GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Nonhomologous End-Joining (NHEJ)	BRISC and BRCA1-A complex member 2 Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Non-homologous end-joining factor 1 Protein artemis Protein inhibitor of activated STAT 4 Tyrosyl-DNA phosphodiesterase 2 X-ray repair cross complementing 4	A0A1D5P2D1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDC0 F1NDD7 F1NVP8 F1NW29 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P62801 Q5QJC2 Q5ZML0 Q9PSW9	BABAM2 BRE DCLRE1C H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 NHEJ1 PIAS4 SNM1C TDP2 XRCC4	Gallus gallus (chicken)
Processing of DNA double-strand break ends	BRISC and BRCA1-A complex member 2 Checkpoint protein Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 Fanconi anemia group J protein homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4 RAD1 checkpoint DNA exonuclease Rad9 RecQ-mediated genome instability protein 2 Replication factor A protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication protein A 14 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2	A0A1D5P2D1 A0A1D5P3M9 A0A1D5PSK5 A0A1D5PTJ5 A0A1D5PY49 A0A1L1RNY8 A0A1L1RUB9 A0A3Q2UDI2 A2IAR9 E1C4C7 F1NDD7 F1NJI2 F1P3C0 F1P4N0 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P53033 P62801 P63283 Q3YK19 Q5ZJJ2 Q5ZJM9 Q5ZKG3 Q5ZLH1 Q5ZM20 Q5ZML0 Q5ZMU6 Q76F79 Q9PSW9	BABAM2 BRE BRIP1 CCNA1 CCNA2 CDK2 DNA2 DNA2L FANCJ H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L HUS1 LOC100859381 LOC426037 PIAS4 PPP4R2 RAD1 RAD9A RCJMB04_6d17 RFC2 RFC3 RFC4 RMI2 RPA1 RPA3 SUMO2 TOPBP1 UBC9 UBCE9 UBE2I rad9	Gallus gallus (chicken)
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase	A0A1D5PEI3 A0A1D5PSH8 A0A3S5ZPV4 F1NEL5 Q5F407 Q6ZXD0 R4GKF3	B4GALT2 B4GALT6 LOC427873 MGAT4A MGAT5 SIAT8C ST8SIA6	Gallus gallus (chicken)	G81533KY
Keratan sulfate biosynthesis	Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Fibromodulin Hexosyltransferase Keratocan Lumican Mimecan Sulfotransferase	A0A1D5NTY7 A0A1D5NVT2 A0A1D5PSH8 A0A3S5ZPV4 O42235 P51890 Q11200 Q5ZK57 Q9W6H0	B3GNT2 B4GALT2 B4GALT6 CHST2 FMOD KERA LDC LUM OGN SIAT4A ST3GAL1	Gallus gallus (chicken)
O-linked glycosylation of mucins	Beta-1,4-galactosyltransferase C1GALT1 specific chaperone 1 Glucosaminyl (N-acetyl) transferase 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase	A0A1D5PGR9 A0A1D5PJE0 A0A3S5ZPV4 E1BSH4 E1C241 E1C421 F1NIE6 F1NU59 Q5F3G7 Q5F4C7 Q5ZJL1 Q5ZK57	B3GNT2 B3GNT5 B3GNT9 B4GALT6 C1GALT1 C1GALT1C1 GALNT1 GALNT3 GALNT7 GCNT1 GCNT4 RCJMB04_1b1	Gallus gallus (chicken)
A tetrasaccharide linker sequence is required for GAG synthesis	Beta-1,4-galactosyltransferase Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican-1 Syndecan-4 Syndecan Syndecan Xylosyltransferase 2	A0A1D5P9Q8 A0A1L1RX77 F1NU53 F1NV24 F1P150 P49416 Q2HPN7 Q8JIY0	B3GAT2 B4GAL-T7 DCN GPC1 SDC1 SDC2 SDC4 XYLT2	Gallus gallus (chicken)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase	E1BZG7 E1C2U3 E1C4T5 Q8UWB9 Q8UWC1	B3GALT1 B3GALT5 CFTII FUT10 FUT7 FUT9 cFuc-TIX	Gallus gallus (chicken)	G90387AM
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Beta-2-microglobulin CD1.2 antigen CD300 molecule like family member g CD40 ligand CD48 CXADR Ig-like cell adhesion molecule Cell surface glycoprotein CD200 receptor 1-A Ig-like domain-containing protein Integrin subunit alpha 4 KRAB domain containing zinc finger protein MHC BF1 class I MHC class I alpha chain 2 Triggering receptor expressed on myeloid cells 2 Uncharacterized protein	A0A1D5PIR0 A0A1D5PKL9 A0A1D5PLP7 A0ZXL5 F1NBK7 F1NSL7 K4L906 P21611 Q2YHT7 Q52Z74 Q5ZKJ6 Q95601 Q9I8D8 R4GFS8	B-FIV B2M BF1 BF2 BFIV21 CD1.2 CD1A2 CD200R1A CD300LG CD40L CD40LG CD48 ITGA4 KRABZFP RCJMB04_10g5 TNFSF5 TREM2 TSTD1	Gallus gallus (chicken)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Axin-1 Caveolin Protein Wnt-3a Protein Wnt	A0A1D5P395 A0M8T8 Q2LMP1 Q564K5	AXIN1 CAV1 WNT3A Wnt8c	Gallus gallus (chicken)
