GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
WNT5A-dependent internalization of FZD4	Frizzled-4 Protein Wnt	Q9IA05 Q9YGX6	FZ4 FZD4 WNT5A	Gallus gallus (chicken)
Ficolins bind to repetitive carbohydrate structures on the target cell surface				Gallus gallus (chicken)	G49108TO G57321FI
Synthesis of PC	Abhydrolase domain containing 3, phospholipase Choline O-acetyltransferase Choline transporter-like protein Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Sodium-dependent lysophosphatidylcholine symporter 1 ethanolamine kinase	A0A1D5P2G3 A0A3Q3AVJ7 F1NCD6 F1NT05 F1NTP8 F1P393 Q5ZHQ5	ABHD3 CEPT1 CHAT CHKA CHPT1 MFSD2A NLS1 SLC44A5	Gallus gallus (chicken)
NFG and proNGF binds to p75NTR	Tumor necrosis factor receptor superfamily member 16	P18519	NGFR TNFRSF16	Gallus gallus (chicken)
Glucose transport	Hexokinase-1 Hexokinase-2 Phosphotransferase (Fragment) Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3	P28568 P46896 Q8AYP7 Q8AYP8 Q8JHA6 Q90592	GLUT1 GLUT2 GLUT3 HK1 HK2 SLC2A1 SLC2A2 SLC2A3	Gallus gallus (chicken)	G58161NS
Peptide ligand-binding receptors	Apelin receptor Apelin B1 bradykinin receptor Bombesin receptor subtype-3 Cholecystokinin receptor type A Coagulation factor II thrombin receptor like 2 Endothelin-1 receptor Endothelin-2 Endothelin-converting enzyme 1 F2R like trypsin receptor 1 G protein-coupled receptor 37 like 1 G-protein coupled estrogen receptor 1 Galanin peptides Galanin receptor Gastrin-releasing peptide Kappa-type opioid receptor Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Motilin receptor Mu-type opioid receptor Neuromedin B Neuromedin U receptor 2 Neuromedin U receptor type 1 Neuromedin U Neuromedin-B receptor Neuromedin-S Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor 4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptides B and W receptor 1 Neurotensin receptor 1 Nociceptin receptor PMCH Pancreatic polypeptide Peptide YY Prepronociceptin isoform X1 variant X1 Preprourotensin II Pro-neuropeptide Y Pro-thyrotropin-releasing hormone Proenkephalin Prokineticin 2 Somatostatin II Somatostatin receptor 1 Somatostatin receptor 4 Somatostatin receptor 5 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Urotensin-2 receptor XK-related protein	A0A0S3UPI6 A0A172PWX7 A0A1D5P3F4 A0A1D5P8Y9 A0A1D5PAZ6 A0A1D5PKZ0 A0A1L7HA09 A0A2I6J485 A0A3Q2U9J5 A0A3S5ZP53 A0MAR6 A0ZPS0 A9UGZ3 B2KSC0 B2ZE94 C3V8R3 E1BRK8 E1BRP1 E1BWP2 E1BX29 E1BYD3 E1BYR3 E1C0V9 E1C327 E1C482 E1C652 E1C968 E7FKE5 F1NEH2 F1NJ18 F1NP50 F1NQE8 F1NTV9 F1NW54 F1NWC2 F1NWY5 F1P2V3 F6RCI2 O73739 P01295 P28673 P33094 P68248 P79785 Q38Q38 Q4ZJF2 Q58G84 Q5F4D0 Q6Q2J6 Q6ZXC3 Q802E6 Q802G0 Q8QFM1 Q8QGM3 Q9DDN6 Q9DGN6 R4GF58	AGTR1 APLN APLNR APLNR1 BDKRB1 BRS3.5 CCK1R CCKAR ECE-1 EDN2 EDNRA F2RL1 F2RL2 GAL GALR GPER1 GPR37L1 GRP MC1R MC4R MC5R MLNR Mc1r NMB NMBR NMS NMU NMUR1 NMUR2 NPBWR1 NPSR1 NPW NPY NPY1R NPY2R NPY4R NPY5R NTSR1 OPRK1 OPRL1 OPRM1 PENK PMCH PNOC PPY PROK2 PYY SS1R SS2 SS2R SS3R SST SSTR1 SSTR2 SSTR4 SSTR5 TRH TRHR UTS2 UTS2R XK	Gallus gallus (chicken)
Biosynthesis of DHA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
