GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **263** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
FGFR3b ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor	P18460 P19596 Q4R0X9 Q9I950	CEK2 FGF-18 FGF1 FGF18 FGF8 FGFR3	Gallus gallus (chicken)
PI3K Cascade	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1P5Y5 P18460 P18461 P19596 P21804 P48800 P48801 Q197G3 Q4R0X9 Q5F4A2 Q5KRA4 Q90687 Q9I950 R4GIR0 R4GMB5	CEK1 CEK2 CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 Fgf16 Fgf7 GRB2 PIK3CB PIK3R1 PIK3R2 PTPN11	Gallus gallus (chicken)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P08642 P19596 P21804 P48800 P48801 Q4R0X9 Q5F352 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
Negative regulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Polyubiquitin-B Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P0CG62 P19596 P21804 P48800 P48801 P79781 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PTPN11 RPS27A UBA80 UBB	Gallus gallus (chicken)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 2 Leucine-rich repeat transmembrane protein FLRT3	A0A3Q2TTH8 E1BZW7 E1C6W5 F1NUK7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FLRT2 FLRT3	Gallus gallus (chicken)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P19596 P21804 P48800 P48801 Q4R0X9 Q5F352 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
Phospholipase C-mediated cascade: FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1	Gallus gallus (chicken)
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Transforming growth factor beta receptor 3	A0A3Q2TTH8 P19596 P21804 P48800 P48801 Q90998	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF3 FGFR1 TGFBR3	Gallus gallus (chicken)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P08642 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5F352 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
Negative regulation of FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Polyubiquitin-B Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A3Q2TTH8 A3R0S3 E1BZW7 E1C021 F1P5Y5 P0CG62 P18461 P19596 P48800 P48801 P79781 Q197G3 Q4R0X9 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 PTPN11 RPS27A UBA80 UBB	Gallus gallus (chicken)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5F352 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
Phospholipase C-mediated cascade; FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7	Gallus gallus (chicken)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor	A0A3Q2TTH8 P18461 P19596 P48801 Q5KRA4	CEK3 FGF-3 FGF1 FGF10 FGF3 FGF7 FGFR2 Fgf7	Gallus gallus (chicken)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor-like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 P48800 P48801 Q4R0X9 Q7T2H2 Q9I950 R4GIR0	FGF-18 FGF-3 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF8 FGFRL1	Gallus gallus (chicken)
Syndecan interactions	Fibroblast growth factor 2 Integrin beta Protein kinase C Syndecan-4 Syndecan Syndecan Transforming growth factor beta	F1NV24 H9CX01 P48800 P49416 Q8JIY0 Q92071 R4GHL2	FGF2 ITGB3 PRKCA SDC1 SDC2 SDC4 TGFB1	Gallus gallus (chicken)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor receptor 1 Fibroblast growth factor	P21804 R4GIR0	CEK1 FGF23 FGFR1	Gallus gallus (chicken)
GRB2:SOS provides linkage to MAPK signaling for Integrins	Fibronectin Focal adhesion kinase 1 Growth factor receptor-bound protein 2 Integrin beta Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1b SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5PEZ2 A3R0S3 F1NSA8 P00523 P11722 Q00944 Q5ZHX1 Q92071	FAK FAK1 FN1 GRB2 ITGB3 PTK2 RAP1A RAP1B SOS1 SRC	Gallus gallus (chicken)
Fibronectin matrix formation	Fibronectin	P11722	FN1	Gallus gallus (chicken)
NFkB and MAPK activation mediated by TRAF6	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 PPM-type phosphatase domain-containing protein Phase 2 flagellin Polyubiquitin-B TNF receptor-associated factor Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 5 Toll/interleukin-1 receptor domain-containing adapter protein Ubiquitin-ribosomal protein eL40 fusion protein (Fragment) Ubiquitin-ribosomal protein eS31 fusion protein	A0A8V0XHS1 A5H0S2 A5HNF6 E1C626 P06179 P0CG62 P52616 P62985 P79781 Q2XQ10 Q4U127 Q5F382 Q5GR02 Q5WA51 Q5ZJM6 Q5ZJW3 Q7ZTG5 Q9DD78	H2 LY96 MYD88 RCJMB04_15c17 RCJMB04_17b10 RCJMB04_29d24 RPS27A TIRAP TLR1 TLR15 TLR1Lb TLR2-1 TLR4 TLR5 TRAF6 UBA52 UBA80 UBB UBCEP2 flaF fliC fljB hag	Gallus gallus (chicken)
MyD88 cascade initiated on plasma membrane	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 Phase 2 flagellin Toll-like receptor 2 Toll-like receptor 5	A5HNF6 P06179 P52616 Q2XQ10 Q5F382 Q5GR02 Q5ZJM6	H2 MYD88 RCJMB04_17b10 RCJMB04_29d24 TLR15 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
TLR5 cascade	Flagellin Phase 2 flagellin Toll-like receptor 5	P06179 P52616 Q5GR02	H2 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin beta B chain TGF-beta family profile domain-containing protein Thyrotropin subunit beta	A0A3Q2TUG3 F1NJD3 O57340 Q8QGF8 R4GIS0	CGA FSH beta FSHB FSHb INHBB INHBE TSHB	Gallus gallus (chicken)
Hormone ligand-binding receptors	Follitropin subunit beta Glycoprotein hormones alpha chain Progonadoliberin-1 Thyrotropin subunit beta Type 1/III gonadotropin-releasing hormone receptor hexahelical variant	B5G4W1 F1NJD3 O57340 P37042 Q8QGF8	CGA FSH beta FSHB FSHb GNRH1 GNRHR1/III TSHB	Gallus gallus (chicken)

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