TCF dependent signaling in response to WNT	Axin 2 Axin-1 Catenin beta-1 Polyubiquitin-B Protein Wnt-3a Protein Wnt Protein Wnt Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A1D5NYE8 A0A1D5P395 A0A1D5P546 A0A1D5PPH8 A0A3Q2TX44 A1DYI3 P0CG62 P79781 Q2LMP1 Q9YGX6	AXIN1 AXIN2 CTNNB1 RPS27A UBA80 UBB USP34 WNT3 WNT3A WNT5A Wnt3	Gallus gallus (chicken)
ROS and RNS production in phagocytes	ATPase H+ transporting V0 subunit b Cytochrome b-245 light chain H(+)-transporting two-sector ATPase Natural resistance-associated macrophage protein 1 Neutrophil cytosolic factor 4 Nitric oxide synthase Uncharacterized protein V-type proton ATPase proteolipid subunit V-type proton ATPase subunit G V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 2 V-type proton ATPase subunit VATE1 ATPase Vacuolar proton pump subunit B	A0A1D5NVK9 A0A1D5P5R9 A0A1D5P6L6 A0A1D5PCU0 A0A1D5PP57 A0A1D5PZB7 A0A1L1RUN2 F1NBW2 P51027 Q5F337 Q5ZHL0 Q5ZJ19 Q5ZJC4 Q5ZKJ9 Q5ZKT0	ATP6V0A1 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D2 ATP6V0E1 ATP6V1A ATP6V1B2 ATP6V1G3 NCF4 NOS2 NRAMP1 RCJMB04_10e23 RCJMB04_38b23 RCJMB04_9e23 SLC11A1	Gallus gallus (chicken)
Insulin receptor recycling	ATPase H+ transporting V0 subunit b Cathepsin D H(+)-transporting two-sector ATPase Insulin Tyrosine-protein kinase receptor V-type proton ATPase proteolipid subunit V-type proton ATPase subunit G V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 2 V-type proton ATPase subunit VATE1 ATPase Vacuolar proton pump subunit B protein-tyrosine-phosphatase	A0A1D5P5R9 A0A1D5P6L6 A0A1D5P6T3 A0A1D5PCU0 A0A1D5PP57 A0A1I7Q402 A0A1L1RUN2 F1NBW2 P67970 Q05744 Q5ZHL0 Q5ZJ19 Q5ZJC4 Q5ZKJ9	ATP6V0A1 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D2 ATP6V0E1 ATP6V1A ATP6V1B2 ATP6V1G3 CTSD INS INSR PTPN1 RCJMB04_10e23	Gallus gallus (chicken)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Protein ATP1B4 SKI like proto-onco Ski oncogene Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 E1BSJ7 F1P0N0 P0CG62 P79781 P84023 Q2HZ96 Q8UWF3	ATP1B4 LOC769000 MADH2 MADH3 RPS27A SKI SKIL SMAD3 UBA80 UBB	Gallus gallus (chicken)
Basigin interactions	Basigin Caveolin Integrin alpha-6 Monocarboxylate transporter 1 Sodium/potassium-transporting ATPase subunit beta-3 interstitial collagenase	A0M8T8 E1C9D9 P17790 P26007 P33879 Q5ZLZ6	ATP1B3 BSG CAV1 ITGA6 MMP1 RCJMB04_4e8	Gallus gallus (chicken)
Ion homeostasis	ATP-sensitive inward rectifier potassium channel 11 Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Plasma membrane calcium-transporting ATPase 1 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit beta-3 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Stromal interaction molecule 1 calcium/calmodulin-dependent protein kinase	A0A1D5NWP2 A0A1D5PZT6 A0A1L1RKB7 A0A3Q2U0I3 F1NBC9 F1NGS8 F1P023 F1P1X4 P33879 Q000J5 Q5ZM59 Q6DMS2 Q98SH2 R4GK80	ATP1B3 ATP2A2 ATP2B1 ATP2B2 CAMK2A COX16 ITPR2 KCNJ11 NCX1 PLN PMCA1 RCJMB04_3a16 SLC8A1 SLC8A2 STIM1 TRPC1	Gallus gallus (chicken)
Ion transport by P-type ATPases	Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban FXYD domain-containing ion transport regulator PDZ domain-containing protein 11 Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase 1 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta calcium/calmodulin-dependent protein kinase	A0A1D5P8E2 A0A1L1RKB7 A0A3Q2U0I3 A0A3Q2U2N5 E1BX05 F1NGS8 F1NUR8 F1NZB7 F1P2K5 P33879 Q07420 Q5ZIK2 Q5ZM59 Q98SH2 R4GK80	ATP10B ATP12A ATP1B3 ATP2A2 ATP2B1 ATP2B2 ATP4B ATP8A1 ATP8A2 ATP9A ATP9B CAMK2A PDZD11 PDZK11 PLN PMCA1 RCJMB04_3a16	Gallus gallus (chicken)
