GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **263** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Hematopoietic prostaglandin D synthase Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2	A0A1D5PM03 E2IPN6 O73888 P27607	CEF-147 GSTS HPGDS PGDS PTGDS2 PTGES PTGS1 PTGS2	Gallus gallus (chicken)
RHO GTPases activate PAKs	Cell division control protein 42 homolog LIM domain kinase 1 Myosin light chain 12B Myosin regulatory light chain 2, smooth muscle major isoform Myosin regulatory light chain 2, smooth muscle minor isoform Myosin-9 Protein phosphatase 1 regulatory subunit 12A Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Uncharacterized protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A1D5PM19 A0A1L1RUU9 E1BS97 E1C3P6 F1N8W8 P02612 P24032 P62207 Q5ZJB0 Q6LC82 Q8QFP8 Q90623 Q90694	CDC42 LIMK1 MBS MYH9 MYL12B MYPT1 PAK1 PAK2 PAK3 PPP1CB PPP1R12A RCJMB04_19i21 cRac1A	Gallus gallus (chicken)
Regulation of insulin secretion	ATP-sensitive inward rectifier potassium channel 11 Rap guanine nucleotide exchange factor 4 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 cAMP-dependent protein kinase	A0A1D5PMC0 A0A3Q3AHR0 E1BZF6 F1NBC9 O73700 R4GIN8	CACNA1D CACNB2 KCNJ11 LOC107050029 PRKACB RAPGEF4	Gallus gallus (chicken)	G58161NS
Interleukin-20 family signaling	Interferon lambda receptor 1 Interferon lambda-3 Interleukin 22 receptor subunit alpha 1 Interleukin 22 Interleukin family protein Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A1D5PNV3 B4ER10 E1BRV0 E1C1U2 E1C5G0 F1NMJ9 K9JA28 Q5ZJK3 Q6DV79 Q90687	IFNL IFNL3 IFNLR1 IL22 IL22RA1 IL28 IL28B IL28RA JAK1 LOC107055197 PTPN11 RCJMB04_17i9 STAT3 STAT4	Gallus gallus (chicken)
Scavenging by Class A Receptors	Apolipoprotein A-I Collectin-11 Endoplasmin	A0A1D5PPN9 A0A3Q3A736 P08250	APOA1 COLEC11 HSP90B1	Gallus gallus (chicken)	G70323CJ G82576YO
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Mannosyltransferase N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	A0A1D5PQ50 A0A1L1RT72 F1P077	ALG12 DPAGT1	Gallus gallus (chicken)
ECM proteoglycans	Decorin Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin subunit alpha 9 Matrilin-3	A0A1D5PQP8 A0A1L1RX77 O42401 P07354 Q92071	CRTL1 DCN HAPLN1 ITGA9 ITGB3 MATN3	Gallus gallus (chicken)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor X Osteocalcin furin	A0A1D5PRL0 P25155 Q91000	BGLAP F10 FURIN FX	Gallus gallus (chicken)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor X Osteocalcin	A0A1D5PRL0 P25155	BGLAP F10 FX	Gallus gallus (chicken)
Interferon gamma signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase	A0A1D5PS87 B6RCQ2 F1NGS8 F1NMJ9 F1P3G1 P49708 Q5ZJK3 R4GJH9	CAMK2A IFNG IFNGR2 JAK1 PRKCD RCJMB04_17i9 SOCS1 SOCS3	Gallus gallus (chicken)
Regulation of IFNG signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase	A0A1D5PS87 B6RCQ2 F1NMJ9 P49708 Q5ZJK3 Q8QGH2 R4GJH9	IFNG IFNGR2 JAK1 RCJMB04_17i9 SOCS1 SOCS3 SUMO1	Gallus gallus (chicken)
IFNG signaling activates MAPKs	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase	A0A1D5PS87 F1NMJ9 P05625 P49708	IFNG IFNGR2 JAK1 MIL RAF1	Gallus gallus (chicken)
TNFR2 non-canonical NF-kB pathway	B-cell-activating factor BAFF CD40 ligand TNF receptor superfamily member 1B TNF receptor-associated factor	A0A1D5PTU3 A0A3Q3AAA5 Q8JHJ4 Q9I8D8	BAFF CD40L CD40LG TNFRSF1B TNFSF13B TNFSF5 TRAF3	Gallus gallus (chicken)
Response to elevated platelet cytosolic Ca2+	Protein kinase C Protein kinase C	A0A1D5PUY5 R4GHL2	PRKCA PRKCB	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 DEK proto-onco DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Splicing factor 3b subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit B TATA-box-binding protein	A0A1D5PW04 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1C2C3 F1NDD7 F1NHV9 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P60706 P62801 P70082 P84229 P84247 Q5F422 Q5ZJR9 Q6JLB1 Q9PSW9 Q9PT88	ACTB DEK H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 POLR1B POLR2E POLR2L RPB6 SF3B1 TAF1B TBP	Gallus gallus (chicken)
