GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	GTP-binding protein Par-6 family cell polarity regulator alpha Polyubiquitin-B Protein kinase C TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 E1BQN6 F1P0U8 H9CX01 O93467 P0CG62 P79781 Q06900 Q90999	ChALK5 PARD6A PRKCZ RHOA RPS27A TGFB1 TGFBR1 TGFBR2 UBA80 UBB cRhoA rhoA	Gallus gallus (chicken)
Reelin signalling pathway	DAB1, reelin adaptor protein SH3 domain-containing protein Tyrosine-protein kinase Very low-density lipoprotein receptor	A0A3Q2U639 P98165 Q5ZMQ7 Q6XBN6	DAB1 Dab1 FYN RCJMB04_1g20 VLDLR VTGR	Gallus gallus (chicken)
CS/DS degradation	Alpha-L-iduronidase Beta-hexosaminidase Decorin	A0A1L1RX77 F1NTQ2 Q5F366	DCN HEXB RCJMB04_31l23	Gallus gallus (chicken)	G27025MB
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco	Q5F422	DEK	Gallus gallus (chicken)
Effects of PIP2 hydrolysis	Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor Protein kinase C delta type Protein kinase C Transient receptor potential cation channel subfamily C member 7	A0A1D5PLX8 F1NDU2 F1NJH1 F1NYQ1 F1P1X4 F1P3G1	DGKB DGKK ITPR2 PRKCD PRKCH TRPC7	Gallus gallus (chicken)
Metabolism of folate and pterines	Dihydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Solute carrier family 25 member 32 methylenetetrahydrofolate reductase (NADPH)	A0A1D5PVR1 A0A1D5PZX4 A3RKL3 E1BXL1 F1NJ67	DHFR MTHFR PCFT SLC19A1 SLC25A32 SLC46A1	Gallus gallus (chicken)
RET signaling	Docking protein 1 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0E4BA89 A0A1D5NYP8 A0A1D5P405 A0A1D5PEZ2 A0A1D5PZ39 A0A3Q3ACS4 A3R0S3 E1C021 E1C2C5 F1NHX1 O13156 P00523 Q5F4A2 Q90687 R4GHL2	DOK1 FRS2 GDNFRA GFRA1 GRB10 GRB2 PDLIM7 PIK3CB PIK3CD PIK3R1 PIK3R2 PRKCA PTPN11 SHC1 SOS1 SRC	Gallus gallus (chicken)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Pro-glucagon	A0A1D5P7Z5 A0A1D5PJA5 E1C1U6 F1NLV4 F1P3R0 M9NJI3 P01295 P68259	DPP4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP	Gallus gallus (chicken)	G58161NS
Common Pathway of Fibrin Clot Formation	Coagulation factor X Coagulation factor XIII A chain Endothelial protein C receptor Serpin family D member 1 Serpin family E member 2	A0A1D5PLZ2 E1BWG1 E1BWU2 P25155 Q4ADW2	F10 F13A1 FX PROCR SERPIND1 SERPINE2	Gallus gallus (chicken)
Intrinsic Pathway of Fibrin Clot Formation	Coagulation factor X Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Prolylcarboxypeptidase Serpin family D member 1 Serpin family E member 2 Tsukushi	A0A1D5PLZ2 A0A1D5PVG8 A0A3Q3AXX7 E1BWU2 F1P1G3 P25155 Q65Z91	F10 FX GP1BB GP9 LRRC54 PRCP SERPIND1 SERPINE2 TSK TSKU	Gallus gallus (chicken)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor X	P25155	F10 FX	Gallus gallus (chicken)
GRB2:SOS provides linkage to MAPK signaling for Integrins	Fibronectin Focal adhesion kinase 1 Growth factor receptor-bound protein 2 Integrin beta Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1b SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5PEZ2 A3R0S3 F1NSA8 P00523 P11722 Q00944 Q5ZHX1 Q92071	FAK FAK1 FN1 GRB2 ITGB3 PTK2 RAP1A RAP1B SOS1 SRC	Gallus gallus (chicken)
