GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Signaling by SCF-KIT	GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5P405 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BQF3 E1C2C5 E1C7Z1 F1NZY8 P00523 P08642 P09324 Q08156 Q09108 Q5F352 Q5ZJK3 Q6DV79 Q90687 R4GHL2	FER FYN GRAP2 GRB10 GRB2 HRAS HRAS1 KIT KITLG KRAS NRAS PIK3R1 PIK3R2 PRKCA PTPN11 RCJMB04_17i9 SCF SOS1 SRC STAT3 TEC YES YES1	Gallus gallus (chicken)
GRB2:SOS provides linkage to MAPK signaling for Integrins	Fibronectin Focal adhesion kinase 1 Growth factor receptor-bound protein 2 Integrin beta Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1b SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5PEZ2 A3R0S3 F1NSA8 P00523 P11722 Q00944 Q5ZHX1 Q92071	FAK FAK1 FN1 GRB2 ITGB3 PTK2 RAP1A RAP1B SOS1 SRC	Gallus gallus (chicken)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor X	P25155	F10 FX	Gallus gallus (chicken)
Intrinsic Pathway of Fibrin Clot Formation	Coagulation factor X Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Prolylcarboxypeptidase Serpin family D member 1 Serpin family E member 2 Tsukushi	A0A1D5PLZ2 A0A1D5PVG8 A0A3Q3AXX7 E1BWU2 F1P1G3 P25155 Q65Z91	F10 FX GP1BB GP9 LRRC54 PRCP SERPIND1 SERPINE2 TSK TSKU	Gallus gallus (chicken)
Common Pathway of Fibrin Clot Formation	Coagulation factor X Coagulation factor XIII A chain Endothelial protein C receptor Serpin family D member 1 Serpin family E member 2	A0A1D5PLZ2 E1BWG1 E1BWU2 P25155 Q4ADW2	F10 F13A1 FX PROCR SERPIND1 SERPINE2	Gallus gallus (chicken)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Pro-glucagon	A0A1D5P7Z5 A0A1D5PJA5 E1C1U6 F1NLV4 F1P3R0 M9NJI3 P01295 P68259	DPP4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP	Gallus gallus (chicken)	G58161NS
RET signaling	Docking protein 1 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0E4BA89 A0A1D5NYP8 A0A1D5P405 A0A1D5PEZ2 A0A1D5PZ39 A0A3Q3ACS4 A3R0S3 E1C021 E1C2C5 F1NHX1 O13156 P00523 Q5F4A2 Q90687 R4GHL2	DOK1 FRS2 GDNFRA GFRA1 GRB10 GRB2 PDLIM7 PIK3CB PIK3CD PIK3R1 PIK3R2 PRKCA PTPN11 SHC1 SOS1 SRC	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
Effects of PIP2 hydrolysis	Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor Protein kinase C delta type Protein kinase C Transient receptor potential cation channel subfamily C member 7	A0A1D5PLX8 F1NDU2 F1NJH1 F1NYQ1 F1P1X4 F1P3G1	DGKB DGKK ITPR2 PRKCD PRKCH TRPC7	Gallus gallus (chicken)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco	Q5F422	DEK	Gallus gallus (chicken)
CS/DS degradation	Alpha-L-iduronidase Beta-hexosaminidase Decorin	A0A1L1RX77 F1NTQ2 Q5F366	DCN HEXB RCJMB04_31l23	Gallus gallus (chicken)	G27025MB
Reelin signalling pathway	DAB1, reelin adaptor protein SH3 domain-containing protein Tyrosine-protein kinase Very low-density lipoprotein receptor	A0A3Q2U639 P98165 Q5ZMQ7 Q6XBN6	DAB1 Dab1 FYN RCJMB04_1g20 VLDLR VTGR	Gallus gallus (chicken)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	GTP-binding protein Par-6 family cell polarity regulator alpha Polyubiquitin-B Protein kinase C TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 E1BQN6 F1P0U8 H9CX01 O93467 P0CG62 P79781 Q06900 Q90999	ChALK5 PARD6A PRKCZ RHOA RPS27A TGFB1 TGFBR1 TGFBR2 UBA80 UBB cRhoA rhoA	Gallus gallus (chicken)
