\CG10188 Dmel\CG10763 Dmel\CG1099 Dmel\CG12290 Dmel\CG15611 Dmel\CG16766 Dmel\CG18214 Dmel\CG18314 Dmel\CG30115 Dmel\CG30440 Dmel\CG30456 Dmel\CG40494 Dmel\CG42665 Dmel\CG42674 Dmel\CG43102 Dmel\CG43324 Dmel\CG43658 Dmel\CG43976 Dmel\CG7431 Dmel\CG7497 Dmel\CG8114 Dmel\CG9635 Dmel\CG9774 DopECR DopEcR Dp114/Cysts Dp114RhoGEF DrhoGEF DrhoGEF2 DrhoGEF3 DrmTR Drok DrtGEF ECT2 EG:23E12.2 EG:23E12.5 Ect-2 Exn Exn-RD G-beta-5 G1 GEF GEFmeso GNB5 G[[beta5]] G[[beta]] Gb13F Gb76C Gbe Gbeta Gbeta 5 Gbeta13F Gbeta5 Gbeta76C Gbetae Gbetagamma Gef2 Ggamma1 Ggamma30A Ggammae M89 MRLC PBL Pbl Pbl/Ect2 Peb Pix PlexB RG2 ROCK ROCK-1 ROCK1 ROCK2 ROK ROKalpha/beta Rhk Rho-GEF2 Rho/RacGEF Rho1 RhoGAP RhoGAP1A RhoGEF RhoGEF2 RhoGEF3 RhoGF2 RhoGef2 RhoK Rock Rok Rok/ROCK RtGEF Sos Src2 Src29A Su(Rho1)2B T2 TAR2 TAR3 TR TRIO Tec29 Trio TyrR TyrRII TyrRIII UNC-73/Trio Vav anon-WO0170980.124 anon-WO0170980.125 anon-WO0170980.139 anon-WO0170980.140 anon-WO0170980.49 anon-WO0170980.50 anon-WO0170980.82 anon-WO0170980.83 anon-WO0170980.88 anon-WO0170980.89 anon-WO0172774.22 anon-WO0172774.25 beta-PIX betaPIX cta cyst dPIX dPix dROK dRhoGEF dRhoGEF2 dRok dTrio dap160 dop dpix drok exn l(2)04291 l(3)036810 l(3)09645 l(3)6D104 l(3)S036810 l(3)S095914 l(3)S137203 l(3)S138606 l(3)S[1372/3] l(3)S[1386/06] l(3)trio lincRNA.S7704 noncoding_4110 p160 pbl pix rhoGAP1A rhoGEF rhoGEF2 rhoGEF3 rhogef2 rok rok-RA rtGEF shar sif trio tyrR tyrRII	Drosophila melanogaster (fruit fly)
Miscellaneous transport and binding events	Cystinosin homolog GH11935p Leucine-rich repeat protein soc-2 homolog Protein hu-li tai shao Spichthyin, isoform B Uncoordinated 115a, isoform B Uncoordinated 115b, isoform C	E1JIH3 M9PD12 Q02645 Q8INN6 Q8SY53 Q9VCR7 Q9VEK6	CG17119 CG9489 Dmel\CG12292 Dmel\CG31332 Dmel\CG31352 Dmel\CG7830 Dunc-115 MagT1 OST Ostgamma Spict Sur-8 Unc-115a Unc-115b anon-WO0140519.21 anon-WO0140519.9 dMagT1 dunc-115 hts spg6 spict unc-115	Drosophila melanogaster (fruit fly)
Mitotic Prophase	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B Mushroom body defect, isoform H	P20439 P23572 Q8IR55	Cdk1 CycB Dmel\CG12047 KS63 Mud NuMA NuMa cdc2 mud	Drosophila melanogaster (fruit fly)
RNA polymerase II transcribes snRNA genes	Cyclin K, isoform A Cyclin-T Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerase II subunit Rpb4 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 GEO07843p1 GEO11084p1 GH07456p GH11150p General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Integrator complex subunit 10 Integrator complex subunit 11 Integrator complex subunit 12 Integrator complex subunit 14 Integrator complex subunit 1 Integrator complex subunit 2 Integrator complex subunit 3 Integrator complex subunit 4 Integrator complex subunit 5 Integrator complex subunit 6 Integrator complex subunit 7 Integrator complex subunit 