GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Synthesis of 15-eicosatetraenoic acid derivatives	Hydroperoxide isomerase ALOXE3 Prostaglandin G/H synthase 2	A0A1L1RTQ1 P27607	ALOX15B CEF-147 PTGS2	Gallus gallus (chicken)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2b	O13076 P49892	ADORA1 ADORA2B	Gallus gallus (chicken)
Myogenesis	BCL2 interacting protein 2 Cadherin-2 Catenin beta-1 Cell division control protein 42 homolog Mitogen-activated protein kinase 12 Myocyte enhancer factor 2D Myogenic factor 6 Myogenic factor Myogenic factor Myogenin mitogen-activated protein kinase	A0A1D5NYE8 A0A1D5NYL4 A0A1D5PIQ5 F1NEC1 F1NHM3 F1NLU9 P10288 P17920 Q01795 Q90694 R4GMI9	BNIP2 CDC42 CDH2 CTNNB1 MAPK12 MAPK14 MEF2D MRF4 MYF5 MYF6 MYOD1 MYOG	Gallus gallus (chicken)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Tsukushi	A0A3Q3AXX7 F1P1G3 Q65Z91	GP1BB GP9 LRRC54 TSK TSKU	Gallus gallus (chicken)
Keratan sulfate degradation	Beta-hexosaminidase Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	A0A1D5NTY7 F1NI04 F1NTQ2 O42235 P51890 Q9W6H0	FMOD GNS HEXB KERA LDC LUM OGN	Gallus gallus (chicken)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
VLDLR internalisation and degradation	AP-2 complex subunit alpha AP-2 complex subunit mu Clathrin light chain Nuclear receptor subfamily 1 group H member 3 Polyubiquitin-B RING-type E3 ubiquitin transferase Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein Very low-density lipoprotein receptor	A0A1D5NV94 A0A1D5P546 A0A3Q2U5N2 A0A3Q2UH91 P0CG62 P79781 P98165 Q5F429 Q5ZMP6	AP2A2 AP2M1 CLTA NR1H3 RCJMB04_3l2 RPS27A UBA80 UBB VLDLR VTGR	Gallus gallus (chicken)
Clathrin-mediated endocytosis	AP-2 complex subunit alpha AP-2 complex subunit mu Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Amphiregulin ArfGAP with FG repeats 1 Betacellulin Bridging integrator 1 Clathrin light chain Clathrin light chain Endophilin-A1 Epigen Epiregulin Epsin 2 GTPase activating protein and VPS9 domains 1 Growth factor receptor-bound protein 2 Heat shock 70kDa protein 8 Interleukin-7 receptor subunit alpha Mannose-6-phosphate receptor, cation dependent NECAP endocytosis associated 2 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma Polyubiquitin-B Proheparin-binding EGF-like growth factor Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Ras-related protein Rab-5B Ras-related protein Rab-5C Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain-containing protein Scavenger receptor class B member 2 Solute carrier family 2 member 8 Sorting nexin Sorting nexin Synaptotagmin-1 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Wiskott-Aldrich syndrome like small monomeric GTPase	A0A1D5NV94 A0A1D5P546 A0A1D5P882 A0A1D5PFJ6 A0A1D5PKH0 A0A1D5PL88 A0A1L1RMY8 A0A3Q2TVQ8 A0A3Q2TZM7 A0A3Q2U5N2 A0A3Q2UI02 A1EA95 A3R0S3 E1BRR6 E1BTH9 E1BTY4 E1C007 E1C1G0 E1C4N7 E1C8Y3 F1NB17 F1ND21 F1NDA6 F1NJR9 F1NN78 F1NZ04 F1P4I3 P0CG62 P47191 P53488 P79781 Q5EG71 Q5ZHW4 Q5ZIP7 Q5ZJI7 Q5ZL74 Q5ZMP6 Q5ZMQ7 Q5ZMV5 Q645M5 Q64EU6 Q8AXV1 Q90WD0 Q98932 Q9W7C5	ACTR2 ACTR3 AGFG1 AP2A2 AP2M1 AREG ARP2 ARP3 ARPC1A ARPC3 ARPC5 BIN1 BTC CLTA CLTB EGFR EPGN EPN2 EREG GAPVD1 GRB2 HBEGF HEGFL HSPA8 IL7R M6PR NECAP2 PACSIN2 PACSIN3 PIK3C2A PIP5K1C RAB5A RAB5B RAB5C RCJMB04_1g20 RPS27A SCARB2 SH3GL2 SH3GL3 SH3P4 SLC2A8 SNX18 SNX9 SYBL1 SYT1 UBA80 UBB VAMP3 VAMP7 WASL	Gallus gallus (chicken)