TGF-beta receptor signaling activates SMADs	Integrin beta Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor 3 Transforming growth factor beta Transforming growth factor beta Zinc finger FYVE domain-containing protein furin peptidylprolyl isomerase	A0A1D5NUH3 E1C6T3 F1NNP2 H9CX01 P84023 Q06900 Q8UWF3 Q90998 Q90999 Q90ZG0 Q91000 Q92071	ChALK5 FKBP12 FURIN ITGB3 LOC769000 MADH2 MADH3 SMAD3 TGFB1 TGFB2 TGFBR1 TGFBR2 TGFBR3 ZFYVE9	Gallus gallus (chicken)
TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Toll-like receptor 4	A0A8V0XHS1 B0BL87 Q7ZTG5	Cd14 LY96 TLR4	Gallus gallus (chicken)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Cytochrome b5 Major prion protein homolog Protein transport protein Sec61 subunit beta	F1NWX7 P00174 P27177	CYB5 CYB5A PRN-P PRNP SEC61B	Gallus gallus (chicken)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin V Ovalbumin	F1NYJ1 P01012	CTSV SERPINB14	Gallus gallus (chicken)
Metabolism of Angiotensinogen to Angiotensins	Cathepsin D Neprilysin	Q05744 Q67BJ2	CTSD MME	Gallus gallus (chicken)
ECM proteoglycans	Decorin Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin subunit alpha 9 Matrilin-3	A0A1D5PQP8 A0A1L1RX77 O42401 P07354 Q92071	CRTL1 DCN HAPLN1 ITGA9 ITGB3 MATN3	Gallus gallus (chicken)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Fibronectin Focal adhesion kinase 1 Integrin beta Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1b small monomeric GTPase	F1NSA8 P00523 P11722 Q00944 Q04929 Q5ZHX1 Q92071	CRK FAK FAK1 FN1 ITGB3 PTK2 RAP1A RAP1B SRC	Gallus gallus (chicken)
The canonical retinoid cycle in rods (twilight vision)	Dehydrogenase/reductase 9 Lecithin retinol acyltransferase Retinaldehyde-binding protein 1 Retinol dehydrogenase 11 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A1I7Q422 E1BTL3 E1C1U1 E1C781 F1P3Y2 F1P4T5 P41263	CRALBP LOC121106449 LRAT RBP4 RDH11 RHO RLBP1 TTR	Gallus gallus (chicken)
Norepinephrine Neurotransmitter Release Cycle	Complexin-1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-binding protein 1 Unc-13 homolog B	A0A1D5PHU2 E1C8G7 F1NY18 P47191 P60878	CPLX1 SNAP SNAP25 STXBP1 SYT1 UNC13B	Gallus gallus (chicken)
Arachidonic acid metabolism	Cytosolic phospholipase A2	P49147	CPLA2 PLA2G4 PLA2G4A	Gallus gallus (chicken)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma P2Y purinoceptor 1 Proto-oncogene tyrosine-protein kinase Src mitogen-activated protein kinase	A0A1D5P7Z5 A0A1D5PIQ5 A0A1D5PLZ8 E1BW98 E1C1U6 E1C795 F1NLV4 P00523 P34996 P49147 Q5F3B5 Q5ZJ03 Q71RI7 R4GFT9 R4GKD1	CPLA2 GNA11 GNAQ GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 MAPK14 P2RY1 PLA2G4 PLA2G4A SRC	Gallus gallus (chicken)
Signaling by PDGF	Collagen type IV alpha 1 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor subunit A Thrombospondin 4 furin	A0A1D5P8P3 A0A3Q2U6E1 E1C209 F1NBP0 F1NWX6 Q90WK2 Q91000 Q9I946	COL4A1 FURIN PDGF-A (L) PDGFA PDGFC PDGFD PLAT PLG SCDGF THBS4	Gallus gallus (chicken)

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