G alpha (s) signalling events	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 5-hydroxytryptamine receptor 4 ADCYAP receptor type I Adenosine receptor A2b Adenylate cyclase activating polypeptide 1 Adrenoceptor beta 3 Amyloid protein Beta-2 adrenergic receptor Calcitonin gene-related peptide type 1 receptor Calcitonin Corticotropin releasing hormone Corticotropin-releasing factor receptor 1 Follitropin subunit beta G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled pituitary GHRH receptor G protein-coupled receptor 27 G protein-coupled receptor kinase G-protein coupled receptor 39 Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Glycoprotein hormones alpha chain Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(s) subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H2 receptor Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Neuropeptide S receptor Neuropeptide S Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Phosphodiesterase Phosphodiesterase Pro-glucagon Prostaglandin D2 receptor Prostaglandin E receptor 2 Prostaglandin E2 receptor EP4 subtype Receptor activity modifying protein 2 Receptor activity-modifying protein 3 Somatoliberin Thyrotropin subunit beta VIP peptides VPAC2 receptor	A0A1D5P7A9 A0A1D5P7Q2 A0A1D5P7Z5 A0A1D5P8Y9 A0A1D5PKZ0 A0A1D5PLZ8 A0A1D5PP20 A0A3Q2TWD9 A0A3Q2TZX9 A0A3Q2U4U2 A0A3Q2U9J5 A0A3Q2UHX2 A1XWZ9 A2TH16 A7UH64 B0FYW9 B4ZY91 B9VGZ4 C4P7J2 C5HV42 C7S302 E1BQG4 E1BW98 E1C1U6 E1C4B7 E1C795 F1NDL3 F1NJD3 F1NJL4 F1NLV4 F1NQE8 F1NS14 F1NUQ9 G9BWP6 O13076 O57340 P15743 P17251 P48143 P68259 Q1KNA7 Q309X7 Q56IA1 Q58FG9 Q5ZJ03 Q703P0 Q802G0 Q8QGF8 Q90743 R4GFT9 R4GKD1	ADCYAP1 ADCYAP1R1 ADORA2B ADRB2 ADRB3 CALCA CALCRL CGA CRH CRHR1 EP4 FSH beta FSHB FSHb GCG GHRH GHRHR GLP-1R GLP2R GNAS GNASXL GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 GPR27 GPR39 GRK5 HRH2 HTR4 HTR7 IAPP LOC107051813 MC1R MC4R MC5R Mc1r NPSR1 PACAP PDE4D PDE7B PTGER2 PTGER4 PTH PTH1R PTH2R PTHLH RAMP2 RAMP3 TSHB VIP VPAC2	Gallus gallus (chicken)
Neurotransmitter receptors and postsynaptic signal transmission	Glycine receptor beta	F1P037	GLRB	Gallus gallus (chicken)
Digestion	Guanylate cyclase activator 2B Guanylate cyclase	E1BZE2 R4GIC2	GUCA2B GUCY2C	Gallus gallus (chicken)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Betacellulin Caveolin Epigen Epiregulin Focal adhesion kinase 1 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Matrix metallopeptidase 10 Palmitoyltransferase Palmitoyltransferase Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1	A0A1D5NVK1 A0A1D5NYP8 A0A1D5P1F1 A0A1D5P7Z5 A0A1D5PKH0 A0A1D5PLZ8 A0A3Q2U4X3 A0A3Q3ACS4 A0M8T8 E1BW98 E1BXS2 E1C1U6 E1C2C5 E1C795 E1C9E0 F1NJR9 F1NLV4 F1P3R0 P00523 P50147 Q00944 Q5EG71 Q5F3P6 Q5ZJ03 Q645M5 Q64EU6 Q90611 Q90847 Q9W7C5 R4GFT9 R4GKD1	AKT1 AREG BTC CAV1 EGFR EPGN EREG FAK FAK1 GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 Galphai3 HBEGF HEGFL MMP10 MMP2 PIK3R1 PIK3R2 PTK2 SHC1 SPHK1 SRC ZDHHC21 ZDHHC7	Gallus gallus (chicken)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A1D5PEZ2 A3R0S3 E1C021 P25429 Q91987	BDNF FRS2 GRB2 NTRK2 SOS1 TRKB	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Catenin beta-1 Frizzled class receptor 3 Frizzled-4 G protein subunit alpha transducin 2 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Lymphoid enhancer binding factor 1 Phosphodiesterase Protein Wnt-11 Protein Wnt Protein phospatase 3 regulatory subunit B alpha isoform type 1 Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma calcium/calmodulin-dependent protein kinase