GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Degradation of the extracellular matrix	72 kDa type IV collagenase ADAM metallopeptidase with thrombospondin type 1 motif 5 Basigin Cathepsin V Decorin Disintegrin and metalloproteinase domain-containing protein 10 Matrix metallopeptidase 10 interstitial collagenase	A0A1L1RX77 E1C9D9 E1C9E0 F1NYJ1 F1P3S7 P17790 Q5F3N4 Q90611	ADAMTS5 BSG CTSV DCN MMP1 MMP10 MMP2 RCJMB04_11h1	Gallus gallus (chicken)
TLR5 cascade	Flagellin Phase 2 flagellin Toll-like receptor 5	P06179 P52616 Q5GR02	H2 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
Ion influx/efflux at host-pathogen interface	Natural resistance-associated macrophage protein 1 PDZ domain-containing protein 11	P51027 Q5ZIK2	NRAMP1 PDZD11 PDZK11 SLC11A1	Gallus gallus (chicken)
Regulation of FZD by ubiquitination	Frizzled-4 Leucine rich repeat containing G protein-coupled receptor 4 Leucine rich repeat containing G protein-coupled receptor 5 Polyubiquitin-B Protein Wnt-3a R-spondin 1 R-spondin 2 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PB24 E1BVU3 E1C2F8 I0IVW2 P0CG62 P79781 Q2LMP1 Q9IA05	FZ4 FZD4 LGR4 LGR5 RPS27A RSPO1 RSPO2 UBA80 UBB WNT3A	Gallus gallus (chicken)
CS/DS degradation	Alpha-L-iduronidase Beta-hexosaminidase Decorin	A0A1L1RX77 F1NTQ2 Q5F366	DCN HEXB RCJMB04_31l23	Gallus gallus (chicken)	G27025MB
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Hematopoietic prostaglandin D synthase Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2	A0A1D5PM03 E2IPN6 O73888 P27607	CEF-147 GSTS HPGDS PGDS PTGDS2 PTGES PTGS1 PTGS2	Gallus gallus (chicken)
Iron uptake and transport	Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase Ferritin heavy chain Iron-responsive element-binding protein 2 Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Proton-coupled folate transporter S-phase kinase-associated protein 1 Solute carrier family 40 member Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P2L3 A0A1D5P546 A0A1D5PBJ1 A0A1D5PQ17 A0A1D5PQV0 F1NHL2 F1NJ67 P08267 P0CG62 P79781 Q5F3K3 Q5ZKF5	ACO1 CAND1 CUL1 CYBRD1 FTH IREB2 PCFT RPS27A SKP1 SKP1A SLC40A1 SLC46A1 UBA80 UBB	Gallus gallus (chicken)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-9 Neuronal acetylcholine receptor subunit beta-4	F1P4U2 P09481 P09482 Q9PTS8	CHRNA3 CHRNA4 CHRNA9 CHRNB4	Gallus gallus (chicken)
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin, cytoplasmic 2 Albumin Alpha-1-acid glycoprotein Alpha-actinin-1 Alpha-actinin-2 Amyloid beta like protein 2 Annexin A5 Apolipoprotein A-I C-type lectin domain family 3 member B CYFIP related Rac1 interactor B Coagulation factor XIII A chain Fibronectin GTP binding protein 2 Hsp90 co-chaperone Cdc37-like 1 Insulin-like growth factor I Insulin-like growth factor II Integrin beta Intracellular hyaluronan-binding protein 4 LHFPL tetraspan subfamily member 2 MAGE protein Metalloproteinase inhibitor 3 Obg-like ATPase 1 Plasminogen Platelet-derived growth factor subunit A Protein FAM3C Retinoic acid receptor responder protein 2 Saccharopine dehydrogenase-like oxidoreductase Sulfhydryl oxidase 1 Tetraspanin Torsin family 4 member A Transforming growth factor beta Transforming growth factor beta Vascular endothelial growth factor D Vesicle transport through interaction with t-SNAREs 1B Vinculin	A0A0K0PUH6 A0A165EAY6 A0A1D5NW68 A0A1D5PSS5 A0A1D5PZ00 E1BUX5 E1BVB5 E1BWA9 E1BWG1 F1NAG8 F1NH83 F1NLT2 F1NNP2 F1NWX6 F1P0A7 H9CX01 P05094 P08250 P11722 P12003 P17153 P18254 P20111 P26652 P33717 Q001T8 Q5ZM25 Q5ZMK3 Q5ZMQ2 Q8JGM4 Q8JIG5 Q90WK2 Q92071 Q9DDD4 Q9I9R0 Q9IBC9	ABCC4 ACTG1 ACTN1 ACTN2 ALB ANX5 ANXA5 APLP2 APOA1 CD9 CDC37L1 CLEC3B F13A1 FAM3C FAM49B FN1 GTPBP2 HABP4 IGF1 IGF2 IMP-3 ITGB3 LHFPL2 OGCHI OLA1 ORM1 PDGF-A (L) PDGFA PLG QSCN6 QSOX QSOX1 RARRES2 RCJMB04_1m12 SOX TGFB1 TGFB2 TIMP3 TOR4A VCL VEGFD VINC1 VTI1B mage ogchi	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)
