GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
p75NTR recruits signalling complexes	Myeloid differentiation primary response protein MyD88 Polyubiquitin-B Protein kinase C Sequestosome 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 16 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PLN4 A5HNF6 E1BWA3 E1C626 P0CG62 P18519 P79781	MYD88 NGFR PRKCI RPS27A SQSTM1 TNFRSF16 TRAF6 UBA80 UBB	Gallus gallus (chicken)
Lectin-mediated initiation of complement cascade	MAp19 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein	Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	MASP2 MBL	Gallus gallus (chicken)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase	F1P0Z9	MAN1C1	Gallus gallus (chicken)	G70323CJ
Lactose synthesis	Lysozyme C	P00698	LYZ	Gallus gallus (chicken)	G58161NS G74621DY
MyD88:TIRAP-dependent cascade initiated on plasma membrane	Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 4 Toll/interleukin-1 receptor domain-containing adapter protein	A0A8V0XHS1 A5H0S2 A5HNF6 Q4U127 Q5F382 Q5WA51 Q5ZJM6 Q7ZTG5 Q9DD78	LY96 MYD88 RCJMB04_17b10 RCJMB04_29d24 TIRAP TLR1 TLR1Lb TLR2-1 TLR4	Gallus gallus (chicken)
P2Y receptors	Lysophosphatidic acid receptor 4 P2Y purinoceptor 1 P2Y purinoceptor 3	E1BWJ9 P34996 Q98907	LPAR4 P2RY1 P2RY3	Gallus gallus (chicken)
Receptor-type tyrosine-protein phosphatases	NT-3 growth factor receptor SLIT and NTRK like family member 1 SLIT and NTRK like family member 2	F1NEZ4 F1NZH0 Q91044	LOC121106448 NTRK3 SLITRK1 TRKC	Gallus gallus (chicken)
Voltage gated Potassium channels	Potassium voltage-gated channel modifier subfamily F member 1 Potassium voltage-gated channel modifier subfamily G member 1 Potassium voltage-gated channel modifier subfamily G member 4 Potassium voltage-gated channel modifier subfamily S member 2 Potassium voltage-gated channel modifier subfamily S member 3 Potassium voltage-gated channel subfamily A member 10 Potassium voltage-gated channel subfamily A member 2 Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 4 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily B member 2 Potassium voltage-gated channel subfamily C member 4 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily D member 3 Potassium voltage-gated channel subfamily G member 2 Potassium voltage-gated channel subfamily H member 1 Potassium voltage-gated channel subfamily H member 8 Potassium voltage-gated channel subfamily Q member 5 Potassium voltage-gated channel subfamily V member 1 Voltage-gated potassium channel subunit beta-1	A0A1D5P1M1 A0A1D5P7T5 A0A1D5PA94 A0A1D5PCF8 A0A1D5PI60 A0A1D5PI98 E1BQU8 E1BS72 E1BWF1 E1BYX3 E1C3M8 E1C3U8 F1NK95 F1NRL8 F1P320 O73606 Q7T199 Q7T1A0 Q9PWR1 Q9YGX8	KCNA10 KCNA2 KCNA3 KCNA4 KCNAB1 KCNB1 KCNB2 KCNC4 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG4 KCNH1 KCNH8 KCNQ5 KCNS2 KCNS3 KCNV1 KVB1.1	Gallus gallus (chicken)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma	E1C5K7 P01109 Q5F3R2	JARID1B KDM5B MYC TFAP2C	Gallus gallus (chicken)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A0A1D5P6T3 P67970	INS INSR	Gallus gallus (chicken)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Insulin-like growth factor I Insulin-like growth factor II	P18254 P33717	IGF1 IGF2	Gallus gallus (chicken)
IRS-related events triggered by IGF1R	Insulin-like growth factor I Insulin-like growth factor II	P18254 P33717	IGF1 IGF2	Gallus gallus (chicken)
