GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **263** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Phospholipase C-mediated cascade: FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1	Gallus gallus (chicken)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P19596 P21804 P48800 P48801 Q4R0X9 Q5F352 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 2 Leucine-rich repeat transmembrane protein FLRT3	A0A3Q2TTH8 E1BZW7 E1C6W5 F1NUK7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FLRT2 FLRT3	Gallus gallus (chicken)
Negative regulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Polyubiquitin-B Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P0CG62 P19596 P21804 P48800 P48801 P79781 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PTPN11 RPS27A UBA80 UBB	Gallus gallus (chicken)
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P08642 P19596 P21804 P48800 P48801 Q4R0X9 Q5F352 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
PI3K Cascade	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1P5Y5 P18460 P18461 P19596 P21804 P48800 P48801 Q197G3 Q4R0X9 Q5F4A2 Q5KRA4 Q90687 Q9I950 R4GIR0 R4GMB5	CEK1 CEK2 CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 Fgf16 Fgf7 GRB2 PIK3CB PIK3R1 PIK3R2 PTPN11	Gallus gallus (chicken)
FGFR3b ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor	P18460 P19596 Q4R0X9 Q9I950	CEK2 FGF-18 FGF1 FGF18 FGF8 FGFR3	Gallus gallus (chicken)
Phospholipase C-mediated cascade; FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	E1BZW7 P18460 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16	Gallus gallus (chicken)
FGFR3c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Polypeptide N-acetylgalactosaminyltransferase	E1BZW7 E1C241 P18460 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16 GALNT3	Gallus gallus (chicken)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A3R0S3 E1BZW7 P08642 P18460 P19596 P48800 Q197G3 Q4R0X9 Q5F352 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
Negative regulation of FGFR3 signaling	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Polyubiquitin-B Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A3R0S3 E1BZW7 E1C021 P0CG62 P18460 P19596 P48800 P79781 Q197G3 Q4R0X9 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 PTPN11 RPS27A UBA80 UBB	Gallus gallus (chicken)
PI-3K cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 P18460 P19596 P48800 Q197G3 Q4R0X9 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A3R0S3 E1BZW7 E1C021 P08642 P18460 P19596 P48800 Q197G3 Q4R0X9 Q5F352 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
FGFR2c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	E1BZW7 F1P5Y5 P18461 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK3 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF6 FGF8 FGFR2 Fgf16	Gallus gallus (chicken)
FGFR1c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Transforming growth factor beta receptor 3	E1BZW7 F1P5Y5 P19596 P21804 P48800 Q4R0X9 Q90998 R4GIR0	CEK1 FGF1 FGF2 FGF23 FGF4 FGF6 FGF8 FGFR1 TGFBR3	Gallus gallus (chicken)
EPH-Ephrin signaling	Ephrin A2 Ephrin type-A receptor 4 Ephrin type-A receptor 7 Ephrin-B1 Ephrin-B2 receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A1D5NZN5 A0A1D5P9X0 F1NJX6 F1NSE6 O42422 Q07496 Q9PUJ4	CEK11 CEK8 EFNA2 EFNB1 EFNB2 EPHA3 EPHA4 EPHA5 EPHA7	Gallus gallus (chicken)
Gluconeogenesis	Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate mutase 1 Solute carrier family 37 member 4 Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 F1NKP4 F1NTA5 F1NTH9 P00356 P00940 P07341 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 G6PC2 GAPD GAPDH GPI PCK1 PGAM1 SLC37A4 TPI1	Gallus gallus (chicken)	G58161NS
HATs acetylate histones	E3 ubiquitin-protein ligase MSL2 Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone acetyltransferase type B catalytic subunit MSL complex subunit 3 Nuclear receptor coactivator Paired box 3	A0A1D5NVS8 A0A1D5PS75 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1P5A3 P02263 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 Q5F393 Q8QGS3 Q9PSW9	H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HAT1 HIST1H2B5L LOC426037 MSL2 MSL3 NCOA1 PAX3 Pax3	Gallus gallus (chicken)
O-linked glycosylation	Dolichyl-phosphate-mannose--protein mannosyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2	F1NMM0 Q5NDE8	AGO61 GTDC2 POMGNT2 POMT1	Gallus gallus (chicken)
RET signaling	Docking protein 1 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0E4BA89 A0A1D5NYP8 A0A1D5P405 A0A1D5PEZ2 A0A1D5PZ39 A0A3Q3ACS4 A3R0S3 E1C021 E1C2C5 F1NHX1 O13156 P00523 Q5F4A2 Q90687 R4GHL2	DOK1 FRS2 GDNFRA GFRA1 GRB10 GRB2 PDLIM7 PIK3CB PIK3CD PIK3R1 PIK3R2 PRKCA PTPN11 SHC1 SOS1 SRC	Gallus gallus (chicken)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Pro-glucagon	A0A1D5P7Z5 A0A1D5PJA5 E1C1U6 F1NLV4 F1P3R0 M9NJI3 P01295 P68259	DPP4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP	Gallus gallus (chicken)	G58161NS
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
Effects of PIP2 hydrolysis	Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor Protein kinase C delta type Protein kinase C Transient receptor potential cation channel subfamily C member 7	A0A1D5PLX8 F1NDU2 F1NJH1 F1NYQ1 F1P1X4 F1P3G1	DGKB DGKK ITPR2 PRKCD PRKCH TRPC7	Gallus gallus (chicken)
The canonical retinoid cycle in rods (twilight vision)	Dehydrogenase/reductase 9 Lecithin retinol acyltransferase Retinaldehyde-binding protein 1 Retinol dehydrogenase 11 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A1I7Q422 E1BTL3 E1C1U1 E1C781 F1P3Y2 F1P4T5 P41263	CRALBP LOC121106449 LRAT RBP4 RDH11 RHO RLBP1 TTR	Gallus gallus (chicken)

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