GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **263** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
TNFR2 non-canonical NF-kB pathway	B-cell-activating factor BAFF CD40 ligand TNF receptor superfamily member 1B TNF receptor-associated factor	A0A1D5PTU3 A0A3Q3AAA5 Q8JHJ4 Q9I8D8	BAFF CD40L CD40LG TNFRSF1B TNFSF13B TNFSF5 TRAF3	Gallus gallus (chicken)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell-activating factor BAFF CD40 ligand TNF receptor-associated factor	A0A3Q3AAA5 Q8JHJ4 Q9I8D8	BAFF CD40L CD40LG TNFSF13B TNFSF5 TRAF3	Gallus gallus (chicken)
Myogenesis	BCL2 interacting protein 2 Cadherin-2 Catenin beta-1 Cell division control protein 42 homolog Mitogen-activated protein kinase 12 Myocyte enhancer factor 2D Myogenic factor 6 Myogenic factor Myogenic factor Myogenin mitogen-activated protein kinase	A0A1D5NYE8 A0A1D5NYL4 A0A1D5PIQ5 F1NEC1 F1NHM3 F1NLU9 P10288 P17920 Q01795 Q90694 R4GMI9	BNIP2 CDC42 CDH2 CTNNB1 MAPK12 MAPK14 MEF2D MRF4 MYF5 MYF6 MYOD1 MYOG	Gallus gallus (chicken)
Formation of the beta-catenin:TCF transactivating complex	BCL9 transcription coactivator Catenin beta-1 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Lymphoid enhancer binding factor 1 Parafibromin Pygopus family PHD finger 1 RB binding protein 5, histone lysine methyltransferase complex subunit RuvB-like helicase TLE family member 1, transcriptional corepressor TLE family member 3, transcriptional corepressor Transcription factor 7 (T-cell specific, HMG-box) Uncharacterized protein	A0A1D5NYE8 A0A1D5P5C3 A0A1D5PQ44 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TTV3 A0A3Q2UDI2 A0A3Q3B1W2 E1BWE1 F1N8Z4 F1NDB6 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 P84247 Q5ZIL1 Q5ZLM0 Q5ZLX3 Q9PSW9	BCL9 CDC73 CTNNB1 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L LEF1 LOC100859381 LOC426037 PYGO1 RBBP5 RCJMB04_25e24 RUVBL1 TCF7 TLE1 TLE3	Gallus gallus (chicken)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A1D5PEZ2 A3R0S3 E1C021 P25429 Q91987	BDNF FRS2 GRB2 NTRK2 SOS1 TRKB	Gallus gallus (chicken)
NTRK2 activates RAC1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase	A0A3Q2U639 P25429 Q6LC82 Q91987	BDNF FYN NTRK2 TRKB cRac1A	Gallus gallus (chicken)
Activated NTRK2 signals through PLCG1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor	P25429 Q91987	BDNF NTRK2 TRKB	Gallus gallus (chicken)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 A0A1D5PNY8 E1AWU3 H9CX01 P0CG62 P79781 P84023 Q06900 Q5ZHY5 Q5ZJ16 Q5ZL33 Q8UWF3 Q90999	BAMBI ChALK5 LOC769000 MADH2 MADH3 PMEPA1 RPS27A SMAD3 SMAD7 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA80 UBB	Gallus gallus (chicken)
Processing of DNA double-strand break ends	BRISC and BRCA1-A complex member 2 Checkpoint protein Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 Fanconi anemia group J protein homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4 RAD1 checkpoint DNA exonuclease Rad9 RecQ-mediated genome instability protein 2 Replication factor A protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication protein A 14 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2	A0A1D5P2D1 A0A1D5P3M9 A0A1D5PSK5 A0A1D5PTJ5 A0A1D5PY49 A0A1L1RNY8 A0A1L1RUB9 A0A3Q2UDI2 A2IAR9 E1C4C7 F1NDD7 F1NJI2 F1P3C0 F1P4N0 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P53033 P62801 P63283 Q3YK19 Q5ZJJ2 Q5ZJM9 Q5ZKG3 