GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
GRB2 events in EGFR signaling	Amphiregulin Betacellulin Epigen Epiregulin GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PKH0 A0A1D5PT95 A3R0S3 F1NJR9 P08642 Q5EG71 Q5F352 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL HRAS HRAS1 KRAS NRAS SOS1	Gallus gallus (chicken)
Signaling by PDGF	Collagen type IV alpha 1 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor subunit A Thrombospondin 4 furin	A0A1D5P8P3 A0A3Q2U6E1 E1C209 F1NBP0 F1NWX6 Q90WK2 Q91000 Q9I946	COL4A1 FURIN PDGF-A (L) PDGFA PDGFC PDGFD PLAT PLG SCDGF THBS4	Gallus gallus (chicken)
IFNG signaling activates MAPKs	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase	A0A1D5PS87 F1NMJ9 P05625 P49708	IFNG IFNGR2 JAK1 MIL RAF1	Gallus gallus (chicken)
The NLRP3 inflammasome	Pannexin SGT1 homolog, MIS12 kinetochore complex assembly cochaperone Thioredoxin	A0A1D5P0I0 F1NAS0 P08629	PANX PANX1 SUGT1 TXN	Gallus gallus (chicken)
FGFR2c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	E1BZW7 F1P5Y5 P18461 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK3 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF6 FGF8 FGFR2 Fgf16	Gallus gallus (chicken)
ESR-mediated signaling	peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q2U9P1 Q646T7	FKBP4 FKBP5 FKBP51	Gallus gallus (chicken)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 2 Leucine-rich repeat transmembrane protein FLRT3	A0A3Q2TTH8 E1BZW7 E1C6W5 F1NUK7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FLRT2 FLRT3	Gallus gallus (chicken)
Activated NTRK3 signals through PI3K	NT-3 growth factor receptor Neurotrophin-3 Proto-oncogene tyrosine-protein kinase Src	A0A3Q2U804 P00523 Q91044	NTF3 NTRK3 SRC TRKC	Gallus gallus (chicken)
PI3K Cascade	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1P5Y5 P18460 P18461 P19596 P21804 P48800 P48801 Q197G3 Q4R0X9 Q5F4A2 Q5KRA4 Q90687 Q9I950 R4GIR0 R4GMB5	CEK1 CEK2 CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 Fgf16 Fgf7 GRB2 PIK3CB PIK3R1 PIK3R2 PTPN11	Gallus gallus (chicken)
Post-translational protein phosphorylation	Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-L-fucosidase Amyloid beta like protein 2 Apolipoprotein A-I Beta-galactoside-binding lectin Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Endoplasmin Fibroblast growth factor Fibronectin Insulin-like growth factor-binding protein 5 Interleukin-6 Matrilin-3 Matrix remodeling-associated protein 8 Milk fat globule EGF and factor V/VIII domain containing Ovocleidin-116 PNPLA2/ATGL Proenkephalin Reticulocalbin 1 Serine protease 23 Serpin family D member 1 Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan Uncharacterized protein	A0A1D5NW68 A0A1D5PLZ2 A0A1D5PPN9 B3TZB4 E1BRJ2 E1BS94 E1BXF4 E1C0K5 E1C0T2 E1C652 E1C744 F1ND88 F1NSM7 F1P053 F1P0A7 O42401 P07583 P08250 P10288 P11722 P19336 Q5F3N4 Q5F407 Q8JGM4 Q8JIY0 Q90WI4 Q90YI0 R4GIR0 R4GLT1	ALB APLP2 APOA1 BMP4 CCN1 CDH2 CG-1B CST3 CYR61 DNAJC3 FGF23 FN1 FUCA2 HSP90B1 IGFBP5 IL6 MATN3 MFGE8 MGAT4A MXRA8 PENK PNPLA2 PRSS23 QSCN6 QSOX QSOX1 RCJMB04_11h1 RCN1 SDC2 SERPIND1 SOX STC2	Gallus gallus (chicken)
O-linked glycosylation	Dolichyl-phosphate-mannose--protein mannosyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2	F1NMM0 Q5NDE8	AGO61 GTDC2 POMGNT2 POMT1	Gallus gallus (chicken)
