GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 176 - 200 of 263 in total
Pathway Name Protein Name ▼ UniProt ID Gene Symbol Organism GlyTouCan ID
Downregulation of TGF-beta receptor signaling
  • BAMBI
  • ChALK5
  • LOC769000
  • MADH2
  • MADH3
  • PMEPA1
  • RPS27A
  • SMAD3
  • SMAD7
  • STRAP
  • STUB1
  • TGFB1
  • TGFBR1
  • TGFBR2
  • UBA80
  • UBB
Gallus gallus (chicken)
Activated NTRK2 signals through PLCG1
  • BDNF
  • NTRK2
  • TRKB
Gallus gallus (chicken)
NTRK2 activates RAC1
  • BDNF
  • FYN
  • NTRK2
  • TRKB
  • cRac1A
Gallus gallus (chicken)
Activated NTRK2 signals through FRS2 and FRS3
  • BDNF
  • FRS2
  • GRB2
  • NTRK2
  • SOS1
  • TRKB
Gallus gallus (chicken)
Formation of the beta-catenin:TCF transactivating complex
  • BCL9
  • CDC73
  • CTNNB1
  • H2A-IX
  • H2AF
  • H2AFX
  • H2AZ2
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • H3-I
  • H3-II
  • H3-III
  • H3-IV
  • H3-IX
  • H3-V
  • H3-VI
  • H3-VII
  • H3-VIII
  • H3-X
  • H4-I
  • H4-II
  • H4-III
  • H4-IV
  • H4-V
  • H4-VI
  • H4-VII
  • HDAC1
  • HDAC1A
  • HIST1H2B5L
  • LEF1
  • LOC100859381
  • LOC426037
  • PYGO1
  • RBBP5
  • RCJMB04_25e24
  • RUVBL1
  • TCF7
  • TLE1
  • TLE3
Gallus gallus (chicken)
Myogenesis
  • BNIP2
  • CDC42
  • CDH2
  • CTNNB1
  • MAPK12
  • MAPK14
  • MEF2D
  • MRF4
  • MYF5
  • MYF6
  • MYOD1
  • MYOG
Gallus gallus (chicken)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • BAFF
  • CD40L
  • CD40LG
  • TNFSF13B
  • TNFSF5
  • TRAF3
Gallus gallus (chicken)
TNFR2 non-canonical NF-kB pathway
  • BAFF
  • CD40L
  • CD40LG
  • TNFRSF1B
  • TNFSF13B
  • TNFSF5
  • TRAF3
Gallus gallus (chicken)
Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • AXIN1
  • CAV1
  • WNT3A
  • Wnt8c
Gallus gallus (chicken)
TCF dependent signaling in response to WNT
  • AXIN1
  • AXIN2
  • CTNNB1
  • RPS27A
  • UBA80
  • UBB
  • USP34
  • WNT3
  • WNT3A
  • WNT5A
  • Wnt3
Gallus gallus (chicken)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
  • AMFR
  • RPS27A
  • UBA80
  • UBB
  • VCP
  • vcp
Gallus gallus (chicken)
Transcriptional regulation by small RNAs
  • AGO1
  • H2A-IX
  • H2AF
  • H2AFX
  • H2AZ2
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • H3-I
  • H3-II
  • H3-III
  • H3-IV
  • H3-IX
  • H3-V
  • H3-VI
  • H3-VII
  • H3-VIII
  • H3-X
  • H4-I
  • H4-II
  • H4-III
  • H4-IV
  • H4-V
  • H4-VI
  • H4-VII
  • HIST1H2B5L
  • LOC100859381
  • LOC426037
  • NUP155
  • NUP37
  • NUP42
  • NUP43
  • NUP50
  • NUP54
  • NUP58
  • POLR2B
  • POLR2C
  • POLR2E
  • POLR2L
  • RAN
  • RPB6
Gallus gallus (chicken)
Synthesis, secretion, and deacylation of Ghrelin
  • GCG
  • GH
  • GHRL
  • IGF1
  • INS
  • SEC11A
  • SPC22
  • SPCS3
  • ghr
  • ghre
Gallus gallus (chicken)
Scavenging by Class A Receptors
  • APOA1
  • COLEC11
  • HSP90B1
Gallus gallus (chicken)
Heme signaling
  • APOA1
  • HBAA
  • HBB
  • HBE1
  • MAFK
  • PCFT
  • PGRMC2
  • SLC46A1
  • TLR4
  • XPO1
Gallus gallus (chicken)
Peptide ligand-binding receptors
  • AGTR1
  • APLN
  • APLNR
  • APLNR1
  • BDKRB1
  • BRS3.5
