GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **263** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase Protein-tyrosine sulfotransferase protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	A0A3Q2UD60 E1BRW8 F1NGS3 Q5ZMU7 R4GG02	FN3K FN3KRP ICMT TPST1 TPST2	Gallus gallus (chicken)
Creation of classical C3 convertase	Complement 4 Complement C1q B chain Complement C1q subcomponent subunit A Complement C1s subcomponent Complement factor B-like protease (Fragment) Ig lambda chain C region Ig lambda chain V-1 region Ig mu chain C region MAp19 MHC-linked complement C4 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein VH1 protein (Fragment) complement subcomponent C1r	A0A3Q2UG72 A0A8V0Z078 A2N884 F1NAB7 F1NH19 P01875 P04210 P20763 P81475 Q076D6 Q5F3N3 Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	C1QA C1QB C1R C4 C4-2 MASP2 MBL RCJMB04_11h6 VH1	Gallus gallus (chicken)
Complement Cascade	Complement 4 Complement C3 Complement C5 Complement factor B-like protease (Fragment) Complement regulatory GPI-anchor protein Complement regulatory membrane protein MHC-linked complement C4	A0A3Q2UG72 A0A8V1AM71 P81475 Q076D6 Q4AEI5 Q90633 Q9DEG0	C4 C4-2 C5 CREG Cremp	Gallus gallus (chicken)
Lectin pathway of complement activation	Collectin-10 Collectin-11 Mannose-binding protein	A0A3Q3A736 Q2LK95 Q98TA4	CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell-activating factor BAFF CD40 ligand TNF receptor-associated factor	A0A3Q3AAA5 Q8JHJ4 Q9I8D8	BAFF CD40L CD40LG TNFSF13B TNFSF5 TRAF3	Gallus gallus (chicken)
GP1b-IX-V activation signalling	14-3-3 protein zeta Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Phosphatidylinositol 3-kinase regulatory subunit alpha Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Tsukushi	A0A3Q3ACS4 A0A3Q3AXX7 F1P1G3 P00523 P05625 Q5ZKC9 Q65Z91	GP1BB GP9 LRRC54 MIL PIK3R1 RAF1 SRC TSK TSKU YWHAZ	Gallus gallus (chicken)
PI-3K cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type 11	A0A3Q3ACS4 A3R0S3 E1BZW7 E1C021 P18460 P19596 P48800 Q197G3 Q4R0X9 Q90687 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 FRS2 Fgf16 GRB2 PIK3R1 PTPN11	Gallus gallus (chicken)
IRS-mediated signalling	Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q3ACS4 E1C2C5 Q5F4A2	PIK3CB PIK3R1 PIK3R2	Gallus gallus (chicken)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein Solute carrier family 5 member 7	A0A3Q3AVJ7 F1P4Q0	SLC44A5 SLC5A7	Gallus gallus (chicken)
Platelet Adhesion to exposed collagen	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
RHO GTPases activate PKNs	3-phosphoinositide-dependent protein kinase 1 GTP-binding protein GTP-binding protein Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoC protein kinase C protein kinase C	A0A3Q3B2F1 E1BYS6 O93467 O93468 Q5F3U4 Q6LC82 Q9PSX7	ARHC PKN2 PKN3 RCJMB04_6p10 RHOA RHOB RHOC cRac1A cRhoA cRhoB rhoA rhoB	Gallus gallus (chicken)
Other interleukin signaling	Caspase-3 Interferon lambda receptor 1 Interferon lambda-3 Interleukin 34 Myelomonocytic growth factor Synaptosomal-associated protein 25 Syndecan Taxilin alpha Tyrosine-protein kinase	A0A3Q3B2W9 B4ER10 F1NMJ9 F1NV24 K9JA28 O93417 P13854 P60878 R4GIU3	CASP3 IFNL IFNL3 IFNLR1 IL28 IL28B IL28RA IL34 JAK1 SDC1 SNAP SNAP25 TXLNA	Gallus gallus (chicken)
