GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Oxidative Stress Induced Senescence	Cyclin dependent kinase 6 Cyclin dependent kinase inhibitor 2B Cyclin dependent kinase inhibitor 2C E3 ubiquitin-protein ligase RING2 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 MAPK activated protein kinase 2 MAPK activated protein kinase 3 Mitogen-activated protein kinase 9 Polycomb complex protein BMI-1 Polycomb protein EED Protein c-Fos RB binding protein 4, chromatin remodeling factor Stress-activated protein kinase JNK Thioredoxin mitogen-activated protein kinase kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase	A0A1D5NVP0 A0A1D5P1F4 A0A1D5PD64 A0A1D5PIQ5 A0A1D5PTJ8 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TY19 A0A3Q2U1E9 A0A3Q2UDI2 F1NCY7 F1NDD7 F1NLF9 F1P5G5 F2Z4M0 P02263 P02272 P08629 P0C1H3 P0C1H4 P0C1H5 P11939 P62801 P70082 P79996 P84229 P84247 Q5SDR3 Q5ZKH3 Q7ZT27 Q90771 Q9PSW9	BMI1 CDK6 CDKN2B CDKN2C EED FOS H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L JNK2 LOC100859381 LOC426037 MAP2K3 MAP2K4 MAP3K5 MAPK14 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 PCGF4 RBBP4 RNF2 TXN cdk6	Gallus gallus (chicken)
Myogenesis	BCL2 interacting protein 2 Cadherin-2 Catenin beta-1 Cell division control protein 42 homolog Mitogen-activated protein kinase 12 Myocyte enhancer factor 2D Myogenic factor 6 Myogenic factor Myogenic factor Myogenin mitogen-activated protein kinase	A0A1D5NYE8 A0A1D5NYL4 A0A1D5PIQ5 F1NEC1 F1NHM3 F1NLU9 P10288 P17920 Q01795 Q90694 R4GMI9	BNIP2 CDC42 CDH2 CTNNB1 MAPK12 MAPK14 MEF2D MRF4 MYF5 MYF6 MYOD1 MYOG	Gallus gallus (chicken)
Collagen chain trimerization	Collagen alpha-1(XVII) chain Collagen type I alpha 1 chain Collagen type I alpha 2 chain Collagen type III alpha 1 chain Collagen type XII alpha 1 chain	A0A1D5PE57 A0A1D5PYU1 A0A1L1RPW4 A0A5H1ZRJ7 Q90584	BP180 BPAG2 COL12A1 COL17A1 COL1A1 COL1A2 COL3A1	Gallus gallus (chicken)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Dual specificity mitogen-activated protein kinase kinase 1 Fibronectin GTPase HRas GTPase NRas IQ motif containing GTPase activating protein 1 Integrin beta Kinase suppressor of ras 2 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein Rap-1b Serine/threonine-protein kinase B-raf Vinculin small monomeric GTPase small monomeric GTPase	A0A1D5PIZ8 A0A1D5PT95 A0A1D5PX90 F1NSA8 P00523 P05625 P08642 P11722 P12003 Q04982 Q5F352 Q5ZHX1 Q5ZIF0 Q5ZLQ6 Q92071	BRAF FN1 HRAS HRAS1 IQGAP3 ITGB3 KRAS KSR2 MIL NRAS RAF1 RAP1A RAP1B RCJMB04_27f19 RMIL SRC VCL VINC1 YWHAB	Gallus gallus (chicken)
Integrin cell surface interactions	Basigin Collagen type IV alpha 1 chain Fibronectin Integrin alpha-6 Integrin beta Integrin subunit alpha 4 Integrin subunit alpha 9 Leukocyte surface antigen CD47 Lumican	A0A1D5P8P3 A0A1D5PKL9 A0A1D5PQP8 P11722 P17790 P26007 P51890 Q6XFR1 Q92071	BSG CD47 COL4A1 FN1 ITGA4 ITGA6 ITGA9 ITGB3 LDC LUM	Gallus gallus (chicken)
Proton-coupled monocarboxylate transport	Basigin Monocarboxylate transporter 1 Monocarboxylate transporter 2	F1NVU4 P17790 Q5ZLZ6	BSG RCJMB04_4e8 SLC16A7	Gallus gallus (chicken)
Nicotinate metabolism	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase NAD(+) kinase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	A0A1D5NZW2 A0A1D5PVT8 A0A1L1RQU5 E1BXJ1 E5G6H7	BST1 CD38 NADK NMNAT1 NMNAT2	Gallus gallus (chicken)
Creation of classical C3 convertase	Complement 4 Complement C1q B chain Complement C1q subcomponent subunit A Complement C1s subcomponent Complement factor B-like protease (Fragment) Ig lambda chain C region Ig lambda chain V-1 region Ig mu chain C region MAp19 MHC-linked complement C4 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein VH1 protein (Fragment) complement subcomponent C1r	A0A3Q2UG72 A0A8V0Z078 A2N884 F1NAB7 F1NH19 P01875 P04210 P20763 P81475 Q076D6 Q5F3N3 Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	C1QA C1QB C1R C4 C4-2 MASP2 MBL RCJMB04_11h6 VH1	Gallus gallus (chicken)
