GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **263** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Iron uptake and transport	Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase Ferritin heavy chain Iron-responsive element-binding protein 2 Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Proton-coupled folate transporter S-phase kinase-associated protein 1 Solute carrier family 40 member Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P2L3 A0A1D5P546 A0A1D5PBJ1 A0A1D5PQ17 A0A1D5PQV0 F1NHL2 F1NJ67 P08267 P0CG62 P79781 Q5F3K3 Q5ZKF5	ACO1 CAND1 CUL1 CYBRD1 FTH IREB2 PCFT RPS27A SKP1 SKP1A SLC40A1 SLC46A1 UBA80 UBB	Gallus gallus (chicken)
Keratan sulfate biosynthesis	Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Fibromodulin Hexosyltransferase Keratocan Lumican Mimecan Sulfotransferase	A0A1D5NTY7 A0A1D5NVT2 A0A1D5PSH8 A0A3S5ZPV4 O42235 P51890 Q11200 Q5ZK57 Q9W6H0	B3GNT2 B4GALT2 B4GALT6 CHST2 FMOD KERA LDC LUM OGN SIAT4A ST3GAL1	Gallus gallus (chicken)
Keratan sulfate degradation	Beta-hexosaminidase Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	A0A1D5NTY7 F1NI04 F1NTQ2 O42235 P51890 Q9W6H0	FMOD GNS HEXB KERA LDC LUM OGN	Gallus gallus (chicken)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Lactose synthesis	Lysozyme C	P00698	LYZ	Gallus gallus (chicken)	G58161NS G74621DY
Lectin pathway of complement activation	Collectin-10 Collectin-11 Mannose-binding protein	A0A3Q3A736 Q2LK95 Q98TA4	CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
Lectin-mediated initiation of complement cascade	MAp19 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein	Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	MASP2 MBL	Gallus gallus (chicken)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase	E1BZG7 E1C2U3 E1C4T5 Q8UWB9 Q8UWC1	B3GALT1 B3GALT5 CFTII FUT10 FUT7 FUT9 cFuc-TIX	Gallus gallus (chicken)	G90387AM
Lysosomal oligosaccharide catabolism				Gallus gallus (chicken)	G00027MO G25577BM G28233ME G70323CJ G90333CG
MAP2K and MAPK activation	14-3-3 protein beta/alpha Dual specificity mitogen-activated protein kinase kinase 1 Fibronectin GTPase HRas GTPase NRas IQ motif containing GTPase activating protein 1 Integrin beta Kinase suppressor of ras 2 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein Rap-1b Serine/threonine-protein kinase B-raf Vinculin small monomeric GTPase small monomeric GTPase	A0A1D5PIZ8 A0A1D5PT95 A0A1D5PX90 F1NSA8 P00523 P05625 P08642 P11722 P12003 Q04982 Q5F352 Q5ZHX1 Q5ZIF0 Q5ZLQ6 Q92071	BRAF FN1 HRAS HRAS1 IQGAP3 ITGB3 KRAS KSR2 MIL NRAS RAF1 RAP1A RAP1B RCJMB04_27f19 RMIL SRC VCL VINC1 YWHAB	Gallus gallus (chicken)
MHC class II antigen presentation	ADP-ribosylation factor AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-2 complex subunit alpha AP-2 complex subunit mu Cathepsin D Cathepsin V Clathrin light chain Endophilin-A1 Invariant chain isoform p41 MHC class II beta chain 2 Major histocompatibility complex class II beta chain BLB1 Peptidase C1A papain C-terminal domain-containing protein	A0A1D5NV94 A0A1D5PLI8 A0A3Q2U5N2 A5HUL4 F1NDA9 F1NHS7 F1NN08 F1NYJ1 Q05744 Q5ZMG7 Q5ZMK0 Q5ZMP6 Q6J613 Q8AXV1	AP1G1 AP1M1 AP1S2 AP2A2 AP2M1 ARF1 BLB1 BLB2 CLTA CTSD CTSV Ii RCJMB04_1m17 SH3GL2 SH3P4	Gallus gallus (chicken)
Metabolism of Angiotensinogen to Angiotensins	Cathepsin D Neprilysin	Q05744 Q67BJ2	CTSD MME	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
Metal ion SLC transporters	Natural resistance-associated macrophage protein 1 Solute carrier family 40 member Solute carrier family 41 member Solute carrier family 41 member	E1C334 F1NWZ7 P51027 Q5F3K3	NRAMP1 SLC11A1 SLC40A1 SLC41A1 SLC41A2	Gallus gallus (chicken)
