GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Toll-like receptor 4	A0A8V0XHS1 B0BL87 Q7ZTG5	Cd14 LY96 TLR4	Gallus gallus (chicken)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Fibronectin Focal adhesion kinase 1 Integrin beta Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1b small monomeric GTPase	F1NSA8 P00523 P11722 Q00944 Q04929 Q5ZHX1 Q92071	CRK FAK FAK1 FN1 ITGB3 PTK2 RAP1A RAP1B SRC	Gallus gallus (chicken)
Assembly of active LPL and LIPC lipase complexes	Lipoprotein lipase Uncharacterized protein furin	A0A1L1RJC1 P11602 Q91000	FURIN LOC101747868 LPL	Gallus gallus (chicken)
Collagen biosynthesis and modifying enzymes	ADAM metallopeptidase with thrombospondin type 1 motif 3 Collagen alpha-1(XVII) chain Collagen alpha-2(VI) chain Collagen type I alpha 1 chain Collagen type I alpha 2 chain Collagen type III alpha 1 chain Collagen type IV alpha 1 chain Collagen type XII alpha 1 chain Prolyl 3-hydroxylase 2 Serpin H1	A0A1D5P8P3 A0A1D5PE57 A0A1D5PYU1 A0A1L1RPW4 A0A5H1ZRJ7 F1NVD1 P13731 P15988 Q6JHU7 Q90584	ADAMTS3 BP180 BPAG2 COL12A1 COL17A1 COL1A1 COL1A2 COL3A1 COL4A1 COL6A2 HSP47 LEPREL1 P3H2 SERPINH1	Gallus gallus (chicken)
EGFR interacts with phospholipase C-gamma	Amphiregulin Betacellulin Epigen Epiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase	A0A1D5PKH0 F1NJR9 Q5EG71 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG HBEGF HEGFL	Gallus gallus (chicken)
FGFR3b ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor	P18460 P19596 Q4R0X9 Q9I950	CEK2 FGF-18 FGF1 FGF18 FGF8 FGFR3	Gallus gallus (chicken)
N-glycan trimming and elongation in the cis-Golgi				Gallus gallus (chicken)	G58161NS
Cross-presentation of soluble exogenous antigens (endosomes)	Hepatic lectin	P02707		Gallus gallus (chicken)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Fibronectin Focal adhesion kinase 1 Integrin beta Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAS guanyl-releasing protein 1 Rap guanine nucleotide exchange factor 4 Ras-related protein Rap-1b SHC-transforming protein 1 Tyrosine-protein kinase SYK protein-tyrosine-phosphatase small monomeric GTPase	A0A1D5NYP8 A0A1D5PMC0 A0A1I7Q402 A0A3Q2U4X3 F1N9Y5 F1NSA8 P00523 P11722 Q00944 Q5F3U4 Q5F3V4 Q5ZHX1 Q92071	AKT1 FAK FAK1 FN1 ITGB3 PTK2 PTPN1 RAP1A RAP1B RAPGEF4 RCJMB04_6d2 RCJMB04_6p10 SHC1 SRC SYK	Gallus gallus (chicken)
Processing of DNA double-strand break ends	BRISC and BRCA1-A complex member 2 Checkpoint protein Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 Fanconi anemia group J protein homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4 RAD1 checkpoint DNA exonuclease Rad9 RecQ-mediated genome instability protein 2 Replication factor A protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication protein A 14 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2	A0A1D5P2D1 A0A1D5P3M9 A0A1D5PSK5 A0A1D5PTJ5 A0A1D5PY49 A0A1L1RNY8 A0A1L1RUB9 A0A3Q2UDI2 A2IAR9 E1C4C7 F1NDD7 F1NJI2 F1P3C0 F1P4N0 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P53033 P62801 P63283 Q3YK19 Q5ZJJ2 Q5ZJM9 Q5ZKG3 Q5ZLH1 Q5ZM20 Q5ZML0 Q5ZMU6 Q76F79 Q9PSW9	BABAM2 BRE BRIP1 CCNA1 CCNA2 CDK2 DNA2 DNA2L FANCJ H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L HUS1 LOC100859381 LOC426037 PIAS4 PPP4R2 RAD1 RAD9A RCJMB04_6d17 RFC2 RFC3 RFC4 RMI2 RPA1 RPA3 SUMO2 TOPBP1 UBC9 UBCE9 UBE2I rad9	Gallus gallus (chicken)
RHO GTPases activate PAKs	Cell division control protein 42 homolog LIM domain kinase 1 Myosin light chain 12B Myosin regulatory light chain 2, smooth muscle major isoform Myosin regulatory light chain 2, smooth muscle minor isoform Myosin-9 Protein phosphatase 1 regulatory subunit 12A Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Uncharacterized protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A1D5PM19 A0A1L1RUU9 E1BS97 E1C3P6 F1N8W8 P02612 P24032 P62207 Q5ZJB0 Q6LC82 Q8QFP8 Q90623 Q90694	CDC42 LIMK1 MBS MYH9 MYL12B MYPT1 PAK1 PAK2 PAK3 PPP1CB PPP1R12A RCJMB04_19i21 cRac1A	Gallus gallus (chicken)