Nonhomologous End-Joining (NHEJ)	BRISC and BRCA1-A complex member 2 Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Non-homologous end-joining factor 1 Protein artemis Protein inhibitor of activated STAT 4 Tyrosyl-DNA phosphodiesterase 2 X-ray repair cross complementing 4	A0A1D5P2D1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDC0 F1NDD7 F1NVP8 F1NW29 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P62801 Q5QJC2 Q5ZML0 Q9PSW9	BABAM2 BRE DCLRE1C H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 NHEJ1 PIAS4 SNM1C TDP2 XRCC4	Gallus gallus (chicken)
NTRK2 activates RAC1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase	A0A3Q2U639 P25429 Q6LC82 Q91987	BDNF FYN NTRK2 TRKB cRac1A	Gallus gallus (chicken)
Regulated proteolysis of p75NTR	Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin TNF receptor-associated factor Tumor necrosis factor alpha converting enzyme Tumor necrosis factor receptor superfamily member 16	E1C626 F1NGP7 P18519 Q04861 Q4JIM4 Q5QHR9	ADAM17 NFKB1 NGFR PSEN1 PSEN2 TNFRSF16 TRAF6	Gallus gallus (chicken)
TCF dependent signaling in response to WNT	Axin 2 Axin-1 Catenin beta-1 Polyubiquitin-B Protein Wnt-3a Protein Wnt Protein Wnt Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A1D5NYE8 A0A1D5P395 A0A1D5P546 A0A1D5PPH8 A0A3Q2TX44 A1DYI3 P0CG62 P79781 Q2LMP1 Q9YGX6	AXIN1 AXIN2 CTNNB1 RPS27A UBA80 UBB USP34 WNT3 WNT3A WNT5A Wnt3	Gallus gallus (chicken)
Lactose synthesis	Lysozyme C	P00698	LYZ	Gallus gallus (chicken)	G58161NS G74621DY
Signaling by EGFR	Amphiregulin Angio associated migratory cell protein Betacellulin Epigen Epiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase	A0A1D5PKH0 F1NJR9 P00523 Q5EG71 Q5ZLQ3 Q645M5 Q64EU6 Q9W7C5	AAMP AREG BTC EGFR EPGN EREG HBEGF HEGFL SRC	Gallus gallus (chicken)
Basigin interactions	Basigin Caveolin Integrin alpha-6 Monocarboxylate transporter 1 Sodium/potassium-transporting ATPase subunit beta-3 interstitial collagenase	A0M8T8 E1C9D9 P17790 P26007 P33879 Q5ZLZ6	ATP1B3 BSG CAV1 ITGA6 MMP1 RCJMB04_4e8	Gallus gallus (chicken)
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor	F1P0I0 P30372	CHRM2 CHRM5 CM2	Gallus gallus (chicken)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor X Osteocalcin	A0A1D5PRL0 P25155	BGLAP F10 FX	Gallus gallus (chicken)
HDACs deacetylate histones	GATA zinc finger domain containing 2A High mobility group 20B Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H4 Histone deacetylase 1 Metastasis associated 1 family member 3 PHD finger protein 21A RB binding protein 4, chromatin remodeling factor Transducin beta like 1 X-linked receptor 1	A0A1D5NXL1 A0A1D5PFQ6 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1C0L3 F1NP02 F2Z4M0 P02263 P0C1H3 P0C1H4 P0C1H5 P56517 P62801 P70082 P84229 Q9PSW9 R4GGQ7	GATAD2A H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-V H3-VI H3-VII H3-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L HMG20B LOC426037 MTA3 PHF21A RBBP4 TBL1XR1	Gallus gallus (chicken)