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Leucine rich repeat containing 8 VRAC subunit C Leucine rich repeat containing 8 VRAC subunit D Lysosomal amino acid transporter 1 homolog NIPA like domain containing 3 Non imprinted in Prader-Willi/Angelman syndrome 2	A0A3Q2TZ76 E1BQK4 E1BR96 E1BYZ5 E1BZK2 E1C957 F1NBX2 Q5ZJX0	ANKH LOC107056693 LRRC8A LRRC8C LRRC8D NIPA2 NIPAL3 PQLC2 SLC66A1	Gallus gallus (chicken)
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor	F1P0I0 P30372	CHRM2 CHRM5 CM2	Gallus gallus (chicken)
MyD88 cascade initiated on plasma membrane	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 Phase 2 flagellin Toll-like receptor 2 Toll-like receptor 5	A5HNF6 P06179 P52616 Q2XQ10 Q5F382 Q5GR02 Q5ZJM6	H2 MYD88 RCJMB04_17b10 RCJMB04_29d24 TLR15 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
MyD88:TIRAP-dependent cascade initiated on plasma membrane	Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 4 Toll/interleukin-1 receptor domain-containing adapter protein	A0A8V0XHS1 A5H0S2 A5HNF6 Q4U127 Q5F382 Q5WA51 Q5ZJM6 Q7ZTG5 Q9DD78	LY96 MYD88 RCJMB04_17b10 RCJMB04_29d24 TIRAP TLR1 TLR1Lb TLR2-1 TLR4	Gallus gallus (chicken)
Myogenesis	BCL2 interacting protein 2 Cadherin-2 Catenin beta-1 Cell division control protein 42 homolog Mitogen-activated protein kinase 12 Myocyte enhancer factor 2D Myogenic factor 6 Myogenic factor Myogenic factor Myogenin mitogen-activated protein kinase	A0A1D5NYE8 A0A1D5NYL4 A0A1D5PIQ5 F1NEC1 F1NHM3 F1NLU9 P10288 P17920 Q01795 Q90694 R4GMI9	BNIP2 CDC42 CDH2 CTNNB1 MAPK12 MAPK14 MEF2D MRF4 MYF5 MYF6 MYOD1 MYOG	Gallus gallus (chicken)
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase	A0A1D5PEI3 A0A1D5PSH8 A0A3S5ZPV4 F1NEL5 Q5F407 Q6ZXD0 R4GKF3	B4GALT2 B4GALT6 LOC427873 MGAT4A MGAT5 SIAT8C ST8SIA6	Gallus gallus (chicken)	G81533KY
N-glycan trimming and elongation in the cis-Golgi				Gallus gallus (chicken)	G58161NS
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Autocrine motility factor receptor Polyubiquitin-B Transitional endoplasmic reticulum ATPase Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 F1NBB7 P0CG62 P79781 Q5ZMU9	AMFR RPS27A UBA80 UBB VCP vcp	Gallus gallus (chicken)	G03934XO G25577BM G28233ME G51034LA G86419OL
NF-kB is activated and signals survival	Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Sequestosome 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 16 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PLN4 E1C626 P0CG62 P18519 P79781 Q04861	NFKB1 NGFR RPS27A SQSTM1 TNFRSF16 TRAF6 UBA80 UBB	Gallus gallus (chicken)
NFG and proNGF binds to p75NTR	Tumor necrosis factor receptor superfamily member 16	P18519	NGFR TNFRSF16	Gallus gallus (chicken)
NFkB and MAPK activation mediated by TRAF6	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 PPM-type phosphatase domain-containing protein Phase 2 flagellin Polyubiquitin-B TNF receptor-associated factor Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 5 Toll/interleukin-1 receptor domain-containing adapter protein Ubiquitin-ribosomal protein eL40 fusion protein (Fragment) Ubiquitin-ribosomal protein eS31 fusion protein	A0A8V0XHS1 A5H0S2 A5HNF6 E1C626 P06179 P0CG62 P52616 P62985 P79781 Q2XQ10 Q4U127 Q5F382 Q5GR02 Q5WA51 Q5ZJM6 Q5ZJW3 Q7ZTG5 Q9DD78	H2 LY96 MYD88 RCJMB04_15c17 RCJMB04_17b10 RCJMB04_29d24 RPS27A TIRAP TLR1 TLR15 TLR1Lb TLR2-1 TLR4 TLR5 TRAF6 UBA52 UBA80 UBB UBCEP2 flaF fliC fljB hag	Gallus gallus (chicken)
NRIF signals cell death from the nucleus	Polyubiquitin-B Presenilin-1 Presenilin Sequestosome 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 16 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PLN4 E1C626 F1NGP7 P0CG62 P18519 P79781 Q4JIM4	NGFR PSEN1 PSEN2 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA80 UBB	Gallus gallus (chicken)

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