8 Integrator complex subunit 9 LD11480p LD16387p LD18233p Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PSEA-binding protein 45kD Phosphorylated adapter RNA export protein Platelet-activating factor acetylhydrolase IB subunit beta homolog Protein asunder Protein nubbin Protein suppressor of sable RNA polymerase II elongation factor Ell RNA polymerase II subunit A C-terminal domain phosphatase SSU72 RPB5 homolog SOSS complex subunit B homolog Serrate RNA effector molecule homolog Sp1-like factor for pairing sensitive-silencing, isoform B TATA-box-binding protein TBP-related factor Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription factor btd Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 8 Transcription initiation factor TFIID subunit 9 Uncharacterized protein, isoform A Uncharacterized protein, isoform C snRNA-activating protein complex subunit 3	A0A0B4KHC8 A1Z7P3 A1Z9W4 A1ZAK1 O17432 O96433 O96880 O96881 O97183 P04052 P08266 P20227 P22293 P29052 P31368 P36958 P41900 P49846 P49847 P49906 P52654 P52656 Q05913 Q24216 Q24266 Q24320 Q27272 Q27896 Q6IGE3 Q7JUY8 Q7JZF5 Q7K4N3 Q7PLS8 Q95TS5 Q961D1 Q9TVQ5 Q9V3L6 Q9V460 Q9V9K7 Q9VAH9 Q9VBB3 Q9VC49 Q9VCN9 Q9VEA5 Q9VEX5 Q9VF25 Q9VFB5 Q9VFS6 Q9VHX0 Q9VIP1 Q9VJE4 Q9VM17 Q9VNZ3 Q9VPY0 Q9VT41 Q9VT91 Q9VW51 Q9VWE4 Q9VWY6 Q9VX31 Q9VXP4 Q9VZM7 Q9W039 Q9W1C5 Q9W3E1 Q9W485 X2JAA3	152117_at 38B.15 Ars2 Asun BEST:CK01830 BEST:GH22533 BEST:LD28511 BG:DS00941.10 BTF1 CD 7 CDK7 CDK9 CG11508 CG42516-RA CG5181 CG6572 Can Cbp20 Cbp80 Cdk7 Cdk9 CycK CycT D-rpII33 DMPBP49 DmCDK7 DmCdk7 DmMO15 DmMo15 DmP-TEFb DmPBP DmPBP45 DmPBP49 DmPBP95 DmRPB5 DmSNAP190 DmSNAP43 DmSNAP50 DmSNAPc Dmcdk7 Dmel\CG10228 Dmel\CG10415 Dmel\CG10756 Dmel\CG11246 Dmel\CG11979 Dmel\CG1276 Dmel\CG14216 Dmel\CG15160 Dmel\CG15218 Dmel\CG2702 Dmel\CG31155 Dmel\CG3319 Dmel\CG34186 Dmel\CG42515 Dmel\CG4448 Dmel\CG5179 Dmel\CG5669 Dmel\CG6577 Dmel\CG7885 Dmel\CG8069 Dmel\CG9018 Dmel\CG9597 E[[S]] Ell FBgn0035318 Inr-a IntS1 IntS10 IntS11 IntS12 IntS13 IntS14 IntS2 IntS3 IntS4 IntS5 IntS6 IntS7 IntS8 IntS9 Mat89Bb Mo15 OCT1 P-TEF P-TEFb PCF11 POU-19 PTefb Paf-AHalpha Pbp45 Pbp49 Pbp95 Pcf11 Pcf11-RA Phax Pol II Pol II RPII33 PolII PolIIo Polr2A Polr2B Polr2C Polr2D Polr2E Polr2F Polr2G Polr2H Polr2I Polr2J Polr2K Polr2L RNA Pol II RNA pol II RNA polII RNAP RP140 RPB1 RPB12 RPB2 RPB3 RPB5 RPB6 RPB7 RPB8 Rbp3 RpABC14 RpII140 RpII15 RpII18 RpII215 RpII33 Rpb10 Rpb11 Rpb12 Rpb3 Rpb4 Rpb5 Rpb7 Rpb8 Rpll33 SNAP43 Spps Spt5 Ssu72 Su(Tpl) TAF TAF13 TAF18 TAF30-BETA TAF40 TAF5 TAF5L TAF80 TAFII40 TAF[[II]] TAF[[II]]18 TFIID TFIIE TFIIE-L TFIIEalpha TFIIEbeta TFIIF30 TFIIbeta TWN Taf11 Taf13 Taf18 Taf5 Taf5L Taf6 Taf60 Taf8 Taf9 Tbp TfIIA-L TfIIA-S TfIIB TfIIE TfIIE-alpha TfIIE-beta TfIIEa TfIIEalpha TfIIEbeta TfIIFalpha TfIIFbeta Trf WDA WFA WSB-1 WSB1 Wda anon-WO0118547.146 