  • CCK1R
  • CCKAR
  • ECE-1
  • EDN2
  • EDNRA
  • F2RL1
  • F2RL2
  • GAL
  • GALR
  • GPER1
  • GPR37L1
  • GRP
  • MC1R
  • MC4R
  • MC5R
  • MLNR
  • Mc1r
  • NMB
  • NMBR
  • NMS
  • NMU
  • NMUR1
  • NMUR2
  • NPBWR1
  • NPSR1
  • NPW
  • NPY
  • NPY1R
  • NPY2R
  • NPY4R
  • NPY5R
  • NTSR1
  • OPRK1
  • OPRL1
  • OPRM1
  • PENK
  • PMCH
  • PNOC
  • PPY
  • PROK2
  • PYY
  • SS1R
  • SS2
  • SS2R
  • SS3R
  • SST
  • SSTR1
  • SSTR2
  • SSTR4
  • SSTR5
  • TRH
  • TRHR
  • UTS2
  • UTS2R
  • XK
Gallus gallus (chicken)
Antimicrobial peptides
  • ANG
  • CATH
  • CATHB1
  • CATHL1
  • CATHL2
  • CATHL3
  • CHGA
  • CL2
  • CMAP27
  • GNLY
  • LYZ
Gallus gallus (chicken)
Adherens junctions interactions
  • ANG
  • CDH12
  • CDH13
  • CDH18
  • CDH2
  • CDH5
  • CDH6
  • CDH7
  • CL2
  • CTNNB1
  • CTNND1
  • JUP
  • NECTIN3
Gallus gallus (chicken)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • AR
  • H2A-IX
  • H2AF
  • H2AFX
  • H2AZ2
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • H3-I
  • H3-II
  • H3-III
  • H3-IV
  • H3-IX
  • H3-V
  • H3-VI
  • H3-VII
  • H3-VIII
  • H3-X
  • H4-I
  • H4-II
  • H4-III
  • H4-IV
  • H4-V
  • H4-VI
  • H4-VII
  • HIST1H2B5L
  • LOC100859381
  • LOC426037
Gallus gallus (chicken)
Ub-specific processing proteases
  • ADRB2
  • AR
  • AXIN1
  • AXIN2
  • CCNA1
  • CCNA2
  • CDC20
  • ChALK5
  • DDB2
  • H2A-IX
  • H2AFX
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • HIST1H2B5L
  • LOC426037
  • LOC769000
  • MADH2
  • MADH3
  • MDM2
  • MYC
  • PTRH2
  • RPS27A
  • RUVBL1
  • SIAH2
  • SKP2
  • SMAD1
  • SMAD3
  • SMAD7
  • SNX3
  • TGFBR1
  • TOMM20
  • TOMM70
  • TRAF6
  • UAF1
  • UBA80
  • UBB
  • USP12
  • USP15
  • USP34
  • USP44
  • Ufd1l
  • WDR20
  • WDR48
Gallus gallus (chicken)
EGFR interacts with phospholipase C-gamma
  • AREG
  • BTC
  • EGFR
  • EPGN
  • EREG
  • HBEGF
  • HEGFL
Gallus gallus (chicken)
GAB1 signalosome
  • AREG
  • BTC
  • EGFR
  • EPGN
  • EREG
  • GRB2
  • HBEGF
  • HEGFL
  • PIK3R1
  • PTPN11
  • SRC
Gallus gallus (chicken)
GRB2 events in EGFR signaling
  • AREG
  • BTC
  • EGFR
  • EPGN
  • EREG
  • GRB2
  • HBEGF
  • HEGFL
  • HRAS
  • HRAS1
  • KRAS
  • NRAS
  • SOS1
Gallus gallus (chicken)
SHC1 events in EGFR signaling
  • AREG
  • BTC
  • EGFR
  • EPGN
  • EREG
  • GRB2
  • HBEGF
  • HEGFL
  • HRAS
  • HRAS1
  • KRAS
  • NRAS
  • SHC1
  • SOS1
Gallus gallus (chicken)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • AREG
  • BCAP
  • BTC
  • CEK1
  • CEK2
  • CEK3
  • EGFR
  • EPGN
  • EREG
  • FGF-18
  • FGF-3
  • FGF1
  • FGF10
  • FGF18
  • FGF19
  • FGF2
  • FGF23
  • FGF3
  • FGF4
  • FGF6
  • FGF7
  • FGF8
  • FGFR1
  • FGFR2
  • FGFR3
  • FGFR4
  • FRS2
  • FYN
  • Fgf16
  • Fgf7
  • GRB2
  • HBEGF
  • HEGFL
  • KIT
  • KITLG
  • NRG2
  • PDGF-A (L)
  • PDGFA
  • PIK3AP1
  • PIK3CB
  • PIK3CD
  • PIK3R1
  • PIK3R2
  • PIP4K2B
  • PIP5K1B
  • PIP5K1C
  • PTPN11
  • RCJMB04_38b23
  • RHOG
  • SCF
  • SRC
  • TRAT1
  • cRac1A
Gallus gallus (chicken)

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024