Signaling by SCF-KIT	GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5P405 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BQF3 E1C2C5 E1C7Z1 F1NZY8 P00523 P08642 P09324 Q08156 Q09108 Q5F352 Q5ZJK3 Q6DV79 Q90687 R4GHL2	FER FYN GRAP2 GRB10 GRB2 HRAS HRAS1 KIT KITLG KRAS NRAS PIK3R1 PIK3R2 PRKCA PTPN11 RCJMB04_17i9 SCF SOS1 SRC STAT3 TEC YES YES1	Gallus gallus (chicken)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor-like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 P48800 P48801 Q4R0X9 Q7T2H2 Q9I950 R4GIR0	FGF-18 FGF-3 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF8 FGFRL1	Gallus gallus (chicken)
Syndecan interactions	Fibroblast growth factor 2 Integrin beta Protein kinase C Syndecan-4 Syndecan Syndecan Transforming growth factor beta	F1NV24 H9CX01 P48800 P49416 Q8JIY0 Q92071 R4GHL2	FGF2 ITGB3 PRKCA SDC1 SDC2 SDC4 TGFB1	Gallus gallus (chicken)
ESR-mediated signaling	peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q2U9P1 Q646T7	FKBP4 FKBP5 FKBP51	Gallus gallus (chicken)
Keratan sulfate degradation	Beta-hexosaminidase Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	A0A1D5NTY7 F1NI04 F1NTQ2 O42235 P51890 Q9W6H0	FMOD GNS HEXB KERA LDC LUM OGN	Gallus gallus (chicken)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Fibronectin matrix formation	Fibronectin	P11722	FN1	Gallus gallus (chicken)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase Protein-tyrosine sulfotransferase protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	A0A3Q2UD60 E1BRW8 F1NGS3 Q5ZMU7 R4GG02	FN3K FN3KRP ICMT TPST1 TPST2	Gallus gallus (chicken)
Assembly of active LPL and LIPC lipase complexes	Lipoprotein lipase Uncharacterized protein furin	A0A1L1RJC1 P11602 Q91000	FURIN LOC101747868 LPL	Gallus gallus (chicken)
Regulation of KIT signaling	Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Yes Tyrosine-protein kinase	A0A1D5PEZ2 A0A3Q2U639 A3R0S3 P00523 P09324 Q08156 Q09108 R4GHL2	FYN GRB2 KIT KITLG PRKCA SCF SOS1 SRC YES YES1	Gallus gallus (chicken)
Regulation of FZD by ubiquitination	Frizzled-4 Leucine rich repeat containing G protein-coupled receptor 4 Leucine rich repeat containing G protein-coupled receptor 5 Polyubiquitin-B Protein Wnt-3a R-spondin 1 R-spondin 2 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PB24 E1BVU3 E1C2F8 I0IVW2 P0CG62 P79781 Q2LMP1 Q9IA05	FZ4 FZD4 LGR4 LGR5 RPS27A RSPO1 RSPO2 UBA80 UBB WNT3A	Gallus gallus (chicken)
WNT5A-dependent internalization of FZD4	Frizzled-4 Protein Wnt	Q9IA05 Q9YGX6	FZ4 FZD4 WNT5A	Gallus gallus (chicken)
GABA receptor activation	GABA(C) receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit beta-4 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid type A receptor subunit gamma3	A0A1D5PXS3 F1ND90 F1NXA6 F6SVX7 P19019 P19150 P21548 P24045 Q90845	GABRA1 GABRA2 GABRA6 GABRB2 GABRB3 GABRB4 GABRG2 GABRG3 GABRR2	Gallus gallus (chicken)
HDACs deacetylate histones	GATA zinc finger domain containing 2A High mobility group 20B Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone deacetylase 1 Metastasis associated 1 family member 3 PHD finger protein 21A RB binding protein 4, chromatin remodeling factor Transducin beta like 1 X-linked receptor 1	A0A1D5NXL1 A0A1D5PFQ6 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1C0L3 F1NP02 F2Z4M0 P02263 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 Q9PSW9 R4GGQ7	GATAD2A H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L HMG20B LOC426037 MTA3 PHF21A RBBP4 TBL1XR1	Gallus gallus (chicken)

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