Initial triggering of complement	Collectin-10 Collectin-11 Complement C1q B chain Complement C1q C chain Mannose-binding protein Uncharacterized protein complement subcomponent C1r	A0A1D5PGB2 A0A1D5PIR0 A0A3Q3A736 F1NAB7 F1NH19 Q2LK95 Q98TA4	C1QB C1QC C1R CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
Complement Cascade	Complement 4 Complement C3 Complement C5 Complement factor B-like protease (Fragment) Complement regulatory GPI-anchor protein Complement regulatory membrane protein MHC-linked complement C4	A0A3Q2UG72 A0A8V1AM71 P81475 Q076D6 Q4AEI5 Q90633 Q9DEG0	C4 C4-2 C5 CREG Cremp	Gallus gallus (chicken)
Regulation of insulin secretion	ATP-sensitive inward rectifier potassium channel 11 Rap guanine nucleotide exchange factor 4 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 cAMP-dependent protein kinase	A0A1D5PMC0 A0A3Q3AHR0 E1BZF6 F1NBC9 O73700 R4GIN8	CACNA1D CACNB2 KCNJ11 LOC107050029 PRKACB RAPGEF4	Gallus gallus (chicken)	G58161NS
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Catenin beta-1 Frizzled class receptor 3 Frizzled-4 G protein subunit alpha transducin 2 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Lymphoid enhancer binding factor 1 Phosphodiesterase Protein Wnt-11 Protein Wnt Protein phospatase 3 regulatory subunit B alpha isoform type 1 Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma calcium/calmodulin-dependent protein kinase small monomeric GTPase	A0A1D5NTJ0 A0A1D5NYE8 A0A1D5NZL7 A0A1D5P7Z5 A0A1D5PLZ8 A0A1D5PT95 A0A1D5PZ45 A0A3Q2UEZ9 A0A3Q3B1W2 E1BW98 E1C1U6 E1C795 F1NA42 F1NGS8 F1NLV4 P49339 Q5ZJ03 Q6VN51 Q802E4 Q9IA05 Q9YGX6 R4GFT9 R4GKD1	CAMK2A CTNNB1 FZ4 FZD3 FZD4 GNAO1 GNAT2 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 KRAS LEF1 OXLD1 PDE6B PDE6b PLCB1 RCJMB04_23k16 WNT-11 WNT11 WNT5A	Gallus gallus (chicken)
Interferon gamma signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase	A0A1D5PS87 B6RCQ2 F1NGS8 F1NMJ9 F1P3G1 P49708 Q5ZJK3 R4GJH9	CAMK2A IFNG IFNGR2 JAK1 PRKCD RCJMB04_17i9 SOCS1 SOCS3	Gallus gallus (chicken)
Other interleukin signaling	Caspase-3 Interferon lambda receptor 1 Interferon lambda-3 Interleukin 34 Myelomonocytic growth factor Synaptosomal-associated protein 25 Syndecan Taxilin alpha Tyrosine-protein kinase	A0A3Q3B2W9 B4ER10 F1NMJ9 F1NV24 K9JA28 O93417 P13854 P60878 R4GIU3	CASP3 IFNL IFNL3 IFNLR1 IL28 IL28B IL28RA IL34 JAK1 SDC1 SNAP SNAP25 TXLNA	Gallus gallus (chicken)
Estrogen-dependent gene expression	Core-binding factor beta subunit DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Forkhead box A1 GATA-binding factor 3 General transcription facter IIA subunit 1 variant 1 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 Probable ATP-dependent RNA helicase DDX5 Protein c-Fos RNA polymerase II subunit C Runt-related transcription factor TATA-box-binding protein TLE family member 3, transcriptional corepressor Transcription initiation factor IIA subunit 2 YY2 transcription factor [histone H3]-trimethyl-L-lysine(9) demethylase peptidylprolyl isomerase	A0A1D5PCB1 A0A1D5PUH1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TTQ9 A0A3Q2U9P1 A0A3Q2UDI2 A0A3S5ZPN3 A1IIE5 A1IIE6 E1BSY6 E1BV97 F1NCB0 F1NDB6 F1NDD7 F1NHV6 F1NHV9 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P11939 P23825 P56517 P62801 P70082 P84229 P84247 Q5F393 Q6JLB1 Q9PSW9 Q9PT88 R4GIS3	CBFB DDX5 FKBP4 FOS FOXA1 GATA3 GTF2A1 GTF2A2 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L KDM4B LOC100859381 LOC426037 NCOA1 NR5A2 NRIP1 POLR2B POLR2C POLR2E POLR2L RPB6 RUNX1 TBP TLE3 YY2	Gallus gallus (chicken)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Core-binding factor beta subunit Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 RB binding protein 5, histone lysine methyltransferase complex subunit Runt-related transcription factor SIN3 transcription regulator family member A SIN3 transcription regulator family member B Uncharacterized protein	A0A1D5PY49 A0A1L1RNY8 A0A3Q2TTQ9 A0A3Q2UDI2 E1BX21 F1NDD7 F1NMJ8 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 P84247 Q5ZIL1 Q5ZLX3 Q9PSW9	CBFB H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L LOC100859381 LOC426037 RBBP5 RCJMB04_25e24 RUNX1 SIN3A SIN3B	Gallus gallus (chicken)
