GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 201 - 225 of 263 in total
Pathway Name Protein Name UniProt ID Gene Symbol ▼ Organism GlyTouCan ID
EGFR downregulation
  • AREG
  • ARHGEF7
  • BTC
  • CDC42
  • EGFR
  • EPGN
  • EREG
  • GRB2
  • HBEGF
  • HEGFL
  • RCJMB04_1g20
  • RPS27A
  • SH3GL2
  • SH3GL3
  • SH3P4
  • SPRY1
  • UBA80
  • UBB
Gallus gallus (chicken)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • AR
  • H2A-IX
  • H2AF
  • H2AFX
  • H2AZ2
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • H3-I
  • H3-II
  • H3-III
  • H3-IV
  • H3-IX
  • H3-V
  • H3-VI
  • H3-VII
  • H3-VIII
  • H3-X
  • H4-I
  • H4-II
  • H4-III
  • H4-IV
  • H4-V
  • H4-VI
  • H4-VII
  • HIST1H2B5L
  • LOC100859381
  • LOC426037
Gallus gallus (chicken)
Heme signaling
  • APOA1
  • HBAA
  • HBB
  • HBE1
  • MAFK
  • PCFT
  • PGRMC2
  • SLC46A1
  • TLR4
  • XPO1
Gallus gallus (chicken)
Scavenging by Class A Receptors
  • APOA1
  • COLEC11
  • HSP90B1
Gallus gallus (chicken)
Deposition of new CENPA-containing nucleosomes at the centromere
  • APITD1
  • CENPH
  • CENPI
  • CENPL
  • CENPM
  • CENPN
  • CENPO
  • CENPS
  • CENPT
  • CENPW
  • H2A-IX
  • H2AF
  • H2AFX
  • H2AZ2
  • H2B-I
  • H2B-II
  • H2B-III
  • H2B-IV
  • H2B-V
  • H2B-VI
  • H2B-VII
  • H2B-VIII
  • H4-I
  • H4-II
  • H4-III
  • H4-IV
  • H4-V
  • H4-VI
  • H4-VII
  • HIST1H2B5L
  • LOC100859381
  • LOC426037
  • MIS18A
  • OIP5
  • RBBP4
  • RUVBL1
Gallus gallus (chicken)
VLDLR internalisation and degradation
  • AP2A2
  • AP2M1
  • CLTA
  • NR1H3
  • RCJMB04_3l2
  • RPS27A
  • UBA80
  • UBB
  • VLDLR
  • VTGR
Gallus gallus (chicken)
MHC class II antigen presentation
  • AP1G1
  • AP1M1
  • AP1S2
  • AP2A2
  • AP2M1
  • ARF1
  • BLB1
  • BLB2
  • CLTA
  • CTSD
  • CTSV
  • Ii
  • RCJMB04_1m17
  • SH3GL2
  • SH3P4
Gallus gallus (chicken)
Miscellaneous transport and binding events
  • ANKH
  • LOC107056693
  • LRRC8A
  • LRRC8C
  • LRRC8D
  • NIPA2
  • NIPAL3
  • PQLC2
  • SLC66A1
Gallus gallus (chicken)
Adherens junctions interactions
  • ANG
  • CDH12
  • CDH13
  • CDH18
  • CDH2
  • CDH5
  • CDH6
  • CDH7
  • CL2
  • CTNNB1
  • CTNND1
  • JUP
  • NECTIN3
Gallus gallus (chicken)
Antimicrobial peptides
  • ANG
  • CATH
  • CATHB1
  • CATHL1
  • CATHL2
  • CATHL3
  • CHGA
  • CL2
  • CMAP27
  • GNLY
  • LYZ
Gallus gallus (chicken)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
  • AMFR
  • RPS27A
  • UBA80
  • UBB
  • VCP
  • vcp
Gallus gallus (chicken)
Post-translational modification: synthesis of GPI-anchored proteins
  • ALPL
  • B-FIV
  • BF1
  • BF2
  • BFIV21
  • BST1
  • CNTN5
  • CPM
  • FAR2
  • LOC101747868
  • LY6CLEL
  • LYPD1
  • LYPD6B
  • NRN1
  • NRN1L
  • OPCML
  • PRN-P
  • PRNP
  • RECK
  • RTN4R
  • SPRN
  • TECTB
  • THY1
Gallus gallus (chicken)
Synthesis of 15-eicosatetraenoic acid derivatives
  • ALOX15B
  • CEF-147
  • PTGS2
Gallus gallus (chicken)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
  • ALG12
  • DPAGT1
Gallus gallus (chicken)
Glycolysis
  • ALDOB
  • ALDOC
  • ENO2
  • ENO4
  • GAPD
  • GAPDH
  • GNPDA1
  • GNPDA2
  • GPI
  • PFKL
  • PGAM1
  • PGM2L1
  • PKM
  • RCJMB04_32o10
  • TPI1
Gallus gallus (chicken)
Gluconeogenesis
  • ALDOB
  • ALDOC
  • ENO2
  • ENO4
  • G6PC2
  • GAPD
  • GAPDH
  • GPI
  • PCK1