anon-WO0118547.359 br17 btd can cdk-7 cdk7 cdk9 cycK dCdk7 dPHAX dPcf11 dRpb7 dSsu72 dTAF5L dTAF[[II]]18 dTAF[[II]]80 dTFIIE-L dTFIIE-S dTFIIEL dTFIIES dWda defl dmTAF5b e(y)1 l(1)G0060 l(1)G0095 l(2)34Dg l(2)br17 l(2)k05605 l(2)k08015 l34Dg nub omd ovary2 p40[MO15] pcf11 pdm-1 pds pol II polII prod rpII33 rpb3 spt4 su(s) su(sable) taf13 taf5L wda	Drosophila melanogaster (fruit fly)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Cyclin K, isoform A Cyclin-C Cyclin-T Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 Furin-like protease 1, isoforms 1/1-X/2 GH17761p Menin Mitogen-activated protein kinase ERK-A Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin RE32990p Retinoblastoma family protein Sp1-like factor for pairing sensitive-silencing, isoform B Transcription factor Dp Transcription factor E2F2 Transcription factor btd Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0B4KHC8 A0A6H2EEY2 O17432 O62609 O77051 O96433 O96660 P0CG69 P15357 P25008 P26016 P40417 Q24266 Q24318 Q24472 Q961D1 Q9VF04 Q9VM47 Q9VT57 Q9W418 R9PY16	1883 CDK9 CG18282 CG33266 CLND CR11700 CR32744 Cdk8 Cdk9 CycC CycK CycT DAD DSMAD2 DSmad2 Dad DmP-TEFb DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG13778 Dmel\CG15218 Dmel\CG1775 Dmel\CG2262 Dmel\CG32744 Dmel\CG5083 Dmel\CG5179 Dmel\CG5201 Dmel\CG5669 Dp E(zen)3 E2f2 EP(3)3196 EP3196 ERKa ESTS:143G11T ESTS:199A6T Fur1 MAPK MED MEN1 Med Medea Menin Menin1 Mnn Mnn1 P-TEF P-TEFb PTefb RB RBF2 RBf2 Rbf Rbf2 RpS27A SMAD2 SMAD4 SMOX Sad Smad Smad2 Smad4 SmoX Smox Spps UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin anon-EST:Posey121 anon-EST:fe1F5 anon-sts41 btd cdk9 cycK dSMAD2 dSmad2 dSmad4 dad dsmad2 l(1)G0348 l(3)11m-254 l(3)12m-137 l(3)SG36 l(3)SG70 l(3)XIIm137 l(3)j1E4 med medea menin mnn1 poly-ub rbf2 rl sad smad2 smad4 smox ted tmp	Drosophila melanogaster (fruit fly)
RUNX3 regulates p14-ARF	Cyclin D, isoform D Histone deacetylase 4, isoform G Homeotic protein female sterile IP14417p1 Maverick Protein big brother Protein decapentaplegic Protein lozenge Ras-like protein 1 Runt related A, isoform D Runt related B Segmentation protein Runt histone acetyltransferase	M9MS40 M9PHQ2 M9PI08 P07713 P08646 P13709 P22814 Q24040 Q7KUZ5 Q9V4E6 Q9VCG6 Q9VRA9 Q9W349	Bgb CBP CBP/p300 CBP_ CDI3 CG13597-RA CG1379 CG15321 CG15453 CG15454 CG15455 CYCD Cbp Cdi3 Crbp Cyc D Cyc-D CycD DHDAC4 DmcycD Dmel\CG13597 Dmel\CG15319 Dmel\CG1770 Dmel\CG1901 Dmel\CG34145 Dmel\CG42267 Dmel\CG9096 GC1770 HDAC HDAC4 HDAC4a MAV Mav Nej Nejire P300 Ras1 Ras85D RunxA RunxB TGF-b anon-WO0147981.11 anon-WO03040301.89 cbp cdi3 cycD cyclin D cyclinD dCBP dCycD dHDAC4 dKAT3 dmCBP dmHDA405 dpp fs(1)h fsh hdac4 l(1)G0112 l(1)G0350 l(1)G0470 lz mav nej nej CBP p300 p300/CBP run tBRD-1 tBrd-1 tbrd-1	Drosophila melanogaster (fruit fly)
