GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **263** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Glycolysis	ATP-dependent 6-phosphofructokinase Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucosamine-6-phosphate isomerase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglucomutase 2 like 1 Phosphoglycerate mutase 1 Phosphoglycerate mutase Pyruvate kinase PKM Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 E1C878 F1NAA5 F1NKB6 P00356 P00548 P00940 P07341 Q5ZHV4 Q5ZLA0 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 GAPD GAPDH GNPDA1 GNPDA2 GPI PFKL PGAM1 PGM2L1 PKM RCJMB04_32o10 TPI1	Gallus gallus (chicken)	G58161NS
Gluconeogenesis	Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate mutase 1 Solute carrier family 37 member 4 Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 F1NKP4 F1NTA5 F1NTH9 P00356 P00940 P07341 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 G6PC2 GAPD GAPDH GPI PCK1 PGAM1 SLC37A4 TPI1	Gallus gallus (chicken)	G58161NS
Hyaluronan uptake and degradation	Beta-hexosaminidase Calcineurin B homologous protein 1 Glucuronidase beta Lymphatic vessel endothelial hyaluronan receptor 1	A0A1L1RSD2 E1C9I1 F1NTQ2 Q5ZM44	CHP CHP1 GUSB HEXB LYVE1	Gallus gallus (chicken)	G35674CY
HS-GAG degradation	Alpha-L-iduronidase Glucuronidase beta Glypican-1 Syndecan-4 Syndecan Syndecan	A0A1L1RSD2 F1NV24 F1P150 P49416 Q5F366 Q8JIY0	GPC1 GUSB RCJMB04_31l23 SDC1 SDC2 SDC4	Gallus gallus (chicken)	G01550VL G09546QO
Synthesis of 15-eicosatetraenoic acid derivatives	Hydroperoxide isomerase ALOXE3 Prostaglandin G/H synthase 2	A0A1L1RTQ1 P27607	ALOX15B CEF-147 PTGS2	Gallus gallus (chicken)
Degradation of the extracellular matrix	72 kDa type IV collagenase ADAM metallopeptidase with thrombospondin type 1 motif 5 Basigin Cathepsin V Decorin Disintegrin and metalloproteinase domain-containing protein 10 Matrix metallopeptidase 10 interstitial collagenase	A0A1L1RX77 E1C9D9 E1C9E0 F1NYJ1 F1P3S7 P17790 Q5F3N4 Q90611	ADAMTS5 BSG CTSV DCN MMP1 MMP10 MMP2 RCJMB04_11h1	Gallus gallus (chicken)
CS/DS degradation	Alpha-L-iduronidase Beta-hexosaminidase Decorin	A0A1L1RX77 F1NTQ2 Q5F366	DCN HEXB RCJMB04_31l23	Gallus gallus (chicken)	G27025MB
PI3K Cascade	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1P5Y5 P18460 P18461 P19596 P21804 P48800 P48801 Q197G3 Q4R0X9 Q5F4A2 Q5KRA4 Q90687 Q9I950 R4GIR0 R4GMB5	CEK1 CEK2 CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 Fgf16 Fgf7 GRB2 PIK3CB PIK3R1 PIK3R2 PTPN11	Gallus gallus (chicken)
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q90687 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 FRS2 Fgf16 Fgf7 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q2TTH8 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 Q90687 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FRS2 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 2 Leucine-rich repeat transmembrane protein FLRT3	A0A3Q2TTH8 E1BZW7 E1C6W5 F1NUK7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FLRT2 FLRT3	Gallus gallus (chicken)
Phospholipase C-mediated cascade; FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7	Gallus gallus (chicken)
Phospholipase C-mediated cascade: FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1	Gallus gallus (chicken)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor-like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 P48800 P48801 Q4R0X9 Q7T2H2 Q9I950 R4GIR0	FGF-18 FGF-3 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF8 FGFRL1	Gallus gallus (chicken)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor	A0A3Q2TTH8 P18461 P19596 P48801 Q5KRA4	CEK3 FGF-3 FGF1 FGF10 FGF3 FGF7 FGFR2 Fgf7	Gallus gallus (chicken)
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Transforming growth factor beta receptor 3	A0A3Q2TTH8 P19596 P21804 P48800 P48801 Q90998	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF3 FGFR1 TGFBR3	Gallus gallus (chicken)
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin beta B chain TGF-beta family profile domain-containing protein Thyrotropin subunit beta	A0A3Q2TUG3 F1NJD3 O57340 Q8QGF8 R4GIS0	CGA FSH beta FSHB FSHb INHBB INHBE TSHB	Gallus gallus (chicken)
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Leucine rich repeat containing 8 VRAC subunit C Leucine rich repeat containing 8 VRAC subunit D Lysosomal amino acid transporter 1 homolog NIPA like domain containing 3 Non imprinted in Prader-Willi/Angelman syndrome 2	A0A3Q2TZ76 E1BQK4 E1BR96 E1BYZ5 E1BZK2 E1C957 F1NBX2 Q5ZJX0	ANKH LOC107056693 LRRC8A LRRC8C LRRC8D NIPA2 NIPAL3 PQLC2 SLC66A1	Gallus gallus (chicken)
Negative regulation of the PI3K/AKT network	Acyl-coenzyme A thioesterase THEM4 PH domain and leucine rich repeat protein phosphatase 1 RAC-alpha serine/threonine-protein kinase	A0A3Q2U4X3 F1NJB8 R4GH73	AKT1 PHLPP1 THEM4	Gallus gallus (chicken)
NTRK2 activates RAC1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase	A0A3Q2U639 P25429 Q6LC82 Q91987	BDNF FYN NTRK2 TRKB cRac1A	Gallus gallus (chicken)
Reelin signalling pathway	DAB1, reelin adaptor protein SH3 domain-containing protein Tyrosine-protein kinase Very low-density lipoprotein receptor	A0A3Q2U639 P98165 Q5ZMQ7 Q6XBN6	DAB1 Dab1 FYN RCJMB04_1g20 VLDLR VTGR	Gallus gallus (chicken)
Activated NTRK3 signals through PI3K	NT-3 growth factor receptor Neurotrophin-3 Proto-oncogene tyrosine-protein kinase Src	A0A3Q2U804 P00523 Q91044	NTF3 NTRK3 SRC TRKC	Gallus gallus (chicken)
Activated NTRK3 signals through PLCG1	NT-3 growth factor receptor Neurotrophin-3	A0A3Q2U804 Q91044	NTF3 NTRK3 TRKC	Gallus gallus (chicken)
NTF3 activates NTRK3 signaling	NT-3 growth factor receptor Neurotrophin-3	A0A3Q2U804 Q91044	NTF3 NTRK3 TRKC	Gallus gallus (chicken)
ESR-mediated signaling	peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q2U9P1 Q646T7	FKBP4 FKBP5 FKBP51	Gallus gallus (chicken)

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