RNA Polymerase I Promoter Escape	CDK-activating kinase assembly factor MAT1 Chromobox 3 DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPB General transcription factor IIH subunit 5 General transcription factor IIH subunit Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 TATA box-binding protein-associated factor RNA polymerase I subunit B TATA-box-binding protein	A0A1D5PEX8 A0A1D5PW04 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1BVP0 E1C9E6 F1NDD7 F1NHV9 F1NZ23 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q5ZJR9 Q5ZKH0 Q6JLB1 Q9PSW9 Q9PT88	CBX3 ERCC3 GTF2H2 GTF2H5 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 MNAT1 POLR1B POLR2E POLR2L RPB6 TAF1B TBP	Gallus gallus (chicken)
Generic Transcription Pathway	C2H2-type domain-containing protein Cyclin-C Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 7 Zinc finger protein 704 Zinc finger protein 706	A0A1D5NUC6 A0A1D5P8W2 A0A1D5PFE9 A0A1D5PK99 A0A1L1RJ75 E1BUI5 E1C6N9 F1NY10 P55168 Q5ZKY9 Q5ZMM5	CCNC LOC101747670 MED1 MED17 MED20 MED30 MED31 MED4 MED7 TRFP ZNF704 ZNF706	Gallus gallus (chicken)
Cell surface interactions at the vascular wall	CD48 CXADR Ig-like cell adhesion molecule Integrin subunit alpha 4 Invariant chain isoform p41 Joining chain of multimeric IgA and IgM Leukocyte surface antigen CD47 Macrophage migration inhibitory factor Uncharacterized protein	A0A1D5PIR0 A0A1D5PKL9 E1BY93 F1NSL7 K4L906 Q02960 Q6J613 Q6XFR1	CD47 CD48 ITGA4 Ii JCHAIN MIF TSTD1	Gallus gallus (chicken)
Assembly of the pre-replicative complex	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Anaphase-promoting complex subunit CDC26 Cell division cycle protein 27 homolog DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 Fizzy/cell division cycle 20 related 1 Polyubiquitin-B Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Ubiquitin B Ubiquitin-conjugating enzyme E2 C Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PJW4 A0A3Q2UD09 E1BX02 E1C2U4 E1C6N0 F1NC02 F1NEQ6 F1NFJ0 F1NPQ0 F1NR71 H9L1Y1 P0CG62 P79781 P84169 Q5F3J5 Q5ZIT7 Q5ZJL3 Q5ZJX9 Q5ZK91 Q5ZKL0 Q5ZKR8 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 R4GJY8 R4GLB3	CDC26 FZR1 MCM3 MCM4 MCM5 PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 PSME3 PSMF1 RCJMB04_12e16 RCJMB04_14i9 RCJMB04_23k2 RCJMB04_9i8 RPS27A UBA80 UBB UBE2U cpsmb7	Gallus gallus (chicken)
RHO GTPases activate PAKs	Cell division control protein 42 homolog LIM domain kinase 1 Myosin light chain 12B Myosin regulatory light chain 2, smooth muscle major isoform Myosin regulatory light chain 2, smooth muscle minor isoform Myosin-9 Protein phosphatase 1 regulatory subunit 12A Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Uncharacterized protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A1D5PM19 A0A1L1RUU9 E1BS97 E1C3P6 F1N8W8 P02612 P24032 P62207 Q5ZJB0 Q6LC82 Q8QFP8 Q90623 Q90694	CDC42 LIMK1 MBS MYH9 MYL12B MYPT1 PAK1 PAK2 PAK3 PPP1CB PPP1R12A RCJMB04_19i21 cRac1A	Gallus gallus (chicken)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Hematopoietic prostaglandin D synthase Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2	A0A1D5PM03 E2IPN6 O73888 P27607	CEF-147 GSTS HPGDS PGDS PTGDS2 PTGES PTGS1 PTGS2	Gallus gallus (chicken)
Nicotinamide salvaging	NAD-capped RNA hydrolase NUDT12 Nicotinamide phosphoribosyltransferase Prostaglandin G/H synthase 2 Sodium-coupled monocarboxylate transporter 1	E1C2E5 F1P5L0 P27607 Q58I02	CEF-147 NAMPTP1 NUDT12 PBEF1 PTGS2 SLC5A8	Gallus gallus (chicken)
Biosynthesis of DHA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)

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