Transcriptional regulation by small RNAs	Argonaute 1, RISC catalytic component DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 GTP-binding nuclear protein Ran Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Nucleoporin 155 Nucleoporin 37 Nucleoporin 43 Nucleoporin 50 Nucleoporin 54 Nucleoporin 58 Nucleoporin NUP42 RNA polymerase II subunit C	A0A1D5PXD8 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1BV97 E1BYD2 E1C370 F1NCB0 F1NDD7 F1NHV9 F1NPS0 F1NSL1 F1NZ34 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P42558 P62801 P70082 P84229 P84247 Q5F473 Q5ZKL1 Q9PSW9 Q9PT88	AGO1 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 NUP155 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 POLR2B POLR2C POLR2E POLR2L RAN RPB6	Gallus gallus (chicken)
GABA receptor activation	GABA(C) receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit beta-4 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid type A receptor subunit gamma3	A0A1D5PXS3 F1ND90 F1NXA6 F6SVX7 P19019 P19150 P21548 P24045 Q90845	GABRA1 GABRA2 GABRA6 GABRB2 GABRB3 GABRB4 GABRG2 GABRG3 GABRR2	Gallus gallus (chicken)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Core-binding factor beta subunit Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 RB binding protein 5, histone lysine methyltransferase complex subunit Runt-related transcription factor SIN3 transcription regulator family member A SIN3 transcription regulator family member B Uncharacterized protein	A0A1D5PY49 A0A1L1RNY8 A0A3Q2TTQ9 A0A3Q2UDI2 E1BX21 F1NDD7 F1NMJ8 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 P84247 Q5ZIL1 Q5ZLX3 Q9PSW9	CBFB H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L LOC100859381 LOC426037 RBBP5 RCJMB04_25e24 RUNX1 SIN3A SIN3B	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein H Centromere protein I Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein S Centromere protein T Centromere protein W Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Opa interacting protein 5 Protein Mis18-alpha RB binding protein 4, chromatin remodeling factor RuvB-like helicase	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BQA1 E1BQA3 E1BSW7 F1N8S4 F1N8Z4 F1NDD7 F1NPG5 F1P5G5 F2Z4M0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P0DJH6 P62801 P70082 Q1T765 Q1T7B9 Q1T7C0 Q8AYS7 Q90ZF9 Q9PSW9	APITD1 CENPH CENPI CENPL CENPM CENPN CENPO CENPS CENPT CENPW H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 MIS18A OIP5 RBBP4 RUVBL1	Gallus gallus (chicken)
RNA Polymerase I Promoter Opening	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037	Gallus gallus (chicken)
Regulation of IFNA/IFNB signaling	Interferon alpha Interferon type A1/A2 Interferon type B Interferon Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 protein-tyrosine-phosphatase	A0A1I7Q402 B0FLN7 F1NMJ9 P42165 Q5ZJK3 Q90687 Q90873 Q9PWI5	IFN-gamma IFN2 IFNA IFNA1 IFNA2 IFNA3 IFNB JAK1 LOC100857947 LOC100858506 LOC100859414 LOC768614 PTPN1 PTPN11 RCJMB04_17i9	Gallus gallus (chicken)
The canonical retinoid cycle in rods (twilight vision)	Dehydrogenase/reductase 9 Lecithin retinol acyltransferase Retinaldehyde-binding protein 1 Retinol dehydrogenase 11 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A1I7Q422 E1BTL3 E1C1U1 E1C781 F1P3Y2 F1P4T5 P41263	CRALBP LOC121106449 LRAT RBP4 RDH11 RHO RLBP1 TTR	Gallus gallus (chicken)
Assembly of active LPL and LIPC lipase complexes	Lipoprotein lipase Uncharacterized protein furin	A0A1L1RJC1 P11602 Q91000	FURIN LOC101747868 LPL	Gallus gallus (chicken)

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