small monomeric GTPase	A0A1D5NTJ0 A0A1D5NYE8 A0A1D5NZL7 A0A1D5P7Z5 A0A1D5PLZ8 A0A1D5PT95 A0A1D5PZ45 A0A3Q2UEZ9 A0A3Q3B1W2 E1BW98 E1C1U6 E1C795 F1NA42 F1NGS8 F1NLV4 P49339 Q5ZJ03 Q6VN51 Q802E4 Q9IA05 Q9YGX6 R4GFT9 R4GKD1	CAMK2A CTNNB1 FZ4 FZD3 FZD4 GNAO1 GNAT2 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 KRAS LEF1 OXLD1 PDE6B PDE6b PLCB1 RCJMB04_23k16 WNT-11 WNT11 WNT5A	Gallus gallus (chicken)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Autocrine motility factor receptor Polyubiquitin-B Transitional endoplasmic reticulum ATPase Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 F1NBB7 P0CG62 P79781 Q5ZMU9	AMFR RPS27A UBA80 UBB VCP vcp	Gallus gallus (chicken)	G03934XO G25577BM G28233ME G51034LA G86419OL
Highly calcium permeable nicotinic acetylcholine receptors	Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-4	F1P4U2 P09481 P09482	CHRNA3 CHRNA4 CHRNB4	Gallus gallus (chicken)
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog Endophilin-A1 Epigen Epiregulin Growth factor receptor-bound protein 2 Polyubiquitin-B Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain-containing protein Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PKH0 A0A3Q2TZR1 A3R0S3 A4LA71 F1NB17 F1NJR9 P0CG62 P79781 Q5EG71 Q5ZMQ7 Q645M5 Q64EU6 Q8AXV1 Q90694 Q9W7C5	AREG ARHGEF7 BTC CDC42 EGFR EPGN EREG GRB2 HBEGF HEGFL RCJMB04_1g20 RPS27A SH3GL2 SH3GL3 SH3P4 SPRY1 UBA80 UBB	Gallus gallus (chicken)
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Opsins	Opsin 3 Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin	E1C1F4 F1NEL9 F1NEY2 F1P193 F1P3Y2	OPN3 OPN5 RGR RHO RRH cOpn3m	Gallus gallus (chicken)
Regulation of insulin secretion	ATP-sensitive inward rectifier potassium channel 11 Rap guanine nucleotide exchange factor 4 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 cAMP-dependent protein kinase	A0A1D5PMC0 A0A3Q3AHR0 E1BZF6 F1NBC9 O73700 R4GIN8	CACNA1D CACNB2 KCNJ11 LOC107050029 PRKACB RAPGEF4	Gallus gallus (chicken)	G58161NS
Metabolism of Angiotensinogen to Angiotensins	Cathepsin D Neprilysin	Q05744 Q67BJ2	CTSD MME	Gallus gallus (chicken)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase Protein-tyrosine sulfotransferase protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	A0A3Q2UD60 E1BRW8 F1NGS3 Q5ZMU7 R4GG02	FN3K FN3KRP ICMT TPST1 TPST2	Gallus gallus (chicken)
GAB1 signalosome	Amphiregulin Betacellulin Epigen Epiregulin Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase Tyrosine-protein phosphatase non-receptor type 11	A0A1D5PKH0 A0A3Q3ACS4 A3R0S3 F1NJR9 P00523 Q5EG71 Q645M5 Q64EU6 Q90687 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL PIK3R1 PTPN11 SRC	Gallus gallus (chicken)
Nicotinamide salvaging	NAD-capped RNA hydrolase NUDT12 Nicotinamide phosphoribosyltransferase Prostaglandin G/H synthase 2 Sodium-coupled monocarboxylate transporter 1	E1C2E5 F1P5L0 P27607 Q58I02	CEF-147 NAMPTP1 NUDT12 PBEF1 PTGS2 SLC5A8	Gallus gallus (chicken)
Intrinsic Pathway of Fibrin Clot Formation	Coagulation factor X Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Prolylcarboxypeptidase Serpin family D member 1 Serpin family E member 2 Tsukushi	A0A1D5PLZ2 A0A1D5PVG8 A0A3Q3AXX7 E1BWU2 F1P1G3 P25155 Q65Z91	F10 FX GP1BB GP9 LRRC54 PRCP SERPIND1 SERPINE2 TSK TSKU	Gallus gallus (chicken)

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