Transcriptional regulation by RUNX2	Cyclin D, isoform D Cyclin-dependent kinase 1 Cyclin-dependent kinase 4, isoform A G2/mitotic-specific cyclin-B LD34192p Protein big brother Protein lozenge Runt related A, isoform D Runt related B Segmentation protein Runt Sox100B	M9PI08 P20439 P22814 P23572 Q24040 Q7K306 Q7KUZ5 Q9VA17 Q9VRA9 Q9W349 Q9W4H8	8-6 Bgb CDI3 CDK4 CDK4/6 CG12098 CG1379 CG15453 CG15454 CG15455 CG18674 CT6009 CYCD Cdi3 Cdk1 Cdk4 Cdk4/6 Cyc D Cyc-D CycB CycD DmCdk4 DmcycD Dmel\CG15552 Dmel\CG2984 Dmel\CG34145 Dmel\CG42267 Dmel\CG5072 Dmel\CG9096 PP2C PP2C1 Pk53C Pk?7 Pp2C1 RunxA RunxB SOX100B SOXE Sox100 Sox100B Sox9 SoxB anon-WO03040301.132 cdc2 cdi3 cdk cdk4 cdk4/6 cycD cyclin D cyclinD dCdk4 dCycD dSox9 dpp2c1 l(2)05428 l(2)0671 l(2)k06503 l(2)s4639 l(2)sh0671 lz run	Drosophila melanogaster (fruit fly)
Activation of the phototransduction cascade	Cyclic nucleotide-gated cation channel subunit A Cyclic nucleotide-gated ion channel subunit B, isoform A Uncharacterized protein, isoform E	A0A4P7VAE4 Q24278 Q9W2D5	CG13530 CG3536 Cncbeta Cng CngA CngB Dmel\CG17922 Dmel\CG42260 dCNCbeta dmCNG4 dmCNGB lincRNA.378	Drosophila melanogaster (fruit fly)
Gastrin-CREB signalling pathway via PKC and MAPK	Cyclic AMP response element-binding protein B Mitogen-activated protein kinase ERK-A Ribosomal protein S6 kinase II, isoform A	P40417 Q9VR61 Q9VWW0	CrebB CrebB-17A D-RSK Dmel\CG17596 ERKa MAPK RSK Rsk S6KII S6kII dRSK dRsk ign rl rsk rsk2	Drosophila melanogaster (fruit fly)
AKT phosphorylates targets in the nucleus	Cyclic AMP response element-binding protein B Forkhead box protein O Probable nuclear hormone receptor HR38 RAC serine/threonine-protein kinase Ribosomal protein S6 kinase Serine/threonine-protein kinase S6KL	P49869 Q8INB9 Q94533 Q95V55 Q9VWQ2 Q9VWW0	10539 7-10 7084 Afx Akt Akt1 Bin4 CrebB CrebB-17A DS6K Dmel\CG10539 Dp70S6k Dp70[s6k] Dp70s6k Hr38 NR4A4 Pk17E Pk64F Pk?6 S6 S6 K S6K S6K1 S6KL S6k S6k-RA d-S6K dP70S6K dS6K dS6K1 dS6k dp70[S6k] dp70s6k dps6k ds6k foxo fs(3)07084 l(3)07084 p-S6K p70 S6K p70/S6K p70S6K p70S6k p70[S6 kinase] p70[S6K] p70[S6k] p70[S6kinase] p70s6K pS6K s6k s6k11	Drosophila melanogaster (fruit fly)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Cyclic AMP response element-binding protein B Dacapo Exportin-1 Forkhead box protein O Mitogen-activated protein kinase ERK-A RAC serine/threonine-protein kinase	P40417 Q7JNL9 Q8INB9 Q95V55 Q9TVM2 Q9VWW0	Afx Akt Akt1 CDI4 CDKN2B CIB1 Cdi4 CrebB CrebB-17A Crm1 DAP Dac Dacapo Dap Decapo Dmel\CG1772 E(Sev-CycE)2B ERKa MAPK P15 cdi4 dap dap-RA emb foxo l(2)04454 p21 p21[dacapo] p27 p27[Dap] p27cip/kip rl	Drosophila melanogaster (fruit fly)