Q5ZLH1 Q5ZM20 Q5ZML0 Q5ZMU6 Q76F79 Q9PSW9	BABAM2 BRE BRIP1 CCNA1 CCNA2 CDK2 DNA2 DNA2L FANCJ H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L HUS1 LOC100859381 LOC426037 PIAS4 PPP4R2 RAD1 RAD9A RCJMB04_6d17 RFC2 RFC3 RFC4 RMI2 RPA1 RPA3 SUMO2 TOPBP1 UBC9 UBCE9 UBE2I rad9	Gallus gallus (chicken)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	BRISC and BRCA1-A complex member 2 Eyes absent homolog Eyes absent homolog Eyes absent homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Polyubiquitin-B Protein inhibitor of activated STAT 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Stress-activated protein kinase JNK Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A1D5NXI7 A0A1D5P2D1 A0A1D5P546 A0A1D5PC43 A0A1D5PGP0 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TY19 A0A3Q2UDI2 E1C6D5 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P0CG62 P62801 P63283 P79781 Q5ZML0 Q8QGH2 Q9PSW9	BABAM2 BRE EYA1 EYA2 EYA4 H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KDM4A KDM4B LOC100859381 LOC426037 MAPK8 PIAS4 RPS27A SUMO1 UBA80 UBB UBC9 UBCE9 UBE2I	Gallus gallus (chicken)
Nonhomologous End-Joining (NHEJ)	BRISC and BRCA1-A complex member 2 Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Non-homologous end-joining factor 1 Protein artemis Protein inhibitor of activated STAT 4 Tyrosyl-DNA phosphodiesterase 2 X-ray repair cross complementing 4	A0A1D5P2D1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDC0 F1NDD7 F1NVP8 F1NW29 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P62801 Q5QJC2 Q5ZML0 Q9PSW9	BABAM2 BRE DCLRE1C H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 NHEJ1 PIAS4 SNM1C TDP2 XRCC4	Gallus gallus (chicken)
G2/M DNA damage checkpoint	BRISC and BRCA1-A complex member 2 Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4	A0A1D5P2D1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P62801 Q5ZML0 Q9PSW9	BABAM2 BRE H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PIAS4	Gallus gallus (chicken)
Basigin interactions	Basigin Caveolin Integrin alpha-6 Monocarboxylate transporter 1 Sodium/potassium-transporting ATPase subunit beta-3 interstitial collagenase	A0M8T8 E1C9D9 P17790 P26007 P33879 Q5ZLZ6	ATP1B3 BSG CAV1 ITGA6 MMP1 RCJMB04_4e8	Gallus gallus (chicken)
Integrin cell surface interactions	Basigin Collagen type IV alpha 1 chain Fibronectin Integrin alpha-6 Integrin beta Integrin subunit alpha 4 Integrin subunit alpha 9 Leukocyte surface antigen CD47 Lumican	A0A1D5P8P3 A0A1D5PKL9 A0A1D5PQP8 P11722 P17790 P26007 P51890 Q6XFR1 Q92071	BSG CD47 COL4A1 FN1 ITGA4 ITGA6 ITGA9 ITGB3 LDC LUM	Gallus gallus (chicken)
Proton-coupled monocarboxylate transport	Basigin Monocarboxylate transporter 1 Monocarboxylate transporter 2	F1NVU4 P17790 Q5ZLZ6	BSG RCJMB04_4e8 SLC16A7	Gallus gallus (chicken)
Keratan sulfate biosynthesis	Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Fibromodulin Hexosyltransferase Keratocan Lumican Mimecan Sulfotransferase	A0A1D5NTY7 A0A1D5NVT2 A0A1D5PSH8 A0A3S5ZPV4 O42235 P51890 Q11200 Q5ZK57 Q9W6H0	B3GNT2 B4GALT2 B4GALT6 CHST2 FMOD KERA LDC LUM OGN SIAT4A ST3GAL1	Gallus gallus (chicken)
O-linked glycosylation of mucins	Beta-1,4-galactosyltransferase C1GALT1 specific chaperone 1 Glucosaminyl (N-acetyl) transferase 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase	A0A1D5PGR9 A0A1D5PJE0 A0A3S5ZPV4 E1BSH4 E1C241 E1C421 F1NIE6 F1NU59 Q5F3G7 Q5F4C7 Q5ZJL1 Q5ZK57	B3GNT2 B3GNT5 B3GNT9 B4GALT6 C1GALT1 C1GALT1C1 GALNT1 GALNT3 GALNT7 GCNT1 GCNT4 RCJMB04_1b1	Gallus gallus (chicken)