  • PGAM1
  • SLC37A4
  • TPI1
Gallus gallus (chicken)
Post-translational protein phosphorylation
  • ALB
  • APLP2
  • APOA1
  • BMP4
  • CCN1
  • CDH2
  • CG-1B
  • CST3
  • CYR61
  • DNAJC3
  • FGF23
  • FN1
  • FUCA2
  • HSP90B1
  • IGFBP5
  • IL6
  • MATN3
  • MFGE8
  • MGAT4A
  • MXRA8
  • PENK
  • PNPLA2
  • PRSS23
  • QSCN6
  • QSOX
  • QSOX1
  • RCJMB04_11h1
  • RCN1
  • SDC2
  • SERPIND1
  • SOX
  • STC2
Gallus gallus (chicken)
Regulation of IGF Activity by IGFBP
  • ALB
  • APLP2
  • APOA1
  • BMP4
  • CCN1
  • CDH2
  • CG-1B
  • CST3
  • CYR61
  • DNAJC3
  • FGF23
  • FN1
  • FUCA2
  • HSP90B1
  • IGF1
  • IGF2
  • IGFBP2
  • IGFBP5
  • IL6
  • MATN3
  • MFGE8
  • MGAT4A
  • MXRA8
  • PENK
  • PNPLA2
  • PRSS23
  • QSCN6
  • QSOX
  • QSOX1
  • RCJMB04_11h1
  • RCN1
  • SDC2
  • SERPIND1
  • SOX
  • STC2
Gallus gallus (chicken)
Negative regulation of the PI3K/AKT network
  • AKT1
  • PHLPP1
  • THEM4
Gallus gallus (chicken)
Integrin signaling
  • AKT1
  • FAK
  • FAK1
  • FN1
  • ITGB3
  • PTK2
  • PTPN1
  • RAP1A
  • RAP1B
  • RAPGEF4
  • RCJMB04_6d2
  • RCJMB04_6p10
  • SHC1
  • SRC
  • SYK
Gallus gallus (chicken)
VEGFR2 mediated vascular permeability
  • AKT1
  • CAV1
  • CDH5
  • CTNNB1
  • CTNND1
  • JUP
  • MAPKAP1
  • MTOR
  • PAK1
  • PAK2
  • PAK3
  • RCJMB04_6p10
  • RICTOR
  • SIN1
  • THEM4
  • VAV3
  • cRac1A
Gallus gallus (chicken)
Extra-nuclear estrogen signaling
  • AKT1
  • AREG
  • BTC
  • CAV1
  • EGFR
  • EPGN
  • EREG
  • FAK
  • FAK1
  • GNAI1
  • GNAI2
  • GNAI3
  • GNAT3
  • GNB1
  • GNB3
  • GNB4
  • GNG10
  • GNG12
  • GNG13
  • GNG2
  • GNG5
  • GNGT2
  • Galphai3
  • HBEGF
  • HEGFL
  • MMP10
  • MMP2
  • PIK3R1
  • PIK3R2
  • PTK2
  • SHC1
  • SPHK1
  • SRC
  • ZDHHC21
  • ZDHHC7
Gallus gallus (chicken)
PI3K/AKT Signaling
  • AKT1
  • AREG
  • BCAP
  • BTC
  • CEK1
  • CEK2
  • CEK3
  • EGFR
  • EPGN
  • EREG
  • FGF-18
  • FGF-3
  • FGF1
  • FGF10
  • FGF18
  • FGF19
  • FGF2
  • FGF23
  • FGF3
  • FGF4
  • FGF6
  • FGF7
  • FGF8
  • FGFR1
  • FGFR2
  • FGFR3
  • FGFR4
  • FRS2
  • FYN
  • Fgf16
  • Fgf7
  • GRB2
  • HBEGF
  • HEGFL
  • KIT
  • KITLG
  • MAPKAP1
  • MTOR
  • NRG2
  • PDGF-A (L)
  • PDGFA
  • PIK3AP1
  • PIK3CB
  • PIK3CD
  • PIK3R1
  • PIK3R2
  • PTPN11
  • RCJMB04_38b23
  • RCJMB04_6p10
  • RHOG
  • RICTOR
  • SCF
  • SGK
  • SGK1
  • SIN1
  • SRC
  • THEM4
  • TRAT1
  • cRac1A
Gallus gallus (chicken)
Transcriptional and post-translational regulation of MITF-M expression and activity
  • AIMP1
  • DARS
  • EPRS
  • KIT
  • KITLG
  • RPS6KA
  • RSK
  • SCF
  • WNT3A
  • XPO1
  • chPKCI
Gallus gallus (chicken)
Peptide ligand-binding receptors
  • AGTR1
  • APLN
  • APLNR
  • APLNR1
  • BDKRB1
  • BRS3.5
  • CCK1R
  • CCKAR
  • ECE-1
  • EDN2
  • EDNRA
  • F2RL1
  • F2RL2
  • GAL
  • GALR
  • GPER1
  • GPR37L1
  • GRP
  • MC1R
  • MC4R
  • MC5R
  • MLNR
  • Mc1r
  • NMB
  • NMBR
  • NMS
  • NMU
  • NMUR1
  • NMUR2
  • NPBWR1
  • NPSR1
  • NPW
  • NPY
  • NPY1R
  • NPY2R
  • NPY4R
  • NPY5R
  • NTSR1
  • OPRK1
  • OPRL1
  • OPRM1
  • PENK
  • PMCH
  • PNOC
  • PPY
  • PROK2
  • PYY
  • SS1R
  • SS2
  • SS2R
  • SS3R
  • SST
  • SSTR1
  • SSTR2
  • SSTR4
  • SSTR5
  • TRH
  • TRHR
  • UTS2
  • UTS2R
  • XK
Gallus gallus (chicken)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024