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP Epidermal growth factor receptor GH17761p Heat shock protein 83 Hsp90 co-chaperone Cdc37 Low-density lipoprotein receptor-related protein Polyubiquitin Protein cueball Protein vein Tyrosine-protein kinase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A1Z9D7 P02828 P04412 P0CG69 P15357 Q24276 Q8INJ8 Q94918 Q95RU0 Q9VAQ0 Q9W418 Q9XYW6 R9PY16	Arr BEST:CK00539 CG17309 CG18282 CG32852 CHIP CK00539 CR11700 CR32744 CSK CT15575 CUL5 Cdc37 Chip Csk Cul-5 Cul-5-RA Cul5 Cullin5 DCsk DER Dm Arr DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG1401 Dmel\CG32744 Dmel\CG42317 Dmel\CG5203 Dmel\CG5912 E(sev)3B ESTS:143G11T ESTS:199A6T Egfr Hsp82 Hsp83 Hsp90 Irp6 LRP LRP/Arr LRP5/6 LRP6 RpS27A STUB1 Src Stub1 UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin anon-sts41 arr arr-RA c-erbB csk cue cul-5 cul5 d-Csk dCHIP dCSK dCsk dcsk ddd flik l(2)k08131 l(3)S017909 l(3)j1D8 poly-ub top vn	Drosophila melanogaster (fruit fly)
Regulation of Complement cascade	Corin, isoform B Notopleural, isoform A Peptidase S1 domain-containing protein Serine protease filzig Serine proteinase stubble Uncharacterized protein, isoform A trypsin trypsin trypsin	A1Z709 A1Z7M3 A1Z7M5 A1Z7M7 A8DY75 B7YZU2 Q05319 Q8IRR3 Q9W453	CG11824 CG6048-RA CG8181 Corin Dmel\CG13744 Dmel\CG2105 Dmel\CG32755 Dmel\CG34350 Dmel\CG6048 Dmel\CG8170 Dmel\CG8172 Np SP108 SP233 SP32 SP54 SP59 SP67 SP75 Sb Sb-sbd c-SP32 c-SP67 cSP32 cSP54 cSP59 cSP67 corin flz lint np	Drosophila melanogaster (fruit fly)
Metal ion SLC transporters	Copper transport protein FI23527p1 Protein Malvolio Uncharacterized protein, isoform C Zinc transporter 63C, isoform F	A8JV32 M9NE97 M9PEG6 P49283 Q9VPE3	BcDNA:RH42635 CG1521 CG32714 CG5130-RA Ctr1A DmCtr1A Dmel\CG17723 Dmel\CG33181 Dmel\CG3977 Dmel\CG5130 Mvl ZNT63C ZNT77C ZnT1 ZnT63 ZnT63C ZnT77C anon-WO0118547.435 cg17723 cg5130 ctr1A dZNT1 dZNT63C dZnT1 dZnT1h dZnT63C dZnT77C	Drosophila melanogaster (fruit fly)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Connector of kinase to AP-1, isoform E Epidermal growth factor receptor Estrogen-related receptor splice variant FI23523p1 Fibroblast growth factor receptor homolog 1 Fibroblast growth factor receptor homolog 2 Fibroblast growth factor Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Knirps-related protein LD28763p LP05116p Low-density lipoprotein receptor-related protein PDGF- and VEGF-receptor related, isoform J PI-3 kinase Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform G Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl Phosphatidylinositol 5-phosphate 4-kinase, isoform A Pi3K21B, isoform B Protein cueball Protein daughter of sevenless Protein embryonic gonad Protein vav Protein vein RAC serine/threonine-protein kinase Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit Serine/threonine-protein phosphatase PP2A Stumps, isoform E Tyrosine-protein kinase Src64B Uncharacterized protein, isoform B Well-rounded, isoform B Widerborst, isoform H Zygotic