A tetrasaccharide linker sequence is required for GAG synthesis	Beta-1,4-galactosyltransferase Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican-1 Syndecan-4 Syndecan Syndecan Xylosyltransferase 2	A0A1D5P9Q8 A0A1L1RX77 F1NU53 F1NV24 F1P150 P49416 Q2HPN7 Q8JIY0	B3GAT2 B4GAL-T7 DCN GPC1 SDC1 SDC2 SDC4 XYLT2	Gallus gallus (chicken)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Beta-2-microglobulin CD1.2 antigen CD300 molecule like family member g CD40 ligand CD48 CXADR Ig-like cell adhesion molecule Cell surface glycoprotein CD200 receptor 1-A Ig-like domain-containing protein Integrin subunit alpha 4 KRAB domain containing zinc finger protein MHC BF1 class I MHC class I alpha chain 2 Triggering receptor expressed on myeloid cells 2 Uncharacterized protein	A0A1D5PIR0 A0A1D5PKL9 A0A1D5PLP7 A0ZXL5 F1NBK7 F1NSL7 K4L906 P21611 Q2YHT7 Q52Z74 Q5ZKJ6 Q95601 Q9I8D8 R4GFS8	B-FIV B2M BF1 BF2 BFIV21 CD1.2 CD1A2 CD200R1A CD300LG CD40L CD40LG CD48 ITGA4 KRABZFP RCJMB04_10g5 TNFSF5 TREM2 TSTD1	Gallus gallus (chicken)
Hyaluronan uptake and degradation	Beta-hexosaminidase Calcineurin B homologous protein 1 Glucuronidase beta Lymphatic vessel endothelial hyaluronan receptor 1	A0A1L1RSD2 E1C9I1 F1NTQ2 Q5ZM44	CHP CHP1 GUSB HEXB LYVE1	Gallus gallus (chicken)	G35674CY
Keratan sulfate degradation	Beta-hexosaminidase Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	A0A1D5NTY7 F1NI04 F1NTQ2 O42235 P51890 Q9W6H0	FMOD GNS HEXB KERA LDC LUM OGN	Gallus gallus (chicken)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Generic Transcription Pathway	C2H2-type domain-containing protein Cyclin-C Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 7 Zinc finger protein 704 Zinc finger protein 706	A0A1D5NUC6 A0A1D5P8W2 A0A1D5PFE9 A0A1D5PK99 A0A1L1RJ75 E1BUI5 E1C6N9 F1NY10 P55168 Q5ZKY9 Q5ZMM5	CCNC LOC101747670 MED1 MED17 MED20 MED30 MED31 MED4 MED7 TRFP ZNF704 ZNF706	Gallus gallus (chicken)
Cell surface interactions at the vascular wall	CD48 CXADR Ig-like cell adhesion molecule Integrin subunit alpha 4 Invariant chain isoform p41 Joining chain of multimeric IgA and IgM Leukocyte surface antigen CD47 Macrophage migration inhibitory factor Uncharacterized protein	A0A1D5PIR0 A0A1D5PKL9 E1BY93 F1NSL7 K4L906 Q02960 Q6J613 Q6XFR1	CD47 CD48 ITGA4 Ii JCHAIN MIF TSTD1	Gallus gallus (chicken)
RNA Polymerase I Promoter Escape	CDK-activating kinase assembly factor MAT1 Chromobox 3 DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription factor IIH subunit 5 General transcription factor IIH subunit Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 TATA box-binding protein-associated factor RNA polymerase I subunit B TATA-box-binding protein	A0A1D5PEX8 A0A1D5PW04 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1BVP0 E1C9E6 F1NDD7 F1NHV9 F1NZ23 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q5ZJR9 Q5ZKH0 Q6JLB1 Q9PSW9 Q9PT88	CBX3 ERCC3 GTF2H2 GTF2H5 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 MNAT1 POLR1B POLR2E POLR2L RPB6 TAF1B TBP	Gallus gallus (chicken)
Termination of O-glycan biosynthesis	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	Q11200	SIAT4A ST3GAL1	Gallus gallus (chicken)

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