GP1b-IX-V activation signalling	14-3-3 protein zeta Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Phosphatidylinositol 3-kinase regulatory subunit alpha Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Tsukushi	A0A3Q3ACS4 A0A3Q3AXX7 F1P1G3 P00523 P05625 Q5ZKC9 Q65Z91	GP1BB GP9 LRRC54 MIL PIK3R1 RAF1 SRC TSK TSKU YWHAZ	Gallus gallus (chicken)
The canonical retinoid cycle in rods (twilight vision)	Dehydrogenase/reductase 9 Lecithin retinol acyltransferase Retinaldehyde-binding protein 1 Retinol dehydrogenase 11 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A1I7Q422 E1BTL3 E1C1U1 E1C781 F1P3Y2 F1P4T5 P41263	CRALBP LOC121106449 LRAT RBP4 RDH11 RHO RLBP1 TTR	Gallus gallus (chicken)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Pannexin	A0A1D5P0I0 P18861 Q8UVE3	GJA7 GJC1 GJD2 PANX PANX1	Gallus gallus (chicken)
Fibronectin matrix formation	Fibronectin	P11722	FN1	Gallus gallus (chicken)
Interferon gamma signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase	A0A1D5PS87 B6RCQ2 F1NGS8 F1NMJ9 F1P3G1 P49708 Q5ZJK3 R4GJH9	CAMK2A IFNG IFNGR2 JAK1 PRKCD RCJMB04_17i9 SOCS1 SOCS3	Gallus gallus (chicken)
Signaling by Activin	Activin receptor type-2A Inhibin beta B chain Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase	A0A1D5NUH3 A0A3Q2TUT8 P84023 Q8UWF3 Q90669 Q90998 R4GIS0	ACVR1C ACVR2A INHBB LOC769000 MADH2 MADH3 SMAD3 TGFBR3	Gallus gallus (chicken)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	BRISC and BRCA1-A complex member 2 Eyes absent homolog Eyes absent homolog Eyes absent homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Polyubiquitin-B Protein inhibitor of activated STAT 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Stress-activated protein kinase JNK Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A1D5NXI7 A0A1D5P2D1 A0A1D5P546 A0A1D5PC43 A0A1D5PGP0 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TY19 A0A3Q2UDI2 E1C6D5 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P0CG62 P62801 P63283 P79781 Q5ZML0 Q8QGH2 Q9PSW9	BABAM2 BRE EYA1 EYA2 EYA4 H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KDM4A KDM4B LOC100859381 LOC426037 MAPK8 PIAS4 RPS27A SUMO1 UBA80 UBB UBC9 UBCE9 UBE2I	Gallus gallus (chicken)
FGFR1c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Transforming growth factor beta receptor 3	E1BZW7 F1P5Y5 P19596 P21804 P48800 Q4R0X9 Q90998 R4GIR0	CEK1 FGF1 FGF2 FGF23 FGF4 FGF6 FGF8 FGFR1 TGFBR3	Gallus gallus (chicken)
IRS-related events triggered by IGF1R	Insulin-like growth factor I Insulin-like growth factor II	P18254 P33717	IGF1 IGF2	Gallus gallus (chicken)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin V Ovalbumin	F1NYJ1 P01012	CTSV SERPINB14	Gallus gallus (chicken)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P08642 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5F352 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
PI-3K cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 P18460 P19596 P48800 Q197G3 Q4R0X9 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 A0A1D5PNY8 E1AWU3 H9CX01 P0CG62 P79781 P84023 Q06900 Q5ZHY5 Q5ZJ16 Q5ZL33 Q8UWF3 Q90999	BAMBI ChALK5 LOC769000 MADH2 MADH3 PMEPA1 RPS27A SMAD3 SMAD7 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA80 UBB	Gallus gallus (chicken)

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