gap protein knirps	A0A6F7R657 A0A6M3Q9L5 A1Z9D7 D3DML3 E1JHB7 P00528 P04412 P10734 P13054 P15370 P23696 P36179 P91634 Q07407 Q08012 Q09147 Q7KTZ2 Q8IN89 Q8INB9 Q8SXX1 Q8WS79 Q94918 Q95RU0 Q9NHV9 Q9VDT9 Q9VFI0 Q9VLL4 Q9VV98 Q9VWP6 Q9VXB7 Q9VZZ9 Q9W2R3 Q9XTN2	0318/07 0837/10 5836 8222 Akt Akt1 Arr B' B'/PR61 B56-1 B56-2 BEST:CK00539 BEST:LD02456 BNL BcDNA:GM05554 BcDNA:LD34343 Bnl Branchless C CG 7913 CG13398-RA CG17281 CG18485 CG3375 CG4724 CG7901 CK00539 CKA CT15575 CT24332 Cka Cka-RB DER DFGF DOF DP110 Dcka Derr Dm Arr DmBnl DmVEGF-1 DmVEGFR Dmel\CG13398 Dmel\CG17471 Dmel\CG2699 Dmel\CG31317 Dmel\CG32568 Dmel\CG3682 Dmel\CG4141 Dmel\CG4608 Dmel\CG5643 Dmel\CG5912 Dmel\CG7103 Dmel\CG7392 Dmel\CG7404 Dmel\CG7913 Dmel\CG8222 Dmel\CG9701 Dmp110 Dof Dof/stumps/heartbroken Dp110 Dp110/PI3K Dp60 Dpp110 E(sev)2B EP1624 EP3559 ERR Egfr FGF FR1 FR2 Grb2 HD-311 Hbr Hbr/Dof IRS Irp6 LD02456 LRP LRP/Arr LRP5/6 LRP6 NR0A1 NR0A2 NR0A3 NR3B4 P1740 P60 PI(3)K PI-3 kinase PI-3-K PI3 kinase PI3'K PI3K PI3K-92D PI3K-92E/Dp110 PI3K-Dp110 PI3K-I PI3K-dp110 PI3K-p60 PI3K-reg PI3K21B PI3K92E PI3k PI4P5K PIP4K PIP5-kinase PIP5K PIP5K 102E PIP5K 59B PIP5K59B PI[[3]]K PP2-AB PP2A PP2A B' PP2A-B PP2A-B' PP2A[B'-1] PP2A[B'-2] PP2a PVF PVF1 PVFs PVR Pi3K Pi3K21B Pi3K92D Pi3K92E Pi3K92E p110 Pi3Kp110 Pi3Kp60 Pi3k Pi3k21B Pi3k92e PiK92E Pp2A-28D Pp2A-29B PvR Pvf Pvf-1 Pvf1 Pvr Src1 Src64B Stumps Tk1 Tk2 VEGF VEGF2-B VEGFR VEGFR-A VGR1 Vav Vegf Vegf17E Vegf17e-a Vegf17e-b Vegfr Vegfr-b Vegfr-c Vgr1 WDB Wdb Widerborst Wrd anon-92Ed anon-EST:CL47 anon-WO0118547.420 anon-WO0172774.174 anon-WO0172774.175 anon-WO0172774.177 anon-WO0172774.179 anon-estC arr arr-RA bnl btl c-erbB chico cka cue dB56-1 dB56-2 dERR dFGF dP110 dP13K dP60 dPI3K dPI3K[92E] dPIP4K dPIP5K dPIP5K59B dPP2A dPP2A-B56-1 dPP2A-B56-2 ddd deltap60 dof dof/hbr dof/hbr/sms dof1 dos dp110 dp110alpha dp60 dpP110 dpip5k drk droPIK57 eg egon fam gene C hbr heartbroken/dof htl i21 i234 i28 klotho kni knrl l(1)G0146 l(2)05475 l(2)05836 l(2)k08131 l(2)s1883 l(3)06916 l(3)09904 l(3)S031807 l(3)S083710 l(3)neo52 mts p110 p120 p60 p85 pi3k pi3k92E pi3k92e pp2A-B' pvf1 pvr rea sktl sms spry stai stumps stumps/dof top type-1 PI3K vegf1 vgr1 vn wbd wdb wrd	Drosophila melanogaster (fruit fly)
Transcriptional activtion by AP-1 transcription factor	Connector of kinase to AP-1, isoform A Stress-activated protein kinase JNK Transcription factor Jra Transcription factor kayak, isoforms A/B/F	P18289 P21525 P92208 Q9VLT9	5836 CKA Cka Dcka Dmel\CG7392 Fra JNK Jra WD-40-family-member anon-WO0172774.174 anon-WO0172774.175 anon-WO0172774.177 anon-WO0172774.179 bsk cka jun kay l(2)05836 l(2)s1883	Drosophila melanogaster (fruit fly)