Creation of classical C3 convertase	Complement 4 Complement C1q B chain Complement C1q subcomponent subunit A Complement C1s subcomponent Complement factor B-like protease (Fragment) Ig lambda chain C region Ig lambda chain V-1 region Ig mu chain C region MAp19 MHC-linked complement C4 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein VH1 protein (Fragment) complement subcomponent C1r	A0A3Q2UG72 A0A8V0Z078 A2N884 F1NAB7 F1NH19 P01875 P04210 P20763 P81475 Q076D6 Q5F3N3 Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	C1QA C1QB C1R C4 C4-2 MASP2 MBL RCJMB04_11h6 VH1	Gallus gallus (chicken)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Ribokinase Transaldolase Transketolase	A0A1D5PC23 F1N8A7 F1P1A5 Q5ZIZ0 Q5ZJY1	RBKS RCJMB04_14h20 RCJMB04_22k15 TALDO1 TKTL1	Gallus gallus (chicken)	G31080DL
IRS-mediated signalling	Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q3ACS4 E1C2C5 Q5F4A2	PIK3CB PIK3R1 PIK3R2	Gallus gallus (chicken)
Stimuli-sensing channels	Acid-sensing ion channel 1 Anoctamin Bestrophin homolog Bestrophin homolog Chloride channel protein E3 ubiquitin-protein ligase Osteopetrosis associated transmembrane protein 1 Polyubiquitin-B RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase Sgk3 Serum/glucocorticoid regulated kinase 2 Sodium channel epithelial 1 subunit gamma Sodium leak channel, non-selective Stomatin like 3 Stomatin Two pore segment channel 1 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P0N6 A0A1D5P546 A0A1D5P6F6 E1BQ97 E1BSL8 E1BTV1 E1BZK5 E1C882 F1NGF2 F1NW62 F1P588 P05625 P0CG62 P79781 Q1XA76 Q5F372 Q5ZJQ4 Q5ZMW4 Q6U1I9	ACCN2 ANO10 ASIC1 BEST3 BEST4 CATSPER4 CLCN4 MIL NALCN OSTM1 RAF1 RCJMB04_16g8 RPS27A SCNN1G SGK SGK1 SGK2 STOM STOML3 UBA80 UBB WWP1	Gallus gallus (chicken)
NTF3 activates NTRK3 signaling	NT-3 growth factor receptor Neurotrophin-3	A0A3Q2U804 Q91044	NTF3 NTRK3 TRKC	Gallus gallus (chicken)
A tetrasaccharide linker sequence is required for GAG synthesis	Beta-1,4-galactosyltransferase Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican-1 Syndecan-4 Syndecan Syndecan Xylosyltransferase 2	A0A1D5P9Q8 A0A1L1RX77 F1NU53 F1NV24 F1P150 P49416 Q2HPN7 Q8JIY0	B3GAT2 B4GAL-T7 DCN GPC1 SDC1 SDC2 SDC4 XYLT2	Gallus gallus (chicken)
VxPx cargo-targeting to cilium	ADP-ribosylation factor Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 7 Exocyst complex component 8 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A0A1D5P0R2 A0A1D5PP34 F1NHD9 F1P2A7 F1P3Y2 Q5F470 Q5ZJN2 Q5ZKR9	ARF4 EXOC2 EXOC3 EXOC7 EXOC8 RAB11A RAB8A RHO	Gallus gallus (chicken)
Scavenging by Class A Receptors	Apolipoprotein A-I Collectin-11 Endoplasmin	A0A1D5PPN9 A0A3Q3A736 P08250	APOA1 COLEC11 HSP90B1	Gallus gallus (chicken)	G70323CJ G82576YO

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