Insulin receptor recycling	ATPase H+ transporting V0 subunit b Cathepsin D H(+)-transporting two-sector ATPase Insulin Tyrosine-protein kinase receptor V-type proton ATPase proteolipid subunit V-type proton ATPase subunit G V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 2 V-type proton ATPase subunit VATE1 ATPase Vacuolar proton pump subunit B protein-tyrosine-phosphatase	A0A1D5P5R9 A0A1D5P6L6 A0A1D5P6T3 A0A1D5PCU0 A0A1D5PP57 A0A1I7Q402 A0A1L1RUN2 F1NBW2 P67970 Q05744 Q5ZHL0 Q5ZJ19 Q5ZJC4 Q5ZKJ9	ATP6V0A1 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D2 ATP6V0E1 ATP6V1A ATP6V1B2 ATP6V1G3 CTSD INS INSR PTPN1 RCJMB04_10e23	Gallus gallus (chicken)
Heme signaling	Apolipoprotein A-I Beta-H globin Exportin 1 Hemoglobin subunit alpha-A Hemoglobin subunit beta Hemoglobin subunit rho Progesterone receptor membrane component 2 Proton-coupled folate transporter Toll-like receptor 4 Transcription factor MafK	A0A1D5P8H7 C4PCF3 F1NJ67 P01994 P02112 P02127 P08250 Q5ZLX0 Q90596 Q90864	APOA1 HBAA HBB HBE1 MAFK PCFT PGRMC2 SLC46A1 TLR4 XPO1	Gallus gallus (chicken)
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin beta B chain TGF-beta family profile domain-containing protein Thyrotropin subunit beta	A0A3Q2TUG3 F1NJD3 O57340 Q8QGF8 R4GIS0	CGA FSH beta FSHB FSHb INHBB INHBE TSHB	Gallus gallus (chicken)
Signaling by SCF-KIT	GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5P405 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BQF3 E1C2C5 E1C7Z1 F1NZY8 P00523 P08642 P09324 Q08156 Q09108 Q5F352 Q5ZJK3 Q6DV79 Q90687 R4GHL2	FER FYN GRAP2 GRB10 GRB2 HRAS HRAS1 KIT KITLG KRAS NRAS PIK3R1 PIK3R2 PRKCA PTPN11 RCJMB04_17i9 SCF SOS1 SRC STAT3 TEC YES YES1	Gallus gallus (chicken)
Proton-coupled monocarboxylate transport	Basigin Monocarboxylate transporter 1 Monocarboxylate transporter 2	F1NVU4 P17790 Q5ZLZ6	BSG RCJMB04_4e8 SLC16A7	Gallus gallus (chicken)
Norepinephrine Neurotransmitter Release Cycle	Complexin-1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-binding protein 1 Unc-13 homolog B	A0A1D5PHU2 E1C8G7 F1NY18 P47191 P60878	CPLX1 SNAP SNAP25 STXBP1 SYT1 UNC13B	Gallus gallus (chicken)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor X	P25155	F10 FX	Gallus gallus (chicken)
Assembly of the pre-replicative complex	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Anaphase-promoting complex subunit CDC26 Cell division cycle protein 27 homolog DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 Fizzy/cell division cycle 20 related 1 Polyubiquitin-B Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Ubiquitin B Ubiquitin-conjugating enzyme E2 C Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PJW4 A0A3Q2UD09 E1BX02 E1C2U4 E1C6N0 F1NC02 F1NEQ6 F1NFJ0 F1NPQ0 F1NR71 H9L1Y1 P0CG62 P79781 P84169 Q5F3J5 Q5ZIT7 Q5ZJL3 Q5ZJX9 Q5ZK91 Q5ZKL0 Q5ZKR8 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 R4GJY8 R4GLB3	CDC26 FZR1 MCM3 MCM4 MCM5 PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 PSME3 PSMF1 RCJMB04_12e16 RCJMB04_14i9 RCJMB04_23k2 RCJMB04_9i8 RPS27A UBA80 UBB UBE2U cpsmb7	Gallus gallus (chicken)
Phospholipase C-mediated cascade: FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1	Gallus gallus (chicken)
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Leucine rich repeat containing 8 VRAC subunit C Leucine rich repeat containing 8 VRAC subunit D Lysosomal amino acid transporter 1 homolog NIPA like domain containing 3 Non imprinted in Prader-Willi/Angelman syndrome 2	A0A3Q2TZ76 E1BQK4 E1BR96 E1BYZ5 E1BZK2 E1C957 F1NBX2 Q5ZJX0	ANKH LOC107056693 LRRC8A LRRC8C LRRC8D NIPA2 NIPAL3 PQLC2 SLC66A1	Gallus gallus (chicken)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha Rhodopsin	F1P3Y2 Q90980	RHO	Gallus gallus (chicken)
Gluconeogenesis	Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate mutase 1 Solute carrier family 37 member 4 Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 F1NKP4 F1NTA5 F1NTH9 P00356 P00940 P07341 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 G6PC2 GAPD GAPDH GPI PCK1 PGAM1 SLC37A4 TPI1	Gallus gallus (chicken)	G58161NS
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor X Osteocalcin furin	A0A1D5PRL0 P25155 Q91000	BGLAP F10 FURIN FX	Gallus gallus (chicken)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor receptor 1 Fibroblast growth factor	P21804 R4GIR0	CEK1 FGF23 FGFR1	Gallus gallus (chicken)
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)

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