NFkB and MAPK activation mediated by TRAF6	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 PPM-type phosphatase domain-containing protein Phase 2 flagellin Polyubiquitin-B TNF receptor-associated factor Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 5 Toll/interleukin-1 receptor domain-containing adapter protein Ubiquitin-ribosomal protein eL40 fusion protein (Fragment) Ubiquitin-ribosomal protein eS31 fusion protein	A0A8V0XHS1 A5H0S2 A5HNF6 E1C626 P06179 P0CG62 P52616 P62985 P79781 Q2XQ10 Q4U127 Q5F382 Q5GR02 Q5WA51 Q5ZJM6 Q5ZJW3 Q7ZTG5 Q9DD78	H2 LY96 MYD88 RCJMB04_15c17 RCJMB04_17b10 RCJMB04_29d24 RPS27A TIRAP TLR1 TLR15 TLR1Lb TLR2-1 TLR4 TLR5 TRAF6 UBA52 UBA80 UBB UBCEP2 flaF fliC fljB hag	Gallus gallus (chicken)
MyD88:TIRAP-dependent cascade initiated on plasma membrane	Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Myeloid differentiation primary response protein MyD88 Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1 Toll-like receptor 4 Toll/interleukin-1 receptor domain-containing adapter protein	A0A8V0XHS1 A5H0S2 A5HNF6 Q4U127 Q5F382 Q5WA51 Q5ZJM6 Q7ZTG5 Q9DD78	LY96 MYD88 RCJMB04_17b10 RCJMB04_29d24 TIRAP TLR1 TLR1Lb TLR2-1 TLR4	Gallus gallus (chicken)
TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Toll-like receptor 4	A0A8V0XHS1 B0BL87 Q7ZTG5	Cd14 LY96 TLR4	Gallus gallus (chicken)
Basigin interactions	Basigin Caveolin Integrin alpha-6 Monocarboxylate transporter 1 Sodium/potassium-transporting ATPase subunit beta-3 interstitial collagenase	A0M8T8 E1C9D9 P17790 P26007 P33879 Q5ZLZ6	ATP1B3 BSG CAV1 ITGA6 MMP1 RCJMB04_4e8	Gallus gallus (chicken)
TLR2 subfamily cascade	Toll-like receptor 1-like protein b Toll-like receptor 1 Toll-like receptor 2 type-1	A5H0S2 Q5WA51 Q9DD78	TLR1 TLR1Lb TLR2-1	Gallus gallus (chicken)
MyD88 cascade initiated on plasma membrane	Flagellin Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 Phase 2 flagellin Toll-like receptor 2 Toll-like receptor 5	A5HNF6 P06179 P52616 Q2XQ10 Q5F382 Q5GR02 Q5ZJM6	H2 MYD88 RCJMB04_17b10 RCJMB04_29d24 TLR15 TLR5 flaF fliC fljB hag	Gallus gallus (chicken)
Hormone ligand-binding receptors	Follitropin subunit beta Glycoprotein hormones alpha chain Progonadoliberin-1 Thyrotropin subunit beta Type 1/III gonadotropin-releasing hormone receptor hexahelical variant	B5G4W1 F1NJD3 O57340 P37042 Q8QGF8	CGA FSH beta FSHB FSHb GNRH1 GNRHR1/III TSHB	Gallus gallus (chicken)
Inactivation, recovery and regulation of the phototransduction cascade	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha G protein-coupled receptor kinase G protein-coupled receptor kinase Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Rhodopsin Serine/threonine-protein phosphatase	E1BTX9 E1C4P5 F1P3Y2 P79880 P79881 Q5ZKL2 Q90980	GCAP1 GCAP2 GRK4 GRK7 GUCA1A GUCA1B PPEF1 RHO	Gallus gallus (chicken)
P2Y receptors	Lysophosphatidic acid receptor 4 P2Y purinoceptor 1 P2Y purinoceptor 3	E1BWJ9 P34996 Q98907	LPAR4 P2RY1 P2RY3	Gallus gallus (chicken)
HS-GAG biosynthesis	Glypican-1 Heparan sulfate 2-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase 2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-4 Syndecan Syndecan [heparan sulfate]-glucosamine N-sulfotransferase	E1BYQ4 E1C4I5 F1NL56 F1NV24 F1NW51 F1P150 P49416 Q76KB1 Q76KB2 Q76LW2 Q8JIY0 R4GJI3	GPC1 HS2ST HS2ST1 HS3ST1 HS3ST3A1 HS3ST4 HS3ST5 HS6ST1 HS6ST2 NDST2 SDC1 SDC2 SDC4	Gallus gallus (chicken)
Digestion	Guanylate cyclase activator 2B Guanylate cyclase	E1BZE2 R4GIC2	GUCA2B GUCY2C	Gallus gallus (chicken)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase	E1BZG7 E1C2U3 E1C4T5 Q8UWB9 Q8UWC1	B3GALT1 B3GALT5 CFTII FUT10 FUT7 FUT9 cFuc-TIX	Gallus gallus (chicken)	G90387AM

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