Glycosphingolipid catabolism	Acid ceramidase Beta-hexosaminidase Mannose-6-phosphate receptor, cation dependent Sulfatase N-terminal domain-containing protein exo-alpha-sialidase sphingomyelin phosphodiesterase	A0A1D5PL80 A0A1L1RMY8 A0A3Q2TVY6 E1BYN0 F1NTQ2 R4GH41	ASAH1 HEXB LOC418658 M6PR NEU2 SMPD2	Gallus gallus (chicken)	G09546QO G27025MB G58161NS
Axonal growth stimulation	GTP-binding protein Rho GDP-dissociation inhibitor 1 Tumor necrosis factor receptor superfamily member 16	F1P3P3 O93467 P18519	ARHGDIA NGFR RHOA TNFRSF16 cRhoA rhoA	Gallus gallus (chicken)
RHO GTPases activate PKNs	3-phosphoinositide-dependent protein kinase 1 GTP-binding protein GTP-binding protein Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoC protein kinase C protein kinase C	A0A3Q3B2F1 E1BYS6 O93467 O93468 Q5F3U4 Q6LC82 Q9PSX7	ARHC PKN2 PKN3 RCJMB04_6p10 RHOA RHOB RHOC cRac1A cRhoA cRhoB rhoA rhoB	Gallus gallus (chicken)
VxPx cargo-targeting to cilium	ADP-ribosylation factor Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 7 Exocyst complex component 8 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A0A1D5P0R2 A0A1D5PP34 F1NHD9 F1P2A7 F1P3Y2 Q5F470 Q5ZJN2 Q5ZKR9	ARF4 EXOC2 EXOC3 EXOC7 EXOC8 RAB11A RAB8A RHO	Gallus gallus (chicken)
EGFR interacts with phospholipase C-gamma	Amphiregulin Betacellulin Epigen Epiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase	A0A1D5PKH0 F1NJR9 Q5EG71 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG HBEGF HEGFL	Gallus gallus (chicken)
GAB1 signalosome	Amphiregulin Betacellulin Epigen Epiregulin Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase Tyrosine-protein phosphatase non-receptor type 11	A0A1D5PKH0 A0A3Q3ACS4 A3R0S3 F1NJR9 P00523 Q5EG71 Q645M5 Q64EU6 Q90687 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL PIK3R1 PTPN11 SRC	Gallus gallus (chicken)
GRB2 events in EGFR signaling	Amphiregulin Betacellulin Epigen Epiregulin GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5PEZ2 A0A1D5PKH0 A0A1D5PT95 A3R0S3 F1NJR9 P08642 Q5EG71 Q5F352 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL HRAS HRAS1 KRAS NRAS SOS1	Gallus gallus (chicken)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin Epigen Epiregulin GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PKH0 A0A1D5PT95 A3R0S3 F1NJR9 P08642 Q5EG71 Q5F352 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin Betacellulin Epigen Epiregulin Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Neuregulin 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 beta Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma Phosphatidylinositol-5-phosphate 4-kinase type 2 beta Phosphoinositide 3-kinase adapter protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor subunit A Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase T cell receptor associated transmembrane adaptor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A1D5PKH0 A0A1D5PV96 A0A1D5PVP0 A0A3Q2TTH8 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 E1C2C5 F1NCL8 F1ND21 F1NHX1 F1NJR9 F1NRE1 F1P1P4 F1P5Y5 P00523 P18460 P18461 P19596 P21804 P48800 P48801 Q08156 Q09108 Q197G3 Q4R0X9 Q5EG71 Q5F337 Q5F4A2 Q5KRA4 Q645M5 Q64EU6 Q6LC82 Q90687 Q90WK2 Q9DDT2 Q9I950 Q9W7C5 R4GIR0 R4GMA6 R4GMB5	AREG BCAP BTC CEK1 CEK2 CEK3 EGFR EPGN EREG FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF19 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FRS2 FYN Fgf16 Fgf7 GRB2 HBEGF HEGFL KIT KITLG NRG2 PDGF-A (L) PDGFA PIK3AP1 PIK3CB PIK3CD PIK3R1 PIK3R2 PIP4K2B PIP5K1B PIP5K1C PTPN11 RCJMB04_38b23 RHOG SCF SRC TRAT1 cRac1A	Gallus gallus (chicken)

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