Interleukin-20 family signaling	Interferon lambda receptor 1 Interferon lambda-3 Interleukin 22 receptor subunit alpha 1 Interleukin 22 Interleukin family protein Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A1D5PNV3 B4ER10 E1BRV0 E1C1U2 E1C5G0 F1NMJ9 K9JA28 Q5ZJK3 Q6DV79 Q90687	IFNL IFNL3 IFNLR1 IL22 IL22RA1 IL28 IL28B IL28RA JAK1 LOC107055197 PTPN11 RCJMB04_17i9 STAT3 STAT4	Gallus gallus (chicken)
Regulation of IFNG signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase	A0A1D5PS87 B6RCQ2 F1NMJ9 P49708 Q5ZJK3 Q8QGH2 R4GJH9	IFNG IFNGR2 JAK1 RCJMB04_17i9 SOCS1 SOCS3 SUMO1	Gallus gallus (chicken)
IFNG signaling activates MAPKs	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase	A0A1D5PS87 F1NMJ9 P05625 P49708	IFNG IFNGR2 JAK1 MIL RAF1	Gallus gallus (chicken)
Regulation of IFNA/IFNB signaling	Interferon alpha Interferon type A1/A2 Interferon type B Interferon Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 protein-tyrosine-phosphatase	A0A1I7Q402 B0FLN7 F1NMJ9 P42165 Q5ZJK3 Q90687 Q90873 Q9PWI5	IFN-gamma IFN2 IFNA IFNA1 IFNA2 IFNA3 IFNB JAK1 LOC100857947 LOC100858506 LOC100859414 LOC768614 PTPN1 PTPN11 RCJMB04_17i9	Gallus gallus (chicken)
Hyaluronan biosynthesis and export	Hyaluronan synthase 3	O57425	HAS3	Gallus gallus (chicken)	G35674CY
Chromatin modifying enzymes	Histone H3.2 Protein-arginine deiminase protein-arginine deiminase	E1C0W6 P84229 S6BNL5	H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII PADI1 PADI2 cPAD1 cPAD2	Gallus gallus (chicken)
HATs acetylate histones	E3 ubiquitin-protein ligase MSL2 Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone acetyltransferase type B catalytic subunit MSL complex subunit 3 Nuclear receptor coactivator Paired box 3	A0A1D5NVS8 A0A1D5PS75 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1P5A3 P02263 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 Q5F393 Q8QGS3 Q9PSW9	H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HAT1 HIST1H2B5L LOC426037 MSL2 MSL3 NCOA1 PAX3 Pax3	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)
RNA Polymerase I Promoter Opening	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037	Gallus gallus (chicken)
Assembly of the ORC complex at the origin of replication	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Importin subunit alpha Karyopherin subunit beta 1	A0A1D5P1W7 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 F7B5S0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KPNA6 KPNB1 LOC100859381 LOC426037	Gallus gallus (chicken)
TLR5 cascade	Flagellin Phase 2 flagellin Toll-like receptor 5	P06179 P52616 Q5GR02	H2 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
MyD88 cascade initiated on plasma membrane	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 Phase 2 flagellin Toll-like receptor 2 Toll-like receptor 5	A5HNF6 P06179 P52616 Q2XQ10 Q5F382 Q5GR02 Q5ZJM6	H2 MYD88 RCJMB04_17b10 RCJMB04_29d24 TLR15 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
NFkB and MAPK activation mediated by TRAF6	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 PPM-type phosphatase domain-containing protein Phase 2 flagellin Polyubiquitin-B TNF receptor-associated factor Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 5 Toll/interleukin-1 receptor domain-containing adapter protein Ubiquitin-ribosomal protein eL40 fusion protein (Fragment) Ubiquitin-ribosomal protein eS31 fusion protein	A0A8V0XHS1 A5H0S2 A5HNF6 E1C626 P06179 P0CG62 P52616 P62985 P79781 Q2XQ10 Q4U127 Q5F382 Q5GR02 Q5WA51 Q5ZJM6 Q5ZJW3 Q7ZTG5 Q9DD78	H2 LY96 MYD88 RCJMB04_15c17 RCJMB04_17b10 RCJMB04_29d24 RPS27A TIRAP TLR1 TLR15 TLR1Lb TLR2-1 TLR4 TLR5 TRAF6 UBA52 UBA80 UBB UBCEP2 flaF fliC fljB hag	Gallus gallus (chicken)

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