TGF-beta receptor signaling activates SMADs	Integrin beta Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor 3 Transforming growth factor beta Transforming growth factor beta Zinc finger FYVE domain-containing protein furin peptidylprolyl isomerase	A0A1D5NUH3 E1C6T3 F1NNP2 H9CX01 P84023 Q06900 Q8UWF3 Q90998 Q90999 Q90ZG0 Q91000 Q92071	ChALK5 FKBP12 FURIN ITGB3 LOC769000 MADH2 MADH3 SMAD3 TGFB1 TGFB2 TGFBR1 TGFBR2 TGFBR3 ZFYVE9	Gallus gallus (chicken)
P2Y receptors	Lysophosphatidic acid receptor 4 P2Y purinoceptor 1 P2Y purinoceptor 3	E1BWJ9 P34996 Q98907	LPAR4 P2RY1 P2RY3	Gallus gallus (chicken)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PT95 A3R0S3 E1BZW7 E1C021 P08642 P18460 P19596 P48800 Q197G3 Q4R0X9 Q5F352 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 HRAS HRAS1 KRAS NRAS PTPN11 SOS1	Gallus gallus (chicken)
Chromatin modifying enzymes	Histone H3.2 Protein-arginine deiminase protein-arginine deiminase	E1C0W6 P84229 S6BNL5	H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII PADI1 PADI2 cPAD1 cPAD2	Gallus gallus (chicken)
VEGFA-VEGFR2 Pathway	Adapter molecule crk Brain-specific angiogenesis inhibitor 1-associated protein 2 Cell division control protein 42 homolog Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Engulfment and cell motility 2 Focal adhesion kinase 1 GDP/GTP exchange factor VAV3 GTP-binding protein Integrin beta MAPK activated protein kinase 2 MAPK activated protein kinase 3 Mitogen-activated protein kinase 12 Nck-associated protein 1 Neutrophil cytosolic factor 4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 SH2 domain containing adaptor protein B Tyrosine-protein kinase Uncharacterized protein Vascular endothelial growth factor receptor 2 Wiskott-Aldrich syndrome protein family member mitogen-activated protein kinase non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A1D5NVK9 A0A1D5P0L1 A0A1D5PIQ5 A0A3Q2U1E9 A0A3Q2U639 A0A3Q2UHS2 A0A3Q2UPF3 A0A3Q3ACS4 E1BS97 E1BW56 E1C122 E1C2C5 F1NCY7 F1NE09 F1NLU9 F1NW21 F1P4Q4 O93467 P00523 Q00944 Q04929 Q5F4A2 Q5ZKT0 Q5ZL97 Q6LC82 Q8UUX6 Q90694 Q92071 R4GGM0	BAIAP2 CDC42 CRK CYFIP1 CYFIP2 ELMO2 FAK FAK1 FYN ITGB3 KDR MAPK12 MAPK14 MAPKAPK2 MAPKAPK3 NCF4 NCK1 NCKAP1 PAK2 PIK3CB PIK3R1 PIK3R2 PTK2 RCJMB04_7b13 RCJMB04_9e23 RHOA SHB SRC VAV3 WASF3 cRac1A cRhoA rhoA	Gallus gallus (chicken)
Biosynthesis of DPAn-3 SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Biosynthesis of EPA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Platelet Adhesion to exposed collagen	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor	A0A3Q2TTH8 P18461 P19596 P48801 Q5KRA4	CEK3 FGF-3 FGF1 FGF10 FGF3 FGF7 FGFR2 Fgf7	Gallus gallus (chicken)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin Epigen Epiregulin GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PKH0 A0A1D5PT95 A3R0S3 F1NJR9 P08642 Q5EG71 Q5F352 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
FGFR3c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Polypeptide N-acetylgalactosaminyltransferase	E1BZW7 E1C241 P18460 P19596 P48800 Q197G3 Q4R0X9 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16 GALNT3	Gallus gallus (chicken)
Galactose catabolism	Phosphoglucomutase-1	F1NN63	PGM1	Gallus gallus (chicken)	G93924TT
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Catenin beta-1 Catenin delta 1 Caveolin GDP/GTP exchange factor VAV3 Junction plakoglobin RAC-alpha serine/threonine-protein kinase RPTOR independent companion of MTOR complex 2 Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase TOR Target of rapamycin complex 2 subunit MAPKAP1 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A1D5NYE8 A0A3Q2U1A5 A0A3Q2U4X3 A0M8T8 E1BS97 E1C1V3 E1C3P6 F1N8W8 F1NMJ6 F1NUX4 Q5F3U4 Q6LC82 Q8AYD0 Q8UUX6 Q9W6S3 R4GH73	AKT1 CAV1 CDH5 CTNNB1 CTNND1 JUP MAPKAP1 MTOR PAK1 PAK2 PAK3 RCJMB04_6p10 RICTOR SIN1 THEM4 VAV3 cRac1A	Gallus gallus (chicken)
RET signaling	Docking protein 1 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0E4BA89 A0A1D5NYP8 A0A1D5P405 A0A1D5PEZ2 A0A1D5PZ39 A0A3Q3ACS4 A3R0S3 E1C021 E1C2C5 F1NHX1 O13156 P00523 Q5F4A2 Q90687 R4GHL2	DOK1 FRS2 GDNFRA GFRA1 GRB10 GRB2 PDLIM7 PIK3CB PIK3CD PIK3R1 PIK3R2 PRKCA PTPN11 SHC1 SOS1 SRC	Gallus gallus (chicken)

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