GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **263** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Regulation of FZD by ubiquitination	Frizzled-4 Leucine rich repeat containing G protein-coupled receptor 4 Leucine rich repeat containing G protein-coupled receptor 5 Polyubiquitin-B Protein Wnt-3a R-spondin 1 R-spondin 2 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PB24 E1BVU3 E1C2F8 I0IVW2 P0CG62 P79781 Q2LMP1 Q9IA05	FZ4 FZD4 LGR4 LGR5 RPS27A RSPO1 RSPO2 UBA80 UBB WNT3A	Gallus gallus (chicken)
WNT5A-dependent internalization of FZD4	Frizzled-4 Protein Wnt	Q9IA05 Q9YGX6	FZ4 FZD4 WNT5A	Gallus gallus (chicken)
GABA receptor activation	GABA(C) receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit beta-4 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid type A receptor subunit gamma3	A0A1D5PXS3 F1ND90 F1NXA6 F6SVX7 P19019 P19150 P21548 P24045 Q90845	GABRA1 GABRA2 GABRA6 GABRB2 GABRB3 GABRB4 GABRG2 GABRG3 GABRR2	Gallus gallus (chicken)
HDACs deacetylate histones	GATA zinc finger domain containing 2A High mobility group 20B Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone deacetylase 1 Metastasis associated 1 family member 3 PHD finger protein 21A RB binding protein 4, chromatin remodeling factor Transducin beta like 1 X-linked receptor 1	A0A1D5NXL1 A0A1D5PFQ6 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1C0L3 F1NP02 F2Z4M0 P02263 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 Q9PSW9 R4GGQ7	GATAD2A H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L HMG20B LOC426037 MTA3 PHF21A RBBP4 TBL1XR1	Gallus gallus (chicken)
Signaling by SCF-KIT	GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5P405 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BQF3 E1C2C5 E1C7Z1 F1NZY8 P00523 P08642 P09324 Q08156 Q09108 Q5F352 Q5ZJK3 Q6DV79 Q90687 R4GHL2	FER FYN GRAP2 GRB10 GRB2 HRAS HRAS1 KIT KITLG KRAS NRAS PIK3R1 PIK3R2 PRKCA PTPN11 RCJMB04_17i9 SCF SOS1 SRC STAT3 TEC YES YES1	Gallus gallus (chicken)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	GTP-binding protein Par-6 family cell polarity regulator alpha Polyubiquitin-B Protein kinase C TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 E1BQN6 F1P0U8 H9CX01 O93467 P0CG62 P79781 Q06900 Q90999	ChALK5 PARD6A PRKCZ RHOA RPS27A TGFB1 TGFBR1 TGFBR2 UBA80 UBB cRhoA rhoA	Gallus gallus (chicken)
Axonal growth stimulation	GTP-binding protein Rho GDP-dissociation inhibitor 1 Tumor necrosis factor receptor superfamily member 16	F1P3P3 O93467 P18519	ARHGDIA NGFR RHOA TNFRSF16 cRhoA rhoA	Gallus gallus (chicken)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Pannexin	A0A1D5P0I0 P18861 Q8UVE3	GJA7 GJC1 GJD2 PANX PANX1	Gallus gallus (chicken)
Neurotransmitter receptors and postsynaptic signal transmission	Glycine receptor beta	F1P037	GLRB	Gallus gallus (chicken)
Platelet Adhesion to exposed collagen	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
Thyroxine biosynthesis	Glycoprotein hormones alpha chain Thyrotropin subunit beta	F1NJD3 O57340	CGA TSHB	Gallus gallus (chicken)
HS-GAG biosynthesis	Glypican-1 Heparan sulfate 2-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase 2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-4 Syndecan Syndecan [heparan sulfate]-glucosamine N-sulfotransferase	E1BYQ4 E1C4I5 F1NL56 F1NV24 F1NW51 F1P150 P49416 Q76KB1 Q76KB2 Q76LW2 Q8JIY0 R4GJI3	GPC1 HS2ST HS2ST1 HS3ST1 HS3ST3A1 HS3ST4 HS3ST5 HS6ST1 HS6ST2 NDST2 SDC1 SDC2 SDC4	Gallus gallus (chicken)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A1D5NYP8 A0A1D5P405 A0A1D5P6T3 A0A1D5PEZ2 A3R0S3 P67970	GRB10 GRB2 INS INSR SHC1 SOS1	Gallus gallus (chicken)
Regulation of KIT signaling	Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Yes Tyrosine-protein kinase	A0A1D5PEZ2 A0A3Q2U639 A3R0S3 P00523 P09324 Q08156 Q09108 R4GHL2	FYN GRB2 KIT KITLG PRKCA SCF SOS1 SRC YES YES1	Gallus gallus (chicken)
Digestion	Guanylate cyclase activator 2B Guanylate cyclase	E1BZE2 R4GIC2	GUCA2B GUCY2C	Gallus gallus (chicken)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Hematopoietic prostaglandin D synthase Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2	A0A1D5PM03 E2IPN6 O73888 P27607	CEF-147 GSTS HPGDS PGDS PTGDS2 PTGES PTGS1 PTGS2	Gallus gallus (chicken)
Dectin-2 family	Hepatic lectin	P02707		Gallus gallus (chicken)
Butyrophilin (BTN) family interactions	Hepatic lectin	P02707		Gallus gallus (chicken)
Asparagine N-linked glycosylation	Hepatic lectin	P02707		Gallus gallus (chicken)
Cross-presentation of soluble exogenous antigens (endosomes)	Hepatic lectin	P02707		Gallus gallus (chicken)
Glucose transport	Hexokinase-1 Hexokinase-2 Phosphotransferase (Fragment) Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3	P28568 P46896 Q8AYP7 Q8AYP8 Q8JHA6 Q90592	GLUT1 GLUT2 GLUT3 HK1 HK2 SLC2A1 SLC2A2 SLC2A3	Gallus gallus (chicken)	G58161NS
Assembly of the ORC complex at the origin of replication	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Importin subunit alpha Karyopherin subunit beta 1	A0A1D5P1W7 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 F7B5S0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KPNA6 KPNB1 LOC100859381 LOC426037	Gallus gallus (chicken)
RNA Polymerase I Promoter Opening	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)

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