Formation of the nuclear AP-1 transcription factor 'scaffolding complex'	Connector of kinase to AP-1, isoform A Stress-activated protein kinase JNK Transcription factor Jra Transcription factor kayak, isoforms A/B/F	P18289 P21525 P92208 Q9VLT9	5836 CKA Cka Dcka Dmel\CG7392 Fra JNK Jra WD-40-family-member anon-WO0172774.174 anon-WO0172774.175 anon-WO0172774.177 anon-WO0172774.179 bsk cka jun kay l(2)05836 l(2)s1883	Drosophila melanogaster (fruit fly)
Serotonin Neurotransmitter Release Cycle	Complexin GH10249p Liprin-alpha, isoform E Portabella Protein ROP RIM-binding protein, isoform F Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synapsin Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Unc-13, isoform E	A0A0B4JDC9 A0A0B4K6M2 H9XVP2 M9PCD4 P18489 P21521 P25228 P36975 Q07327 Q24546 Q24547 Q8IH57 Q8IPM8 Q9VCJ5 Q9VH76	CG14867 CG31302 CG5143 CG5152 CG6139 CG7301 CG7305 CG7321 DLiprin DLiprin-alpha DRBP DRIM DUNC-13 DVMAT DVMAT-A DVMAT-B Dliprin-alpha DmRIM Dmel\CG10251 Dmel\CG11199 Dmel\CG2999 Dmel\CG33528 Dmel\CG33547 Dmel\CG43073 Dmel\CG9474 Dunc-13 Dunc13 LIP LIP.1 LIP1 LPR Liprin Liprin-alpha Munc-13 Munc-13/UNC-13 RBP RIM Rab3 Rbp Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syn Syn-1 Syn-2 Syt1 Syx1A UNC-10/RIM UNC-13 UNC-13-B UNC13A UNC13B Unc-13 Unc13 Unc13A Unc13B VMAT Vmat Vmt cpx cs1 dUNC-13 dUnc-13 dVMAT dm-Rim drbp drunc13 dunc-13 l(2)SH0459 l(2)SH2 0459 l(4)ry16 lip-alpha liprin liprin-alpha lpr oos prt rbp rim rim-1 rim-bp syt syx-1A unc unc-13 vmat	Drosophila melanogaster (fruit fly)
Dopamine Neurotransmitter Release Cycle	Complexin GH10249p Liprin-alpha, isoform E Peripheral plasma membrane protein CASK Portabella Protein ROP Protein lin-7 homolog RIM-binding protein, isoform F Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synapsin Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Unc-13, isoform E X11Lbeta, isoform A	A0A0B4JDC9 A0A0B4K6M2 H9XVP2 M9PCD4 P18489 P21521 P25228 P36975 Q07327 Q24210 Q24546 Q24547 Q8IH57 Q8IMT8 Q8IPM8 Q9VCJ5 Q9VH76 Q9W2S5	CASK CG14867 CG1852 CG1861 CG31302 CG5143 CG5152 CG6139 CG7301 CG7305 CG7321 Caki D-veli DLin-7 DLin7 DLiprin DLiprin-alpha DRBP DRIM DUNC-13 DVMAT DVMAT-A DVMAT-B Dliprin-alpha DmRIM Dmel\CG10251 Dmel\CG11199 Dmel\CG2999 Dmel\CG32677 Dmel\CG33528 Dmel\CG33547 Dmel\CG43073 Dmel\CG7662 Dmel\CG9474 Dmint2 Dunc-13 Dunc13 Dveli Flin-7 LIP LIP.1 LIP1 LPR Lin-7 Lin7 Liprin Liprin-alpha Munc-13 Munc-13/UNC-13 RBP RIM Rab3 Rbp Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syn Syn-1 Syn-2 Syt1 Syx1A UNC-10/RIM UNC-13 UNC-13-B UNC13A UNC13B Unc-13 Unc13 Unc13A Unc13B VMAT Veli Vmat Vmt X11B X11LB X11Lbeta X11lbeta cmg cpx cs1 d-Veli dLin-7 dLin7 dUNC-13 dUnc-13 dVMAT dVeli dm-Rim drbp drunc13 dunc-13 l(2)SH0459 l(2)SH2 0459 l(4)ry16 lin-7 lin7 lip-alpha liprin liprin-alpha lpr oos prt rbp rim rim-1 rim-bp syt syx-1A unc unc-13 veli vmat x11Lbeta	Drosophila melanogaster (fruit fly)

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